Analysing the causes of deforestation in a CGE framework: The case of the Philippines

A computable general equilibrium (CGE) model is developed to evaluate some of the causes of deforestation in the Philippines. To quantify deforestation effects, the elasticities of various parameters of deforestation as identified in the literature are evaluated. The main conclusion derived is that the factors that have a relatively more direct influence on the level of harvest such as annual allowable cut would have a greater effect on deforestation rate than population growth and off-farm employment opportunities

Effects of global trade liberalisation on forestry products and forest sustainability using the GTAP model

The paper analyses the effects of trade liberalization amongst the leading exporters and importers of forest products, in particular, as well as global merchandise, in general. The study utilises the Global Trade Analysis Project (GTAP) model and its database, version 7. Given that forest products only comprise a small proportion of world merchandise trade, it is expected that trade liberalisation would cause small changes in terms of trade, real GDP, production, consumption and prices of forest products in most countries. In the short-run, national welfare in China and Japan would increase substantially by more than $US400 million while the opposite is true for the United States. In the long-run, national welfare in China, Mexico and Thailand would increase between$US230 million and $US295 million. Food production in Australia, Chile and New Zealand would increase slightly but significantly compared to other countries/regions. Similarly, food consumption in Malaysia and Thailand would increase by about 0.10 per cent

Deforestation in the Philippines: An economic assessment of government policy responses

In the case of a land constraint economy such as the Philippines, the efficient allocation of land to its various uses is essential. This constraint is further intensified by the growing population and increased demand for commercial land. The process of land classification is only the first step in managing land resources. A computable general equilibrium (CGE) model based on ORANI, a multi-sectoral model belonging to the Johansen class of CGE models was employed to ascertain the economy-wide effects of the reduction in forestry production due to conservation efforts. The paper also attempts to show the relative contribution of population growth and trade policies on deforestation in the case of the Philippines. The study evaluated some of the forestry policies recommended by the Philippine Master Plan for Forestry Development (1991-2015). In theory, the policies formulated would be viable and effective. The problem lies in the implementation especially of reforestation activities, which is the core of the Master Plan. The Philippine forests require intensive regeneration programs to revive the domestic logging industry and conservation programs to protect sensitive areas as well as the establishment of tree plantations. The study evaluated four policies from the Master Plan, namely the implementation of selective logging, imposition of stumpage tax on the forestry sector, lowering of forestry discount rates and the establishment of set-aside areas. The study found that moving into a selective logging regime and the establishment of set-aside areas would achieve forest conservation with little reduction in economic growth. Moreover, the results show that (domestic) population per se would not significantly increase deforestation. Whilst, export taxes are ineffective tools in reducing deforestation, trade liberalisation policies are beneficial to the economy as a whole

Assessment of heavy metal contamination in the sediments of Meda - Ela canal near Karadiyana semi-controlled dumpsite, Sri Lanka

The pollution of natural waterbodies with landfill leachate from dumpsites is a severe environmental issue all over the world. Karadiyana semi-controlled dumpsite in the Western province of Sri Lanka is one of the largest dumpsites in the country. The leachate generated in the dumpsite directly flows into Meda Ela canal which is a tributary of Bolgoda Lake Weras Ganga system causing a significant pollution threat on aquatic life. The current study assesses the contamination level of selected heavy metals in the sediments of Meda-Ela close to the dumpsite. The study was carried out for a period of one year from January - December 2018. The sediment samples were characterized with an alkaline pH ranging from 8.40 to 8.70. The electrical conductivity of the sediment was recorded with a mean value of 139.93 ± 26.7 µS/cm. The mean concentration of Cu in sediment was of 73.53± 2.52 mg/Kg and it falls into the EPA guideline for heavily polluted sediments. Total Cu concentration exceeds the threshold effect concentration but falls below the probable effect concentration. The total Fe concentration was relatively high (110.83 ±1.96 mg/Kg) among the measured metal species. The other metals, Cd, Cr and Zn was recorded with mean concentrations of 0.38 ± 0.03,103 ± 41.62, 94.4 ± 2.08 mg/Kg respectively. Pollution Load Index of the sediment was 0.87 and therefore it comes under no pollution category. This suggests that there is no appreciable input from anthropogenic sources. Based on geo- accumulation index, sediments are moderately polluted with respect to Cu and Cd.KEYWORDS:     Karadiyana, Sediments, Heavy metal, Geo-accumulation index, Pollution Loading Inde

Integrated approach for coastal hazards and risks in Sri Lanka

The devastating impact of the tsunami of 26 December 2004 on the shores of the Indian Ocean recalled the importance of knowledge and the taking into account of coastal hazards. Sri Lanka was one of the countries most affected by this tsunami (e.g. 30 000 dead, 1 million people homeless and 70% of the fishing fleet destroyed). Following this tsunami, as part of the French post-tsunami aid, a project to establish a Geographical Information System (GIS) on coastal hazards and risks was funded. This project aims to define, at a pilot site, a methodology for multiple coastal hazards assessment that might be useful for the post-tsunami reconstruction and for development planning. This methodology could be applied to the whole coastline of Sri Lanka. <br><br> The multi-hazard approach deals with very different coastal processes in terms of dynamics as well as in terms of return period. The first elements of this study are presented here. We used a set of tools integrating a GIS, numerical simulations and risk scenario modelling. While this action occurred in response to the crisis caused by the tsunami, it was decided to integrate other coastal hazards into the study. Although less dramatic than the tsunami these remain responsible for loss of life and damage. Furthermore, the establishment of such a system could not ignore the longer-term effects of climate change on coastal hazards in Sri Lanka. <br><br> This GIS integrates the physical and demographic data available in Sri Lanka that is useful for assessing the coastal hazards and risks. In addition, these data have been used in numerical modelling of the waves generated during periods of monsoon as well as for the December 2004 tsunami. Risk scenarios have also been assessed for test areas and validated by field data acquired during the project. The results obtained from the models can be further integrated into the GIS and contribute to its enrichment and to help in better assessment and mitigation of these risks. <br><br> The coastal-hazards-and-risks GIS coupled with modelling thus appears to be a very useful tool that can constitute the skeleton of a coastal zone management system. Decision makers will be able to make informed choices with regards to hazards during reconstruction and urban planning projects

Short term effects on liver and renal functions following chemotherapy treatment for breast cancer patients in oncology clinic, university hospital Kotelawala Defence University in Sri Lanka

Background: Breast cancer tops the global cancer incidence rates, having the highest rate of death among women. The primary objective of this study was to assess the impact of standard chemotherapy treatment dose adjusted for the Sri Lankan population, on hepatic and kidney function of breast cancer patients. Methods: The study conducted a cross-sectional, retrospective and prospective analysis of 75 breast cancer patients who received doxorubicin, cyclophosphamide, and paclitaxel chemotherapy regimen with normal liver and renal function at baseline at UHKDU oncology clinic. The study population had a mean age and BMI of 54.04±11.33 years and 26.7±3.89, respectively. Prior to starting the 16-cycle chemotherapy treatment, mean serum SGOT, SGPT, Creatinine, and eGFR values were 27.57 U/l, 31.32 U/l, 0.71 mg/dl, and 99.07 ml/minute/1.73 m2 respectively. Results: During the treatment, there was a statistically significant increase in the mean values of SGOT and SGPT (p<0.05), whereas there was no significant variation in the mean values of creatinine and eGFR (p>0.05) compared to the baseline results. The study identified a significant positive correlation in SGOT (r=0.793) and SGPT (r=0.872) values, while there was a noteworthy negative correlation (r=-0.757) between eGFR and chemotherapy cycle. Furthermore, there was a positive significant correlation between serum creatinine levels and chemotherapy cycle (r=0.579). Conclusions: The dosed adjusted chemotherapy regimen had a significant impact on hepatic function but had no statistically significant impact on renal function among the study population. Further research is recommended to evaluate the long-term effects of standard chemotherapy treatment on liver and kidney functions

Pancreatectomy for metastasis to the pancreas from colorectal cancer and reconstruction of superior mesenteric vein: a case report

<p>Abstract</p> <p>Introduction</p> <p>Tumors of the pancreatic head can infiltrate the superior mesenteric vein. In such cases, the deep veins of the lower limbs can serve as suitable autologous conduits for superior mesenteric vein reconstruction after its resection. Few data exist, however, describing the technique and the immediate patency of such reconstruction.</p> <p>Case report</p> <p>We present the case of a 70-year-old Caucasian man with a metachronous metastasis of colon cancer and infiltration of the uncinate pancreatic process, on the anterior surface of which the tumor was located. <it>En bloc </it>resection of the tumor was performed with resection of the superior mesenteric vein and reconstruction. A 10 cm segment of the superficial femoral vein was harvested for the reconstruction. The superficial femoral vein segment was inter-positioned in an end-to-end fashion. The post-operative conduit patency was documented ultrasonographically immediately post-operatively and after a six-month period. The vein donor limb presented subtle signs of post-operative venous hypertension with edema, which was managed with compression stockings and led to significant improvement after six months.</p> <p>Conclusion</p> <p>In cases of exploratory laparotomies with high clinical suspicion of pancreatic involvement, the potential need for vascular reconstruction dictates the preparation for leg vein harvest in advance. The superficial femoral vein provides a suitable conduit for the reconstruction of the superior mesenteric vein. This report supports the uncomplicated nature of this technique, since few data exist about this type of reconstruction.</p

CONSTANS imparts DNA sequence specificity to the histone fold NF-YB/NF-YC dimer

Nuclear Factor Y (NF-Y) is a heterotrimeric transcription factor that binds CCAAT elements. The NF-Y trimer is composed of a Histone Fold Domain (HFD) dimer (NF-YB/NF-YC) and NF-YA, which confers DNA sequence specificity. NF-YA shares a conserved domain with the CONSTANS, CONSTANS-LIKE, TOC1 (CCT) proteins. We show that CONSTANS (CO/B-BOX PROTEIN1 BBX1), a master flowering regulator, forms a trimer with Arabidopsis thaliana NF-YB2/NF-YC3 to efficiently bind the CORE element of the FLOWERING LOCUS T promoter. We term this complex NF-CO. Using saturation mutagenesis, electrophoretic mobility shift assays, and RNA-sequencing profiling of co, nf-yb, and nf-yc mutants, we identify CCACA elements as the core NF-CO binding site. CO physically interacts with the same HFD surface required for NF-YA association, as determined by mutations in NF-YB2 and NF-YC9, and tested in vitro and in vivo. The co-7 mutation in the CCT domain, corresponding to an NF-YA arginine directly involved in CCAAT recognition, abolishes NF-CO binding to DNA. In summary, a unifying molecular mechanism of CO function relates it to the NF-YA paradigm, as part of a trimeric complex imparting sequence specificity to HFD/DNA interactions. It is likely that members of the large CCT family participate in similar complexes with At-NF-YB and At-NF-YC, broadening HFD combinatorial possibilities in terms of trimerization, DNA binding specificities, and transcriptional regulation

CONSTANS imparts DNA sequence specificity to the histone fold NF-YB/NF-YC dimer

Nuclear Factor Y (NF-Y) is a heterotrimeric transcription factor that binds CCAAT elements. The NF-Y trimer is composed of a Histone Fold Domain (HFD) dimer (NF-YB/NF-YC) and NF-YA, which confers DNA sequence specificity. NF-YA shares a conserved domain with the CONSTANS, CONSTANS-LIKE, TOC1 (CCT) proteins. We show that CONSTANS (CO/B-BOX PROTEIN1 BBX1), a master flowering regulator, forms a trimer with Arabidopsis thaliana NF-YB2/NF-YC3 to efficiently bind the CORE element of the FLOWERING LOCUS T promoter. We term this complex NF-CO. Using saturation mutagenesis, electrophoretic mobility shift assays, and RNA-sequencing profiling of co, nf-yb, and nf-yc mutants, we identify CCACA elements as the core NF-CO binding site. CO physically interacts with the same HFD surface required for NF-YA association, as determined by mutations in NF-YB2 and NF-YC9, and tested in vitro and in vivo. The co-7 mutation in the CCT domain, corresponding to an NF-YA arginine directly involved in CCAAT recognition, abolishes NF-CO binding to DNA. In summary, a unifying molecular mechanism of CO function relates it to the NF-YA paradigm, as part of a trimeric complex imparting sequence specificity to HFD/DNA interactions. It is likely that members of the large CCT family participate in similar complexes with At-NF-YB and At-NF-YC, broadening HFD combinatorial possibilities in terms of trimerization, DNA binding specificities, and transcriptional regulation

Literature review and a preliminary study on leishmaniasis to inform community awareness campaigns in Sri Lanka

Background: Accurate knowledge about transmission and potential risk factors of leishmaniasis among residents in endemic areas is imperative. This paper presents a review of the existing literature on leishmaniasis risk factors in Sri Lanka and a preliminary study of the disease related awareness, attitudes and practices in an endemic area.Methods: Publications on epidemiology of leishmaniasis in Sri Lanka were reviewed. Data were collected using an interviewer administered questionnaire from 120 inhabitants in Dickwella Divisional Secretariat in the District of Matara by a multistage cluster sampling method.Results: Around 20 publications were reviewed, and potential risk factors identified. In the field survey, 21.7% (n=26/120) were aware of the name “leishmaniasis”. Disease vector was identified by 68.1% (n=64/94) through the shown picture and description. Acne form was known as a type of early leishmanial skin lesion by 81.1% (n=73/90). Potential risk factors such as cracks of house walls (55.8%, n=67/120), damp areas in houses (60.0%, n=72/120), animal burrows (45%, n=54/120) and livestock pens (12.5%, n=15/120) were abundant in this area. Western medical treatment was preferred by 78.9% (n=71/90) as the treatment option. Around 58.9% (n=53/90) of respondents felt that disease prevention is a combined responsibility of community and the government.Conclusions: Even though, potential environmental risk factors were abundant, this study found poor awareness regarding the salient aspects of leishmaniasis among the participants. They possessed positive attitudes towards curability of the disease, obtaining proper treatment and disease control.</p