Study of Effect of Nano-Silica on Strength and Durability Characteristics of High Volume Fly Ash Concrete for Pavement Construction

Increasing demands of cement concrete for construction of rigid pavements motivates for the utilization of other sustainable waste cementitious materials. High volume fly-ash concrete (HVFAC) which is composed of more than 50% fly-ash fulfils the aspiration of large volume of fly-ash which are produced world over. The disadvantage which the HVFAC has is its delayed gain of strength. Contemporary literature identifies nano-silica as the material which when added in small percentages in HVFAC has the potential to improve its strength and durability characteristics at an early age. The objective of the study is to investigate the strength and durability characteristics of HVFAC modified with addition of different percentages of nano-silica so that it can be used for construction of rigid pavements. The methodology of the study involves mix proportioning of HVFAC and introducing nano-silica powder in aqueous medium after mixing it thoroughly at 2500 rpm. Various tests related to strength and durability was carried out after 28, 56 and 90 days age of concrete. The tests related to strength namely flexural strength, compressive strength and split tensile strength tests were carried out. Durability characteristics were evaluated by permeability, sorptivity and rapid chloride penetration tests and were confirmed by density and ultrasonic pulse velocity test.  The test results show that the utilization of 2% nano-silica in HVFAC enhances the strength and durability characteristics to a level that are comparable to that of normal concrete after 28 days and thus, can be sustainably utilized for rigid pavement construction

Behrens-Fisher problem under the assumption of homogeneous coefficients of variation

Derivation of the likelihood ratio test of equality of two normal population means under the assumption of homogeneous coefficients of variation -- Derivation of the likelihood ratio statistic -- Power studies of the various test and conclusions

Pharmacotherapeutic Options for Visceral Leishmaniasis—Current Scenario

Visceral leishmaniasis (VL) or Kala-azar is a protozoal disease, which was previously regarded as one of the most neglected tropical diseases. Management of this disease is quite difficult, because it is said to affect the poorest of the poor. Previously Sodium Stibogluconate (SSG) was regarded as the gold standard treatment for VL. But due to the increasing unresponsiveness, to this drug various other drugs were tried and are still being tried. Pentamidine is very toxic and has been discarded of late. Amphotericin B and its lipid formulations are very effective but require hospital admission and monitoring. Oral drugs like Miltefosine have already been launched. An amino glycoside Paromomycin and another oral drug Sitamaquine are in the pipe line. Interferon gamma has been used with discouraging results

Tuberous sclerosis with visceral leishmaniasis: a case report

<p>Abstract</p> <p>Introduction</p> <p>Visceral leishmaniasis, a tropical infectious disease, is a major public health problem in India. Tuberous sclerosis, a congenital neuro-ectodermosis, is an uncommon disease which requires life long treatment.</p> <p>Case presentation</p> <p>A 15-year-old Indian patient, presented to the outpatient department of our institute with a high-grade fever for two months, splenomegaly and a history of generalized tonic-clonic convulsions since childhood. The clinical and laboratory findings suggested visceral leishmaniasis with tuberous sclerosis. The patient was treated with miltefosine and antiepileptics.</p> <p>Conclusion</p> <p>The patient responded well and in a follow up six months after presentation, she was found free of visceral leishmaniasis and seizures. Diagnosis and treatment of this rare combination of diseases is difficult.</p

Multivariate power series distributions and Neyman's properties for multinomials

A probelm of J. Neyman (in Classical and Contagious Discrete Distributions (G. P. Patil, Ed.), 1965, pp. 4-14) regarding a characterization of positive and negative multinomial distributions is studied in this paper. Some properties of multivariate power series distributions in general which should be of independent interest are also derived

Multivariate power series distributions and Neyman's properties for multinomials

A probelm of J. Neyman (in Classical and Contagious Discrete Distributions (G. P. Patil, Ed.), 1965, pp. 4-14) regarding a characterization of positive and negative multinomial distributions is studied in this paper. Some properties of multivariate power series distributions in general which should be of independent interest are also derived.positive multinomial distributions negative multinomial distributions power series distributions dispersion matrix linear regression

On the robustness of least squares procedures in regression models

The criterion robustness of the standard likelihood ratio test (LRT) under the multivariate normal regression model and also the inference robustness of the same test under the univariate set up are established for certain nonnormal distributions of errors. Restricting attention to the normal distribution of errors in the context of univariate regression models, conditions on the design matrix are established under which the usual LRT of a linear hypothesis (under homoscedasticity of errors) remains valid if the errors have an intraclass covariance structure. The conditions hold in the case of some standard designs. The relevance of C. R. Rao's (1967 In Proceedings Fifth Berkeley Symposium on Math. Stat. and Prob., Vol. 1, pp. 355-372) and G. Zyskind's (1967, Ann. Math. Statist.38 1092-1110) conditions in this context is discussed.Univariate and multivariate regression models least squares procedures maximum likelihood estimates likelihood ratio tests intraclass correlation matrix balanced block designs