Cutaneous manifestations Of COVID-19

The coronavirus 2019(COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), has had enormous health, economic, and social consequences. Cutaneous manifestations associated with COVID-19 probably reflect the activation of pathogenic pathways by the virus or a response to inflammatory processes, vascular or systemic complications, or even treatments. There is no previous detailed classification or description of the cutaneous manifestations of COVID‐19. This information may prove useful to manage patients and to recognize paucisymptomatic patients and might provide prognostic information. The recognition of paucisymptomatic patients could also be helpful for epidemiological control, especially in areas where diagnostic tests are scarce. This is a cross-sectional study among the COVID positive patients admitted in Index Medical College Hospital and Research Centre (Tertiary Care Centre) Indore from 1st May 2020 – 30th November 2020. Considered initially as of little relevance, the dermatological manifestations observed in patients with COVID-19 are both heterogeneous and complex. 5 main categories of lesions identified; vesicular rashes, urticarial rashes, acral lesions, maculopapular rashes and livedoid & necrotic lesions

Metabolic Syndrome in psoriasis: a hospital based cross-sectional study in Central India

Background: Psoriasis is a chronic immune-mediated inflammatory disorder, reported to be associated with obesity, dyslipidaemia and diabetes via common immunological mechanisms. All of these components ultimately increase the risk of metabolic syndrome and cardiovascular morbidities. Aims and Objectives: To assess the association of Metabolic Syndrome (MS) and its components in patients suffering from psoriasis. To study the relationship between the duration and severity of psoriasis and MS. Materials and Methods: A hospital based cross-sectional study was conducted involving 100 adult patients with psoriasis and 100 controls. All participants were evaluated forpsoriasis and the components of MS. Psoriasis was categorized as mild, moderate and severe based on Psoriasis Area and Severity Index (PASI) (<7, 8–12 and >12, respectively). In all patients and controls, body mass index was calculated, blood pressure and waist circumference were measured and fasting blood sugar and lipid profile were estimated. Results: In the present study, a higher prevalence of MS in Psoriasis patients than in controls (38% v/s 23%) was observed. Psoriatic patients had higher prevalence of hypertension (36% v/s 14%). It can be concluded that association of MS and psoriasis is independent of the type, duration and severity of psoriasis. Conclusion: The present study suggests that subjects with psoriasis present a greater risk of MS and should trigger a higher clinical suspicion for their co-existence. Psoriasis is a systemic disease with significant morbidity and mortality. This study emphasizes the critical need for providers to screen psoriasis patients for early diagnosis and treatment of associated MS. However, more number of large population based cohort studies are required to establish stronger association between psoriasis and MS

Study of dermatological manifestations in neonates attending a tertiary healthcare centre

Background: Skin of newborn can be a considerable source of information about infant’s health and promptly alerts the physician regarding serious diseases. Since neonatal skin and adult skin differ in physiology and pathological presentations, neonatal skin conditions require special attention. Aim: This study highlights the pattern of various neonatal dermatoses in a tertiary care healthcare center. Materials & Methods: The study was conducted in a tertiary healthcare center where 804 neonates delivered/visiting in the institute were included and observed for any kind of dermatological condition. After taking informed consent from parents, thorough examination was done and observations were noted in a preset proforma. Result: Among the patient in our study, males were 54% (324) and females were 46% (276). Overall most common neonatal dermatoses was desquamation of skin (396, 66%) followed by Mongolian spots(390,65%), Erythema toxicum neonatorum (162,27%), sebaceous gland hyperplasia (120,20%). The most common dermatoses in full term neonates were Mongolian spots(354,73.8%), desquamation of skin (324,67.5%), ETN(162,33.8%) while in pre term babies, desquamation of skin was followed by SGH, physiological jaundice, Impetigo and Mongolian spots. (24,26.7% each). Conclusion: Skin disorders in neonates require considerable knowledge of pediatric medicine. Hence, the study assesses the pattern of neonatal dermatoses