Study of subsynchronous resonance and its countermeasure using static VAR compensator

This project includes the study of Subsynchronous resonance (SSR) phenomenon which occurs in a power system having series capacitor compensated transmission line. Static VAR compensators can be used to damp SSR oscillations besides controlling the system voltage. The First IEEE benchmark model and eigenvalue techniques are applied in the project to study the behavior of turbo-generator connected to the series compensated transmission line

A study comparing non-gestational diabetes mellitus and gestational diabetes mellitus in antenatal patients in a tertiary care center

Background: Gestational diabetes mellitus is defined as any glucose intolerance with the onset or first recognition during pregnancy. Objectives of this study were to diagnose cases of GDM by screening with DIPSI criteria at less than 28 weeks. And observation and comparison of maternal and perinatal outcome in women diagnosed of GDM in less than 20 weeks and at 24-28 weeks.Methods: This was the prospective analytical study conducted in the department of obstetrics and gynecology for one year in Muzaffarnagar medical college and Hospital. After history taking, clinical and obstetrics examination 1503 antenatal patients of less than 28 weeks were enrolled underwent screening with DIPSI criteria. Out of which 80 patients with abnormal OGTT of gestational age less than 20 weeks and 69 patients with abnormal OGTT of gestational age 24 -28 weeks.Results: In early diagnosed GDM group alive and healthy babies were slightly lower as compared with late diagnosed GDM group.Conclusions: The diagnosis of GDM gives us an opportunity in identifying individuals who will be benefitted by early therapeutic intervention with diet, exercise, and normalizing the weight to delay or prevent the onset of the disease

A sociological study of the family influences, educational experiences and aspirations of a group of South African Indian female students at the University of Durban-Westville.

Thesis (M.Ed.) - University of Durban-Westville, 1995Abstract not available

Intruders in the sacred grove of science? : a critical analysis of women academics' participation in research in the humanities and social sciences.

Thesis (Ph.D.) - University of Durban-Westville, 2000.Knowledge production or research in South Africa, as elsewhere in the world, does not occur within 'innocent' spaces devoid of personal, social, political, economic and cultural contexts. Research in the Humanities and Social Sciences has been largely the domain of white, male academics operating within positivistic, western, or eurocentric paradigms that have consequently cast all differing modes of knowledge production as 'other'. Research has been 'normalised' within particular frames of reference that have often served to marginalize knowledge production emanating from other contexts such as a feminist perspective or a black perspective. This thesis presents a critical analysis of the participation of women academics in research in the Humanities and Social Sciences in South Africa. I argue in this study that the discourses and practices of the academy have traditionally operated to marginalize, and continues to marginalize women effectively excluding them from the arena of research. Whilst there are many studies that have been conducted investigating women in academia, the emphases have been essentially on establishing baseline data such as the numbers and positions women occupy and explanations for the situations that exist. There are, however, very few studies that have extended the analysis to focus on women as researchers and knowledge producers within academia as is the case with this study. I also advance the analyses by arguing for a shift from the widely accepted conceptions that cast women academics as the problem and focus attention instead on the often hostile culture or climate of academia. I argue further that the historical exclusion of women and more especially black women, from the production of knowledge or research has contributed to the exclusion of women from positions of power in the social, cultural, political, economic and academic contexts. My own passion for these issues is directly linked to a conviction that in its public absence, and in the assumption that knowledge about gender is largely irrelevant to the possibility of social justice, lies some of the deep roots of women's complex degradations. This study grew out of my participation in the former Centre for Science Development's (now part of the National Research Foundation) audit of women academics and researchers in the Humanities and Social Sciences in South Africa and was carried out in three phases. The first phase entailed a secondary analysis of the audit data, drawing comparisons between the national findings and the findings for the province of KwaZulu-Natal. Besides conducting a general analysis the data was also disaggregated according to the historically designated racial categories to establish how black women, in particular, were faring. Having established a statistical picture, the second phase was concerned with exploring the qualitative understandings of women academics in research, through the eyes of six black women academics from KwaZulu-Natal. The six women in the study were selected from the University of Durban-Westville, the University of Zululand (both historically disadvantaged institutions) and the University of Natal (a historically advantaged institution). Although it is my contention that all research is necessarily autobiographical, the third phase of the study turned my 'subtext' of being the researcher who is simultaneously 'other' into 'text'. In the autobiographical data I author and reflect on my own experiences as an academic and researcher who is 'other'. Conducted in a style that challenges the mainstream or what is described as 'male-stream' conventions and understandings of research practice, I inscribe the personal into the 'scientific' by employing an autobiographical, feminist 'gaze' throughout this study. The narrative style of communicating parts of the study to the audience, and my attempt to blur the divide between researcher and researched, express a significant feminist desire to infuse the generic aspects of feminist theory, feminist methodology, feminist practice and feminist politics into each other. Finally the insights gained from this study about the general participation of women academics in research and more especially, the position and experiences of black women academics, including myself, achieve many objectives. Not only does it provide baseline information for the province of KwaZulu-Natal in relation to the national trends but also serves to unpack this baseline information with respect to the historically designated racial categories and deepens our understandings of the problems through insights into the day-to-day lived experiences of black women in particular. All of which are integral to informing equity and redress initiatives designed to bring about transformation and democratisation in the arena of research in the humanities and social sciences

Prevalence and predictors of metabolic syndrome in women with polycystic ovarian syndrome: a study from Southern India

Background: Metabolic syndrome (MBS) is a common disorder and is thought to be highly prevalent in polycystic ovarian syndrome (PCOS). The objectives were to find out the prevalence and predictors of metabolic syndrome in women with PCOS.Methods: Forty five women diagnosed with PCOS, underwent clinical and laboratory assessments for the diagnosis of metabolic syndrome, as per modified National Cholesterol Education Program’s Adult Treatment Panel III (NCEP ATP III criteria).Results: Twenty four (53.3%) subjects had metabolic syndrome. The prevalence of individual components of the metabolic syndrome among PCOS patients were: waist circumference ≥80 cm in 36 (86.6%), High Density Lipoprotein (HDL-C) less than 50 mg/dl in 42 (93.3%), triglycerides ≥150 mg/dl in 17 (37.8%), blood pressure ≥130/85 mmHg in 7 (15.6%), and fasting plasma glucose ≥100 mg/dl in 13 (28.8%). Subjects with MBS had significantly higher BMI compared to those without (P = 0.039). However, fasting insulin and free testosterone levels did not differ significantly between subjects with and without MBS.Conclusions: The metabolic syndrome and its individual components, waist circumference ≥80 cm in particular were found to be common among PCOS patients in this study. This along with high BMI being significantly associated with MBS suggests immediate need of interventions like lifestyle changes for prevention of MBS and other cardiovascular diseases. Also, as dyslipidemia was more common than impaired fasting glucose among PCOS patients, finding of one risk factor should prompt the clinician to search for other risk factors

Prevalence of neurological malformation in newborns at a tertiary care center in Rajasthan, India

Introduction: Many newborns die every year due to various congenital anomalies and those who survive, suffer from long-term morbidity. To deal with birth defects, a large proportion of health resources and workforce is required. Among the various congenital anomalies, neurological birth defects are the leading type. Objective: The objective of the study was to document the epidemiological features and prevalence of congenital neurological anomalies in rural areas. Materials and Methods: This retrospective study was conducted in the department of pediatric of a medical college of Rajasthan. The study population included live births born in our institution between 1990 and 2018. A register was maintained after delivery to document the particulars of neonates with a congenital birth defect and their mothers. We had taken neonatal record from this register and analyzed the data of the past 28 years, retrospectively. Results: Of 241,848 live births, 6623 cases were identified with a primary diagnosis of one or more congenital anomalies giving a prevalence rate of 274/10,000 live births (95% confidence interval [CI]: 262.2–285.8). Anomalies of the nervous system were the second common defects, accounting for 19.95% of the birth defects just after the heart disease anomalies (21.65%). Neurological anomalies were diagnosed in 1321 neonates. The prevalence of neurological anomalies was 54.62/10,000 live births (95% CI: 49.75–59.49). The most common neurological anomaly was myelomeningocele/meningocele (spina bifida cystic) found in 64.87% of cases followed by Chiari malformation (7.72%), encephalocele (6.89%), microcephaly (6.88%), hydrocephalous (1.43%), and spina bifida occulta (1.43%). Conclusion: Neurological anomalies were among common congenital anomalies and considerable cause of mortality and morbidity. Myelomeningocele/meningocele (spina bifida cystic) was the most common neurological anomaly

Interferon Alpha Characterization and Its Comparative Expression in PBM Cells of Capra hircus and Antelope cervicapra Cultured in the Presence of TLR9 Agonist

TLR9 plays pivotal role in innate immune responses through upregulation of costimulatory molecules and induction of proinflammatory cytokines like type I interferons including interferon alpha (IFNA). The present study characterized IFNA cDNA and predicted protein sequences in goat and black buck. Response of the PBM cells to TLR9 agonist CpG ODN C and Phorbol Myristate Acetate (PMA) was evaluated by realtime PCR. IFNA coding sequences were amplified from leukocyte cDNA and cloned in pGEMT-easy vector for nucleotide sequencing. Sequence analysis revealed 570 bp, IFNA ORF encoding 189 amino acids in goat and black buck. Black buck and goat IFNA has 92.1% to 94.7% and 93% to 95.6% similarity at nucleotide level, 86.3% to 89.5% and 70.9% to 91.6% identity at amino acid level with other ruminants, respectively. Nonsynonymous substitutions exceeding synonymous substitutions indicated IFNA evolved through positive selection among ruminants. In spite of lower total leukocyte count, the innate immune cells like monocytes and neutrophils were more in black buck compared to goat. In addition, CpG ODN C-stimulated PBM cells revealed raised IFNA transcript in black buck than goat. These findings indicate sturdy genetically governed immune system in wild antelope black buck compared to domestic ruminant goat

A prospective key informant surveillance system to measure maternal mortality – findings from indigenous populations in Jharkhand and Orissa, India

In places with poor vital registration, measurement of maternal mortality and monitoring the impact of interventions on maternal mortality is difficult and seldom undertaken. Mortality ratios are often estimated and policy decisions made without robust evidence. This paper presents a prospective key informant system to measure maternal mortality and the initial findings from the system

Eff ect of participatory women’s groups facilitated by Accredited Social Health Activists on birth outcomes in rural eastern India: a cluster-randomised controlled trial

Background A quarter of the world’s neonatal deaths and 15% of maternal deaths happen in India. Few community-based strategies to improve maternal and newborn health have been tested through the country’s government-approved Accredited Social Health Activists (ASHAs). We aimed to test the eff ect of participatory women’s groups facilitated by ASHAs on birth outcomes, including neonatal mortality. Methods In this cluster-randomised controlled trial of a community intervention to improve maternal and newborn health, we randomly assigned (1:1) geographical clusters in rural Jharkhand and Odisha, eastern India to intervention (participatory women’s groups) or control (no women’s groups). Study participants were women of reproductive age (15–49 years) who gave birth between Sept 1, 2009, and Dec 31, 2012. In the intervention group, ASHAs supported women’s groups through a participatory learning and action meeting cycle. Groups discussed and prioritised maternal and newborn health problems, identifi ed strategies to address them, implemented the strategies, and assessed their progress. We identifi ed births, stillbirths, and neonatal deaths, and interviewed mothers 6 weeks after delivery. The primary outcome was neonatal mortality over a 2 year follow up. Analyses were by intention to treat. This trial is registered with ISRCTN, number ISRCTN31567106. Findings Between September, 2009, and December, 2012, we randomly assigned 30 clusters (estimated population 156 519) to intervention (15 clusters, estimated population n=82 702) or control (15 clusters, n=73 817). During the follow-up period (Jan 1, 2011, to Dec 31, 2012), we identifi ed 3700 births in the intervention group and 3519 in the control group. One intervention cluster was lost to follow up. The neonatal mortality rate during this period was 30 per 1000 livebirths in the intervention group and 44 per 1000 livebirths in the control group (odds ratio [OR] 0.69, 95% CI 0·53–0·89). Interpretation ASHAs can successfully reduce neonatal mortality through participatory meetings with women’s groups. This is a scalable community-based approach to improving neonatal survival in rural, underserved areas of India

Effectiveness of a Yoga-Based Lifestyle Protocol (YLP) in Preventing Diabetes in a High-Risk Indian Cohort: A Multicenter Cluster-Randomized Controlled Trial (NMB-Trial)

IntroductionThough several lines of evidence support the utility of yoga-based interventions in diabetes prevention, most of these studies have been limited by methodological issues, primarily sample size inadequacy. Hence, we tested the effectiveness of yoga-based lifestyle intervention against diabetes risk reduction in multicentre, large community settings of India, through a single-blind cluster-randomized controlled trial, Niyantrita Madhumeha Bharat Abhiyan (NMB). Research Design and MethodsNMB-trial is a multicentre cluster-randomized trial conducted in 80 clusters [composed of rural units (villages) and urban units (Census Enumeration Blocks)] randomly assigned in a 1:1 ratio to intervention and control groups. Participants were individuals (age, 20–70 years) with prediabetes (blood HbA1c values in the range of 5.7–6.4%) and IDRS ≥ 60. The intervention included the practice of yoga-based lifestyle modification protocol (YLP) for 9 consecutive days, followed by daily home and weekly supervised practices for 3 months. The control cluster received standard of care advice for diabetes prevention. Statistical analyses were performed on an intention-to-treat basis, using available and imputed datasets. The primary outcome was the conversion from prediabetes to diabetes after the YLP intervention of 3 months (diagnosed based upon HbA1c cutoff >6.5%). Secondary outcome included regression to normoglycemia with HbA1c <5.7%.ResultsA total of 3380 (75.96%) participants were followed up at 3 months. At 3 months post-intervention, overall, diabetes developed in 726 (21.44%) participants. YLP was found to be significantly effective in halting progression to diabetes as compared to standard of care; adjusted RRR was 63.81(95% CI = 56.55–69.85). The YLP also accelerated regression to normoglycemia [adjusted Odds Ratio (adjOR) = 1.20 (95% CI, 1.02–1.43)]. Importantly, younger participants (≤40 years) were found to regress to normoglycemia more effectively than the older participants Pinteraction<0.001. ConclusionBased on the significant risk reduction derived from the large sample size, and the carefully designed randomized yoga-based intervention on high-risk populations, the study is a preliminary but strong proof-of-concept for yoga as a potential lifestyle-based treatment to curb the epidemic of diabetes. The observed findings also indicate a potential of YLP for diabetes prevention in low/moderate risk profile individuals that needs large-scale validation.Trial RegistrationClinical Trial Registration Number: CTRI/2018/03/012804