5,967 research outputs found
Robust, Recognizable and Legitimate: Strengthening India's Appliance Efficiency Standards and Labels Through Greater Civil Society Involvement
Residential use accounts for 14 percent of global energy consumption. Appliance standards alone could achieve 17 percent energy reductions in the residential sector. Although appliance efficiency standards and labeling programs (AES&L) aim to influence consumer behavior, consumers and civil society often play a limited role in the design, implementation, and monitoring of these programs. This report considers the contribution that civil society organizations can make at each stage of an appliance efficiency standards and labeling program (AES&L), based on experiences in 10 developed and developing countries
Learners on the periphery: lurkers as invisible learners
Lurkers, who are also known as silent learners, observers, browsers, read-only participants, vicarious learners, free-riders, witness learners, or legitimate peripheral participants (our preferred term), tend to be hard to track in a course because of their near invisibility. We decided to address this issue and to examine the perceptions that lurkers have of their behaviour by looking at one specific online learning course: CLMOOC. In order to do this, we used a mixed methods approach and collected our data via social network analysis, online questionnaires, and observations, including definitions from the lurkers of what they thought lurking was. We then analysed the data by using social network and content analyses and interpreted the research findings using the concept Community of Practice, with the Pareto Principle used to delimit types of learner. Our research findings revealed that lurking is a complex behaviour, or set of behaviours, and there isn’t one sole reason why lurkers act the ways that they do in their respective communities. We concluded that for a more participatory community the more active, experienced or visible community members could develop strategies to encourage lurkers to become more active and to make the journey from the periphery to the core of the community
Ethnicity and the Mental Health Act 1983
Background Black and minority ethnic (BME) patients are disproportionately detained under the Mental Health Act 1983. There has been no systematic exploration of differences within and between ethnic groups, nor of the explanations put forward for this excess.
Aims To systematically review detention and ethnicity, with meta-analyses of detention rates for BME groups, and to explore the explanations offered for ethnic differences in detention rates.
Method Literature search and meta-analysis. Explanations offered were categorised, supporting literature was accessed and the strength of the evidence evaluated.
Results In all, 49 studies met inclusion criteria; of these, 19 were included in the meta-analyses. Compared with White patients, Black patients were 3.83 times, BME patients 3.35 times and Asian patients 2.06 times more likely to be detained. The most common explanations related to misdiagnosis and discrimination against BME patients, higher incidence of psychosis and differences in illness expression. Many explanations, including that of racism within mental health services, were not supported by clear evidence.
Conclusions Although BME status predicts psychiatric detention in the UK, most explanations offered for the excess detention of BME patients are largely unsupported
Detection and emotional evaluation of an electric vehicle’s exterior sound in a simulated environment
Electric vehicles are quiet at low speeds and thus potentially pose a threat to pedestrians’ safety. Laws are formulating worldwide that mandate these vehicles emit sounds to alert the pedestrians of the vehicles’ approach. It is necessary that these sounds promote a positive perception of the vehicle brand, and understanding their impact on soundscapes is also important. Detection time of the vehicle sounds is an important measure to assess pedestrians’ safety. Emotional evaluation of these sounds influences assessment of the vehicle brand. Laboratory simulation is a new approach for evaluating exterior automotive sounds. This study describes the implementation of laboratory simulation to compare the detection time and emotional evaluation of artificial sounds for an electric vehicle. An Exterior
Sound Simulator simulated audio-visual stimuli of an electric car passing a crossroad of a virtual town at 4.47 ms-1 (10 mph), from the perspective of a pedestrian standing at the crossroad. In this environment, 15 sounds were tested using experiments where participants detected the car and evaluated its sound using perceptual dimensions. Results show that these sounds vary significantly in their detection times and emotional evaluations, but crucially that traditional metrics like dB(A) do not always relate to the detection of these sounds. Detection time and emotional evaluation do not have significant correlation. Hence, sounds of a vehicle could be detected
quickly, but may portray negative perceptions of the vehicle. Simulation provides a means to more fully evaluate potential electric vehicle sounds against the competing criteria
A theoretical analysis of secondary structural characteristics of anticancer peptides
Here, cluster analysis showed that a database of 158 peptides formed 21 clusters based on net positive charge, hydrophobicity and amphiphilicity. In general these clusters showed similar median toxicities (p = 0.176) against eukaryotic cell lines and no single combination of these properties was found optimal for efficacy. The database contained 14 peptides, which showed selectivity for tumour cell lines only (ACPCT), 123 peptides with general toxicity to eukaryotic cells (ACPGT) and 21 inactive peptides (ACPI). Hydrophobic arc size analysis showed that there was no significant difference across the datasets. Even though there was no correlation there was no correlation observed, peptides with wide hydrophobic arcs (> 270°) appeared less toxic. Extended hydrophobic moment plot analysis predicted that over 50% of ACPCT and ACPGT peptides would be surface active, which led to the suggestion that amphiphilicity is a key driver of the membrane interactions for these peptides but probably plays a role in their efficacy rather than their selectivity. This analysis also predicted that only 14% of ACPCT peptides compared to 45% of ACPGT peptides were candidates for tilted peptide formation. This implies that those peptides with non-specific activity may have a tendency towards the utilisation of membrane disruptive structures such as tilt peptides which led to the suggestion that the absence of this structure may support cancer cell selectivity. However, these analyses predicted that ACPI peptides, which possess no anticancer activity, would also form surface active and tilted a-helices, clearly showing that other factors are involved in determining the efficacy and selectivity of ACPs
Geography of Pilgrimage with Special Reference to Islam
Pilgrimage is a spiritual journey during which pilgrims have a religious experience and feel connected to the faith's spiritual legacy. The sacred sites are the spiritual home for pilgrims which they have read and heard about but never visited or experienced before. With little attention paid to the Islamic pilgrimage, especially by geographers, this review paper is an attempt to provide an overview of the subject matter and seek to put forward possible future research directions. This paper provides a systematic description of pilgrimage in Islam by reviewing the literature on the subject, analysing the definitions, characteristics, processes, classification and authorisation of pilgrimage in general followed by an overview of Islamic pilgrimage, that is, Ziyarat by defining key terms, discussing the typology and exploring the neglected dimensions in Islamic pilgrimage studies. The study has brought the relics and saints venerated in the Muslim world into focus, which are the essential causes for the origin and continuation of the Ziyarat tradition. It also points out the different occasions and reasons for performing popular pilgrimage in Islam. And lastly, it discusses the future research dimensions of Islamic pilgrimage
Dorsal Eye Selector Pannier (pnr) Suppresses the Eye Fate to Define Dorsal Margin of the Drosophila Eye
Axial patterning is crucial for organogenesis. During Drosophila eye development, dorso-ventral (DV) axis determination is the first lineage restriction event. The eye primordium begins with a default ventral fate, on which the dorsal eye fate is established by expression of the GATA-1 transcription factor pannier (pnr). Earlier, it was suggested that loss of pnr function induces enlargement in the dorsal eye due to ectopic equator formation. Interestingly, we found that in addition to regulating DV patterning, pnr suppresses the eye fate by downregulating the core retinal determination genes eyes absent (eya), sine oculis (so) and dacshund (dac) to define the dorsal eye margin. We found that pnr acts downstream of Ey and affect the retinal determination pathway by suppressing eya. Further analysis of the “eye suppression” function of pnr revealed that this function is likely mediated through suppression of the homeotic gene teashirt (tsh) and is independent of homothorax (hth), a negative regulator of eye. Pnr expression is restricted to the peripodial membrane on the dorsal eye margin, which gives rise to head structures around the eye, and pnr is not expressed in the eye disc proper that forms the retina. Thus, pnr has dual function, during early developmental stages pnr is involved in axial patterning whereas later it promotes the head specific fate. These studies will help in understanding the developmental regulation of boundary formation of the eye field on the dorsal eye margin
North Medford High School NASA High Altitude Balloon Project
We are one of 57 teams across the nation that participated in the NASA High Altitude Balloon Project. The overall goal of the project was to capture and live stream the Great American Eclipse from 80,000-100,000 feet. As one of the few high school teams it has given us an unique perspective. Not only did we launch the common NASA payload, our team designed, engineered, and constructed our own payload named Tornado. Our team\u27s additional goals included photographing the umbra, and learning how UVA, UVB, gamma radiation, and other atmospheric conditions are affected during a solar eclipse. We met all of our team goals, as well as the NASA goals. In addition, we also participated in a project conducted by Cornell University; this project involved attaching bacteria samples to our payload in order to test their survival in the upper atmosphere
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