ВЛИЯНИЕ ТИПА ЦЕОЛИТА КАК КОМПОНЕНТА КОМПОЗИТНОГО КОБАЛЬТОВОГО КАТАЛИЗАТОРА НА СОСТАВ ПРОДУКТОВ СИНТЕЗА ФИШЕРА–ТРОПША

The dependence of zeolite type in a composite catalyst, namely structural features, presence of alkali metal cation and total acidity, on the composition of Fischer-Tropsch product has been shown in the article. Highly dispersed skeleton cobalt (Raney cobalt) was used as active metal. It was found that the presence of zeolite in Hform in the composition of the catalyst results in the formation of a larger number of unsaturated and branched hydrocarbons. The cobalt composite catalyst based on HBeta zeolite is more active and more productive in the synthesis of C<sup>5+</sup> hydrocarbons from CO and H<sub>2</sub> than the catalyst based on KA zeolite. Assumptions of the role of zeolite acid sites in secondary transformations of hydrocarbons produced from CO and H<sub>2</sub> on skeleton cobalt were done.В статье исследована зависимость состава продуктов синтеза Фишера–Тропша от типа цеолита в составе композитного катализатора. При анализе результатов учтены струк-турные особенности, наличие катиона щелочного металла, общая кислотность. В качестве активного металла использовали мелкодисперсный скелетный кобальт. Установлено, что в присутствии цеолита в Н-форме образуется большее количество ненасыщенных и разветвленных углеводородов. Кобальтовый композитный катализатор на основе цеолита HBeta активнее и производительнее в синтезе углеводородов С5+ из СО и Н2, чем катализатор на основе цеолита КА. Сделаны предположения о роли кислотных центров цеолита во вторичных превращениях угле-водородов, образовавшихся из СО и Н2 на скелетном кобальте

Glycogen Synthase Kinase 3 (GSK3) Inhibitor, SB-216763, Promotes Pluripotency in Mouse Embryonic Stem Cells

Canonical Wnt/β-catenin signaling has been suggested to promote self-renewal of pluripotent mouse and human embryonic stem cells. Here, we show that SB-216763, a glycogen synthase kinase-3 (GSK3) inhibitor, can maintain mouse embryonic stem cells (mESCs) in a pluripotent state in the absence of exogenous leukemia inhibitory factor (LIF) when cultured on mouse embryonic fibroblasts (MEFs). MESCs maintained with SB-216763 for one month were morphologically indistinguishable from LIF-treated mESCs and expressed pluripotent-specific genes Oct4, Sox2, and Nanog. Furthermore, Nanog immunostaining was more homogenous in SB-216763-treated colonies compared to LIF. Embryoid bodies (EBs) prepared from these mESCs expressed early-stage markers for all three germ layers, and could efficiently differentiate into cardiac-like cells and MAP2-immunoreactive neurons. To our knowledge, SB-216763 is the first GSK3 inhibitor that can promote self-renewal of mESC co-cultured with MEFs for more than two months

The influence of zeolite type in composite cobalt catalyst on the Fischer–Tropsch synthesis product composition

The dependence of zeolite type in a composite catalyst, namely structural features, presence of alkali metal cation and total acidity, on the composition of Fischer-Tropsch product has been shown in the article. Highly dispersed skeleton cobalt (Raney cobalt) was used as active metal. It was found that the presence of zeolite in Hform in the composition of the catalyst results in the formation of a larger number of unsaturated and branched hydrocarbons. The cobalt composite catalyst based on HBeta zeolite is more active and more productive in the synthesis of C<sup>5+</sup> hydrocarbons from CO and H<sub>2</sub> than the catalyst based on KA zeolite. Assumptions of the role of zeolite acid sites in secondary transformations of hydrocarbons produced from CO and H<sub>2</sub> on skeleton cobalt were done