2-Chloro-N-(4-meth­oxy­phen­yl)benzamide

In the title compound, C14H12ClNO2, the chloro- and meth­oxy-substituted benzene rings are close to orthogonal [dihedral angle = 79.20 (3)°]. These rings also make angles of 45.9 (3) and 33.5 (3)° with the amide –CONH– unit. The meth­oxy substituent lies close to the meth­oxy­benzene ring plane, with a maximum deviation of 0.142 (3) Å for the methyl C atom. The N—H bond is anti to the 2-chloro substituent of the aniline ring. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds form C(4) chains augmented by a weak C—H⋯O inter­action involving an ortho H atom of the meth­oxy benzene ring that generates an R 2 1(6) motif. The chains stack the mol­ecules into columns down the b axis. Adjacent columns are linked by additional C—H⋯O and C—H⋯π contacts, generating a three-dimensional network

Oral History of Glenn Presley

Written interview with Glenn Scott Presley, 1996 recipient of the Christa McAuliffe award.https://scholars.fhsu.edu/ors/1269/thumbnail.jp

2-[(N-Benzyl-4-methyl­benzene­sul­fon­amido)meth­yl]pyridinium nitrate

In the title compound, C20H21N2O2S+·NO3 −, the dihedral angle between the pyridinium and phenyl rings is 81.77 (19)°, that between the pyridinium and tolyl rings is 1.36 (18)°, and that between the phenyl and tolyl rings is 82.69 (19)°. In the crystal, the components are linked by strong charge-assisted bifurcated N+—H⋯(O,O) hydrogen bonds and the packing is consolidated by numerous weak C—H⋯O bonds and π–π stacking inter­actions [for the latter, centroid–centroid separation = 3.868 (2) Å]

(E)-4-Bromo-N-(2,4-dimethoxy­benzyl­idene)aniline

The title Schiff base compound, C15H14BrNO2, adopts an E configuration with respect to the C=N bond. The C and O atoms of the two meth­oxy substituents lie very close to the dimethoxy­phenyl ring plane [maximum deviation = 0.17 (1) Å]. The dihedral angle between the two aromatic rings is 43.69 (16)°, while the plane through the central C—C=N—C system is inclined at 10.6 (6)° to the dimethoxy­phenyl ring and 34.6 (3)° to the bromo­phenyl ring. In the crystal structure, each mol­ecule is involved in the formation of two inversion-related dimers through weak C—H⋯N and C—H⋯O inter­actions, respectively. These contacts link the mol­ecules into independent rows parallel to the b axis

1-(2-Fluoro­phen­yl)-6,7-dimethoxy­isochroman

In the title compound, C17H17FO3, the benzene ring of the isochroman unit is inclined at 84.96 (7)° to the fluoro­benzene ring plane, and the pyran ring adopts a half-boat conformation. In the crystal structure, C—H⋯O hydrogen bonds link mol­ecules into rows along the c axis, while C—H⋯O inter­actions and C—H⋯F hydrogen bonds to the fluorine acceptor stack the mol­ecules down the b axis. In addition, the crystal structure exhibits a weak C—H⋯π inter­action between a methyl H atom of the meth­oxy group and the dimethoxy­benzene ring of an adjacent mol­ecule

Mutation of Arabidopsis SPLICEOSOMAL TIMEKEEPER LOCUS1 Causes Circadian Clock Defects

The circadian clock plays a crucial role in coordinating plant metabolic and physiological functions with predictable environmental variables, such as dusk and dawn, while also modulating responses to biotic and abiotic challenges. Much of the initial characterization of the circadian system has focused on transcriptional initiation, but it is now apparent that considerable regulation is exerted after this key regulatory step. Transcript processing, protein stability, and cofactor availability have all been reported to influence circadian rhythms in a variety of species. We used a genetic screen to identify a mutation within a putative RNA binding protein (SPLICEOSOMAL TIMEKEEPER LOCUS1 [STIPL1]) that induces a long circadian period phenotype under constant conditions. STIPL1 is a homolog of the spliceosomal proteins TFP11 (Homo sapiens) and Ntr1p (Saccharomyces cerevisiae) involved in spliceosome disassembly. Analysis of general and alternative splicing using a high-resolution RT-PCR system revealed that mutation of this protein causes less efficient splicing of most but not all of the introns analyzed. In particular, the altered accumulation of circadian-associated transcripts may contribute to the observed mutant phenotype. Interestingly, mutation of a close homolog of STIPL1, STIP-LIKE2, does not cause a circadian phenotype, which suggests divergence in function between these family members. Our work highlights the importance of posttranscriptional control within the clock mechanism. © 2012 American Society of Plant Biologists. All rights reserved

The gifts of the Roland: the old French Gui de Bourgogne

This piece explores the dialectical relation between the Old French epic, Gui de Bourgogne, and one of its key models, the Roland tradition. The tension between the two works is thematicised in the rivalry between the two generations of heroes: that of Roland and Olivier on the one hand and then a younger cohort of French warriors, led by Gui, who have grown up in the absence of their fathers. The essay examines how personal, social and economic interactions in the poem reflect an ambivalence partly reflective of a crippling sense of literary and historical debt to the giants of the epic tradition

The gifts of the Roland: the old French Gui de Bourgogne

This piece explores the dialectical relation between the Old French epic, Gui de Bourgogne, and one of its key models, the Roland tradition. The tension between the two works is thematicised in the rivalry between the two generations of heroes: that of Roland and Olivier on the one hand and then a younger cohort of French warriors, led by Gui, who have grown up in the absence of their fathers. The essay examines how personal, social and economic interactions in the poem reflect an ambivalence partly reflective of a crippling sense of literary and historical debt to the giants of the epic tradition

A monoclinic polymorph of N-(3-chloro­phen­yl)benzamide

The title compound, C13H10ClNO, (I), is a polymorph of the structure, (II), first reported by Gowda et al. [Acta Cryst. (2008), E64, o462]. In the original report, the compound crystallized in the ortho­rhom­bic space group Pbca (Z = 8), whereas the structure reported here is monoclinic P21/c (Z = 4). The principal difference between the two forms lies in the relative orientations of the phenyl and benzene rings [dihedral angle = 8.90 (13)° for (I) and 61.0 (1)° for (II)]. The inclination of the amide –CONH– units to the benzoyl ring is more similar [15.8 (7)° for (I) and 18.2 (2)° for (II)]. In both forms, the N—H bonds are anti to the 3-chloro substituents of the aniline rings. In the crystal, inter­molecular N—H⋯O hydrogen bonds form C(4) chains along c. These chains are bolstered by weak C—H⋯O inter­actions that generate R 2 1(6) and R 2 1(7) ring motifs

Ethyl 5-hy­droxy-6-oxo-4-phenyl-5,6-dihydro-4H-cyclo­penta­[b]thio­phene-5-carboxyl­ate

In the title mol­ecule, C16H14O4S, the dihydro­cyclo­penta­thio­phenone ring system is almost planar, with an r.m.s. deviation of 0.060 Å from the best fit plane through all nine non-H atoms. The cyclo­penta­none ring adopts a severely flattened envelope conformation with the C atom carrying the OH and ethylcarboxylate substituents at the flap. This atom lies only 0.185 (3) Å from the plane through the other four C atoms. The phenyl substituent is inclined at 43.37 (5)° to the dihydro­cyclo­penta­thio­phenone mean plane. In the crystal, mol­ecules are linked by pairs of O—H⋯O hydrogen bonds, forming inversion dimers with R 2 2(10) ring motifs. Weak C—H⋯O hydrogen bonds also link mol­ecules into chains along c, while an approximately orthogonal set of C—H⋯O contacts form chains along b, resulting in layers lying parallel to (100). Inversion dimers also form through weaker R 2 2(12) C—H⋯S contacts, which combine with C—H⋯O contacts to form stacks along b