10 research outputs found
The <i>HMMR</i> locus and breast cancer risk in <i>BRCA1</i> mutation carriers.
- Author
- Abul Islam (716100)
- Adam Lee (395196)
- Alejandro SĂĄnchez-Gracia (42167)
- Alex Miron (716110)
- Alex Murray (395230)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda E. Toland (238696)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Anna Jakubowska (146752)
- Anna Petit (196517)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Ans M. W. van den Ouweland (395407)
- Antoine de Pauw (196753)
- Antoni Berenguer (122672)
- Antonio GĂłmez (716114)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Beth Y. Karlan (184236)
- Carol Chu (154167)
- Caroline Seynaeve (95368)
- Cecilia M. Dorfling (395285)
- Chiara Gorrini (60042)
- Chris Jacobs (395409)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Christopher A. Maxwell (196486)
- Clare Oliver (196637)
- Conxi LĂĄzaro (142579)
- Cora M. Aalfs (154133)
- Daniel Barrowdale (395192)
- Daniel Cuadras (489400)
- Danylko Villano (716118)
- Daphne Geschwantler-Kaulich (716109)
- David E. Goldgar (196718)
- David M. O'Malley (716106)
- David Margileth (716113)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elena S. Ratner (716107)
- Elisabeth J. van Rensburg (716111)
- Emma McCann (395229)
- Enrique Vidal (716115)
- Esther M. John (107266)
- Eva Tornero (403529)
- Evgeny N. Imyanitov (395207)
- Fergus J. Couch (146607)
- Fiona Lalloo (196644)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Francesca Mateo (716101)
- Frans B. L. Hogervorst (146390)
- François Cornelis (260403)
- Gabriella Pichert (69450)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gorka Ruiz de Garibay (535799)
- Gustavo C. Rodriguez (395256)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg J. Plendl (716108)
- Heli Nevanlinna (83762)
- Holger Heyn (126177)
- Huw Dorkins (239925)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Konstantopoulou (387787)
- Irene L. Andrulis (107262)
- Isabel CatalĂ (196512)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier BenĂtez (5648629)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Joan Paterson (716103)
- Johanna Rantala (547040)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julie Cunningham (395292)
- Julio Rozas (42168)
- Juul T. Wijnen (154144)
- Kai-Ren Ong (154173)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- Kelly-Anne A. Phillips (716104)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristiina AittomÀki (89889)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laure Barjhoux (395412)
- Laurent Castera (38087)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Lidia FeliubadalĂł (5662999)
- Lone Sunde (547072)
- Loris Bernard (181285)
- Mads Thomassen (395200)
- Manel Esteller (74345)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Margaret Cook (154156)
- Marie Stenmark-Askmalm (395253)
- Marina J. Corines (716117)
- Marinus J. Blok (395217)
- Marion Fassy-Colcombet (716116)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melanie Léoné (5663005)
- Miguel Angel Pujana (32854)
- Miguel de la Hoya (238670)
- Muy-Kheng Tea (308359)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- NĂșria Bonifaci (196493)
- Olga M. Sinilnikova (196738)
- Orland DĂez (5663002)
- Pablo Librado (716099)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascaline Berthet (395233)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita K. Schmutzler (112064)
- Rob B. van der Luijt (196627)
- Robert L. Nussbaum (263844)
- Rosa B. Barkardottir (238688)
- Sabine Preisler-Adams (395251)
- Sandra Fert Ferrer (196769)
- Sergi Sayols (126193)
- Shan Wang-Gohrke (89910)
- Shani Shimon Paluch (395262)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Stacy R. Nerenstone (716105)
- Steven A. Narod (230773)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Teresa RamĂłn y Cajal (460449)
- Thomas V. Hansen (716102)
- Timothy R. Rebbeck (230766)
- Tom Van Maerken (105035)
- Torben A. Kruse (92928)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yves-Jean Bignon (54433)
- Publication venue
- Publication date
- Field of study
<p>(<b>A</b>) Forest plots showing rs299290 HRs and 95% CIs (retrospective likelihood trend estimation) for participating countries (relatively small sample sets are not shown) ordered by sample size. Left and right panels show results for <i>BRCA1</i> and <i>BRCA2</i> mutation carriers, respectively. The sizes of the rectangles are proportional to the corresponding country/study precision. (<b>B</b>) The rs299290-containing region, including the genes, variation and regulatory evidence mentioned in HMECs. Exons are marked by black-filled rectangles and the direction of transcription is marked by arrows in the genomic structure. The chromosome 5 positions (base pairs (bp)) and linkage disequilibrium structure from Caucasian HapMap individuals are also shown.</p
Potential GxG associated with breast cancer risk in <i>BRCA1/2</i> mutation carriers.
- Author
- Abul Islam (716100)
- Adam Lee (395196)
- Alejandro SĂĄnchez-Gracia (42167)
- Alex Miron (716110)
- Alex Murray (395230)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda E. Toland (238696)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Anna Jakubowska (146752)
- Anna Petit (196517)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Ans M. W. van den Ouweland (395407)
- Antoine de Pauw (196753)
- Antoni Berenguer (122672)
- Antonio GĂłmez (716114)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Beth Y. Karlan (184236)
- Carol Chu (154167)
- Caroline Seynaeve (95368)
- Cecilia M. Dorfling (395285)
- Chiara Gorrini (60042)
- Chris Jacobs (395409)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Christopher A. Maxwell (196486)
- Clare Oliver (196637)
- Conxi LĂĄzaro (142579)
- Cora M. Aalfs (154133)
- Daniel Barrowdale (395192)
- Daniel Cuadras (489400)
- Danylko Villano (716118)
- Daphne Geschwantler-Kaulich (716109)
- David E. Goldgar (196718)
- David M. O'Malley (716106)
- David Margileth (716113)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elena S. Ratner (716107)
- Elisabeth J. van Rensburg (716111)
- Emma McCann (395229)
- Enrique Vidal (716115)
- Esther M. John (107266)
- Eva Tornero (403529)
- Evgeny N. Imyanitov (395207)
- Fergus J. Couch (146607)
- Fiona Lalloo (196644)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Francesca Mateo (716101)
- Frans B. L. Hogervorst (146390)
- François Cornelis (260403)
- Gabriella Pichert (69450)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gorka Ruiz de Garibay (535799)
- Gustavo C. Rodriguez (395256)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg J. Plendl (716108)
- Heli Nevanlinna (83762)
- Holger Heyn (126177)
- Huw Dorkins (239925)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Konstantopoulou (387787)
- Irene L. Andrulis (107262)
- Isabel CatalĂ (196512)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier BenĂtez (5648629)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Joan Paterson (716103)
- Johanna Rantala (547040)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julie Cunningham (395292)
- Julio Rozas (42168)
- Juul T. Wijnen (154144)
- Kai-Ren Ong (154173)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- Kelly-Anne A. Phillips (716104)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristiina AittomÀki (89889)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laure Barjhoux (395412)
- Laurent Castera (38087)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Lidia FeliubadalĂł (5662999)
- Lone Sunde (547072)
- Loris Bernard (181285)
- Mads Thomassen (395200)
- Manel Esteller (74345)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Margaret Cook (154156)
- Marie Stenmark-Askmalm (395253)
- Marina J. Corines (716117)
- Marinus J. Blok (395217)
- Marion Fassy-Colcombet (716116)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melanie Léoné (5663005)
- Miguel Angel Pujana (32854)
- Miguel de la Hoya (238670)
- Muy-Kheng Tea (308359)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- NĂșria Bonifaci (196493)
- Olga M. Sinilnikova (196738)
- Orland DĂez (5663002)
- Pablo Librado (716099)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascaline Berthet (395233)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita K. Schmutzler (112064)
- Rob B. van der Luijt (196627)
- Robert L. Nussbaum (263844)
- Rosa B. Barkardottir (238688)
- Sabine Preisler-Adams (395251)
- Sandra Fert Ferrer (196769)
- Sergi Sayols (126193)
- Shan Wang-Gohrke (89910)
- Shani Shimon Paluch (395262)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Stacy R. Nerenstone (716105)
- Steven A. Narod (230773)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Teresa RamĂłn y Cajal (460449)
- Thomas V. Hansen (716102)
- Timothy R. Rebbeck (230766)
- Tom Van Maerken (105035)
- Torben A. Kruse (92928)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yves-Jean Bignon (54433)
- Publication venue
- Publication date
- Field of study
<p>*Each estimate is derived from the interaction term of a Cox regression model.</p><p>Potential GxG associated with breast cancer risk in <i>BRCA1/2</i> mutation carriers.</p
Gene expression interactions in breast cancer survival.
- Author
- Abul Islam (716100)
- Adam Lee (395196)
- Alejandro SĂĄnchez-Gracia (42167)
- Alex Miron (716110)
- Alex Murray (395230)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda E. Toland (238696)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Anna Jakubowska (146752)
- Anna Petit (196517)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Ans M. W. van den Ouweland (395407)
- Antoine de Pauw (196753)
- Antoni Berenguer (122672)
- Antonio GĂłmez (716114)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Beth Y. Karlan (184236)
- Carol Chu (154167)
- Caroline Seynaeve (95368)
- Cecilia M. Dorfling (395285)
- Chiara Gorrini (60042)
- Chris Jacobs (395409)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Christopher A. Maxwell (196486)
- Clare Oliver (196637)
- Conxi LĂĄzaro (142579)
- Cora M. Aalfs (154133)
- Daniel Barrowdale (395192)
- Daniel Cuadras (489400)
- Danylko Villano (716118)
- Daphne Geschwantler-Kaulich (716109)
- David E. Goldgar (196718)
- David M. O'Malley (716106)
- David Margileth (716113)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elena S. Ratner (716107)
- Elisabeth J. van Rensburg (716111)
- Emma McCann (395229)
- Enrique Vidal (716115)
- Esther M. John (107266)
- Eva Tornero (403529)
- Evgeny N. Imyanitov (395207)
- Fergus J. Couch (146607)
- Fiona Lalloo (196644)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Francesca Mateo (716101)
- Frans B. L. Hogervorst (146390)
- François Cornelis (260403)
- Gabriella Pichert (69450)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gorka Ruiz de Garibay (535799)
- Gustavo C. Rodriguez (395256)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg J. Plendl (716108)
- Heli Nevanlinna (83762)
- Holger Heyn (126177)
- Huw Dorkins (239925)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Konstantopoulou (387787)
- Irene L. Andrulis (107262)
- Isabel CatalĂ (196512)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier BenĂtez (5648629)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Joan Paterson (716103)
- Johanna Rantala (547040)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julie Cunningham (395292)
- Julio Rozas (42168)
- Juul T. Wijnen (154144)
- Kai-Ren Ong (154173)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- Kelly-Anne A. Phillips (716104)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristiina AittomÀki (89889)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laure Barjhoux (395412)
- Laurent Castera (38087)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Lidia FeliubadalĂł (5662999)
- Lone Sunde (547072)
- Loris Bernard (181285)
- Mads Thomassen (395200)
- Manel Esteller (74345)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Margaret Cook (154156)
- Marie Stenmark-Askmalm (395253)
- Marina J. Corines (716117)
- Marinus J. Blok (395217)
- Marion Fassy-Colcombet (716116)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melanie Léoné (5663005)
- Miguel Angel Pujana (32854)
- Miguel de la Hoya (238670)
- Muy-Kheng Tea (308359)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- NĂșria Bonifaci (196493)
- Olga M. Sinilnikova (196738)
- Orland DĂez (5663002)
- Pablo Librado (716099)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascaline Berthet (395233)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita K. Schmutzler (112064)
- Rob B. van der Luijt (196627)
- Robert L. Nussbaum (263844)
- Rosa B. Barkardottir (238688)
- Sabine Preisler-Adams (395251)
- Sandra Fert Ferrer (196769)
- Sergi Sayols (126193)
- Shan Wang-Gohrke (89910)
- Shani Shimon Paluch (395262)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Stacy R. Nerenstone (716105)
- Steven A. Narod (230773)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Teresa RamĂłn y Cajal (460449)
- Thomas V. Hansen (716102)
- Timothy R. Rebbeck (230766)
- Tom Van Maerken (105035)
- Torben A. Kruse (92928)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yves-Jean Bignon (54433)
- Publication venue
- Publication date
- Field of study
<p>(<b>A</b>) KaplanâMeier survival curves based on categorization of <i>HMMR</i> (probe NM_012484) and <i>AURKA</i> (NM_003600) expression in tertiles (low, medium or high expression). For simplicity, only the tertiles for âhighâ <i>AURKA</i> are shown. The tumours with high expression levels for both genes were not those with the poorest prognosis. (<b>B</b>) KaplanâMeier survival curves based on categorization of <i>HMMR</i> (NM_012484) and <i>TUBG1</i> (NM_016437) expression in tertiles (low, medium or high expression). For simplicity, only the tertiles for âhighâ <i>HMMR</i> are shown. The cases with high expression levels for both genes were those with the poorest prognosis.</p
[unknown]
- Author
- Adalgeir Arason (238680)
- Adam Freeman (3437756)
- Alex TeulÄĆ (3437813)
- Alfons Meindl (112058)
- Alice Sigurdson (89952)
- Alice Whittemore (3437711)
- Alicia Beeghly-Fadiel (732867)
- Alison Dunning (10539)
- Amanda Toland (3405350)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew Godwin (811543)
- Angela Cox (76913)
- Anja Rudolph (180618)
- Anna GonzÄÄlez-Neira (3437816)
- Anna Jakubowska (146752)
- Anna Mulligan (3437741)
- Anna Wu (3412982)
- Anne-Lise Borresen-Dale (2697364)
- Annegien Broeks (146385)
- Annelie Liljegren (716112)
- Annika Lindblom (26099)
- Ans van den Ouweland (89937)
- Anthony Swerdlow (146780)
- Antoinette Hollestelle (52748)
- Antonis Antoniou (3405323)
- Arnaud Droit (36418)
- Artitaya Lophatananon (146409)
- Arto Mannermaa (89891)
- Ava Kwong (52115)
- Banu Arun (3405263)
- Barbara Burwinkel (146479)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernd Dworniczak (223446)
- Beth Karlan (233752)
- Brita Arver (395252)
- Carl Blomqvist (83761)
- Caroline Baynes (73973)
- Caroline Seynaeve (95368)
- Carolyn Hendricks (3437744)
- Catherine Phelan (3437717)
- Cecilia Dorfling (3437753)
- Charles Joly Beauparlant (3045228)
- Chen-Yang Shen (146768)
- Chenjie Zeng (1301016)
- Christian Singer (3405338)
- Christine Clarke (3437759)
- Christopher Haiman (120857)
- Chuen Lee (3437720)
- Clare Turnbull (146523)
- Claudine Isaacs (59927)
- Conxi Lazaro (3405329)
- Csilla Szabo (3405290)
- Curtis Olswold (73571)
- Daehee Kang (6451)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- David Goldgar (29053)
- David Hunter (273536)
- David ven den Berg (3074547)
- Debra Frost (154160)
- Diether Lambrechts (101772)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas Easton (25461)
- Drakoulis Yannoukakos (4758)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elinor Sawyer (146459)
- Elizabeth van Rensburg (3405299)
- Elza Khusnutdinova (146583)
- Emily Hallberg (553716)
- Esther John (413149)
- Evgeny Imyanitov (3405275)
- Fabienne Lesueur (10534)
- Fergus Couch (89911)
- Fiona Lalloo (196644)
- Florence Menegaux (146487)
- Francesca Damiola (5331)
- Francois Bacot (2615515)
- Frans Hogervorst (3437729)
- Frederik Marme (3071244)
- Gad Rennert (196538)
- Gaetana Gambino (3437747)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Graham Giles (521929)
- Heli Nevanlinna (83762)
- Henrik Flyger (146491)
- Hermann Brenner (63649)
- Hidemi Ito (181434)
- Hiltrud Brauch (89877)
- Hoda Anton-Culver (3473)
- Ian Campbell (205212)
- Irene Andrulis (547071)
- Irene Konstantopoulou (387787)
- Isabel dos-Santos-Silva (528117)
- Jaana Hartikainen (146589)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Jane Carpenter (3358997)
- Javier Benitez (81758)
- Jeffrey Weitzel (269835)
- Jenny Chang-Claude (23562)
- Jenny Lester (395276)
- Ji-Yeob Choi (181377)
- Jingmei Li (254314)
- Jirong Long (181371)
- Joe Dennis (395193)
- John Hopper (218871)
- Jonine Figueroa (273680)
- Joseph Vijai (102398)
- Judith Brand (664345)
- Judy Garber (59512)
- Julia Knight (34590)
- Julian Peto (146454)
- Jyh-Cherng Yu (146771)
- Kamila Czene (77258)
- Karoline Kuchenbaecker (547036)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine Nathanson (547041)
- Kathleen Claes (203063)
- Kathleen Egan (395483)
- Keitaro Matsuo (73893)
- Kenneth Muir (194882)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kim De Leeneer (203028)
- Kristiina AittomĀki (3437822)
- Kyriaki Michailidou (205130)
- Laima Tihomirova (196713)
- Laura Papi (395245)
- Lesley McGuffog (153865)
- Loic Le Marchand (89925)
- Lothar Haeberle (3437738)
- Mads Thomassen (395200)
- Manjeet Bolla (3412991)
- Manuel Teixeira (3405287)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Maria Kabisch (820179)
- Marina Bermisheva (146574)
- Marjanka Schmidt (3437726)
- Mark Greene (3405302)
- Martha Shrubsole (327487)
- Martine Dumont (553712)
- Mary Daly (3405308)
- Mary Terry (3405278)
- Maya Ghoussaini (58249)
- Melissa Southey (81752)
- Michael Friedlander (55581)
- Michael Jones (204958)
- Michael Kerin (146466)
- Michele Doody (89953)
- Miguel de la Hoya (238670)
- Mikael Hartman (77255)
- Min Lee (247140)
- Minouk Schoemaker (146778)
- Miriam Dwek (553697)
- Montserrat GarcÄÂa-Closas (3412988)
- Muhammad Rashid (2836631)
- Nadege Presneau (11214)
- Nadine Tung (238710)
- Natalia Antonenkova (154010)
- Natalia Bogdanova (89885)
- Nazneen Rahman (146509)
- Norhashimah Hassan (3437732)
- Olufunmilayo Olopade (3405344)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal GuÄĆ nel (3437825)
- Paul Brennan (63967)
- Paul Pharoah (15105)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Peter Fasching (3437714)
- Peter Hillemanns (89884)
- Peter Hulick (433187)
- Peter Kraft (15118)
- Peter SchÄĆșrmann (3437807)
- Phuong Mai (3437750)
- Polly Newcomb (218870)
- Qin Wang (109812)
- Qiuyin Cai (25449)
- Ramunas Janavicius (71877)
- Rita Schmutzler (392062)
- Ritu Salani (3437765)
- Robert Nussbaum (3405335)
- Robert Winqvist (146640)
- Roger Milne (260033)
- Saila Kauppila (553713)
- Sandrine Tchatchou (659187)
- Sara Margolin (146586)
- Saundra Buys (196721)
- Senno Verhoef (395219)
- Shahana Ahmed (146735)
- Shan Wang-Gohrke (89910)
- Siddhartha Kar (510873)
- Silje Nord (665045)
- Simon Cross (2273971)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Sofia Khan (79890)
- Soo Teo (3412994)
- Stephanie Peeters (3210717)
- Steve Ellis (395221)
- Steven Hart (395293)
- Stig Bojesen (3437723)
- Sue Healey (41187)
- Suleeporn Sangrajrang (89948)
- Susan Domchek (3405314)
- Susan Neuhausen (3405332)
- Susan Ramus (3405266)
- Susan Slager (547068)
- Sylvie Mazoyer (196744)
- Thilo DÄĆrk (3437810)
- Thomas BrÄĆșning (3437819)
- Thomas Hansen (183190)
- Tien Wong (3437762)
- Tjoung-Won Park-Simon (126466)
- Trinidad Caldes (3147195)
- Uffe Jensen (3437735)
- Ursula Eilber (102621)
- Ute Hamann (89879)
- Volker Arndt (146500)
- Wei Zheng (25452)
- William Blot (3074559)
- Xiao-Ou Shu (25450)
- Xingyi Guo (38056)
- Yael Laitman (196595)
- Ylva Paulsson-Karlsson (3147189)
- Yu-Tang Gao (25451)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
ćèćć: [èšèŒăȘă]ç§ć: = unknownæĄéć°: ăżă€ ă«ăȘă€ă€ćœç«ć
Źć (ăżă€ćœ ă«ăȘă€ă€ćœç«ć
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: è©ćșäžćŁœæŽççȘć·: JH051286ćœç«ç§ćŠćç©é€šæŽççȘć·: TNS-VS-94871
Mapping of the 17q21 locus.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- AgnĂšs Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- ElĆŒbieta ZĆowocka-PerĆowska (204566)
- Emma McCann (395229)
- Encarna B. GĂłmez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina AittomÀki (89889)
- Laima Tihomirova (196713)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p><i>Top 3 panels:</i> P-values of association (âlog<sub>10</sub> scale) with ovarian cancer risk for genotyped and imputed SNPs (1000 Genomes Project CEU), by chromosome position (b.37) at the 17q21 region, for <i>BRCA1</i>, <i>BRCA2</i> mutation carriers and combined. Results based on the kinship-adjusted score test statistic (1 d.f.). <i>Fourth panel:</i> Genes in the region spanning (43.4â44.9 Mb, b.37) and the location of the most significant genotyped SNPs (in red font) and imputed SNPs (in black font). <i>Bottom panel:</i> Pairwise r<sup>2</sup> values for genotyped SNPs on iCOG array in the 17q21 region covering positions (43.4â44.9 Mb, b.37).</p
Predicted breast and ovarian cancer absolute risks for <i>BRCA1</i> mutation carriers at the 5<sup>th</sup>, 10<sup>th</sup>, 90<sup>th</sup>, and 95<sup>th</sup> percentiles of the combined SNP profile distributions.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- AgnĂšs Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- ElĆŒbieta ZĆowocka-PerĆowska (204566)
- Emma McCann (395229)
- Encarna B. GĂłmez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina AittomÀki (89889)
- Laima Tihomirova (196713)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p>The minimum, maximum and average risks are also shown. Predicted cancer risks are based on the associations of known breast or ovarian cancer susceptibility loci (identified through GWAS) with cancer risk for <i>BRCA1</i> mutation carriers and loci identified through the present study. Breast cancer risks based on the associations with: 1q32, 10q25.3, 19p13, 6q25.1, 12p11, <i>TOX3</i>, 2q35, <i>LSP1</i>, <i>RAD51L1</i> (based on HR and minor allele frequency estimates from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t001" target="_blank">Table 1</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t002" target="_blank">Table 2</a>, and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212.s016" target="_blank">Table S4</a>) and <i>TERT </i><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212-Bojesen1" target="_blank">[31]</a>. Ovarian cancer risks based on the associations with: 9p22, 8q24, 3q25, 17q21, 19p13 (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t001" target="_blank">Table 1</a>) and 17q21.31, 4q32.3 (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t002" target="_blank">Table 2</a>). Only the top SNP from each region was chosen. Average breast and ovarian cancer risks were obtained from published data <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212-Antoniou10" target="_blank">[25]</a>. The methods for calculating the predicted risks have been described previously <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212-Antoniou11" target="_blank">[28]</a>.</p
Study design for selection of the SNPs and genotyping of <i>BRCA1</i> samples.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- AgnĂšs Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- ElĆŒbieta ZĆowocka-PerĆowska (204566)
- Emma McCann (395229)
- Encarna B. GĂłmez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina AittomÀki (89889)
- Laima Tihomirova (196713)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p>GWAS data from 2,727 <i>BRCA1</i> mutation carriers were analysed for associations with breast and ovarian cancer risk and 32,557 SNPs were selected for inclusion on the iCOGS array. A total of 11,705 <i>BRCA1</i> samples (after quality control (QC) checks) were genotyped on the 31,812 <i>BRCA1</i>-GWAS SNPs from the iCOGS array that passed QC. Of these samples, 2,387 had been genotyped at the SNP selection stage and are referred to as âstage 1â samples, whereas 9,318 samples were unique to the iCOGS study (âStage 2â samples). Next, 17 SNPs that exhibited the most significant associations with breast and ovarian cancer were selected for genotyping in a third stage involving an additional 2,646 <i>BRCA1</i> samples (after QC).</p
Associations with SNPs at the novel 17q21 region with ovarian cancer risk for <i>BRCA1</i> and <i>BRCA2</i> mutation carriers.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- AgnĂšs Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- ElĆŒbieta ZĆowocka-PerĆowska (204566)
- Emma McCann (395229)
- Encarna B. GĂłmez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina AittomÀki (89889)
- Laima Tihomirova (196713)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
*<p>HRs estimated under the single disease risk model.</p
Associations with breast or ovarian cancer risk for loci previously reported to be associated with cancer risk for <i>BRCA1</i> mutation carriers.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- AgnĂšs Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- ElĆŒbieta ZĆowocka-PerĆowska (204566)
- Emma McCann (395229)
- Encarna B. GĂłmez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina AittomÀki (89889)
- Laima Tihomirova (196713)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p>Freqâ=âfrequency of allele 2 in unaffected <i>BRCA1</i> carriers.</p><p>HRâ=âPer allele Hazard Ratio associated with allele 2, under a single disease risk model, unless specified.</p><p>r<sup>2</sup>: correlation between the SNP in the present study and the published SNP.</p>*<p>SNP not in <i>BRCA1</i> GWAS SNP allocation on iCOGS chip.</p>a<p>: rs13387042 was previously found to be associated only under the 2-df model.</p>b<p>: analysis under a competing risks model.</p
Analysis of associations with breast and ovarian cancer risk simultaneously (competing risks analysis) for SNPs found to be associated with breast or ovarian cancer.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- AgnĂšs Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- ElĆŒbieta ZĆowocka-PerĆowska (204566)
- Emma McCann (395229)
- Encarna B. GĂłmez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina AittomÀki (89889)
- Laima Tihomirova (196713)
- Lars JĂžnson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p>Analysis of associations with breast and ovarian cancer risk simultaneously (competing risks analysis) for SNPs found to be associated with breast or ovarian cancer.</p