Cost-effectiveness acceptability planes (two dimensional representation).

<p>Cost-effectiveness acceptability planes (two dimensional representation).</p

Expected net loss planes (two dimensional representation).

<p>Expected net loss planes (two dimensional representation).</p

Threshold regions over which each service model is preferred.

<p>Threshold regions over which each service model is preferred.</p

Technical efficiency frontier in cost-disutility space for PEACH and usual care.

<p>Technical efficiency frontier in cost-disutility space for PEACH and usual care.</p

Farrell’s production possibilities frontier for two inputs and one output (adapted from Coelli [41].

<p>Farrell’s production possibilities frontier for two inputs and one output (adapted from Coelli [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0115544#pone.0115544.ref041" target="_blank">41</a>].</p

Key eligibility criteria in the ketamine trial [24].

a<p>Leeds Assessment of Neuropathic Symptoms and Signs score (LANSS) <12;</p>b<p>LANSS score >12.</p

Scripted probes for the cognitive interview.

<p>Scripted probes for the cognitive interview.</p

Proportion of missing values for key variables in the ketamine sample data.

<p>AKPS  =  Australian-modified Karnofsky Performance Status; BPI  =  Brief Pain Inventory; EOLPRO  =  end of life patient reported outcome; MMSE  =  Mini-Mental State Examination; QOL  =  quality of life.</p

Summary of the correlations between EOLPRO scores and other established scales and clinical measures.

1<p>correlations were considered significant when the probability of making a type I error was less than 0.8% to allow for multiple testing;</p>*<p>statistically significant result; AKPS  =  Australian-modified Karnofsky Performance Status; BPI  =  Brief Pain Inventory; CI  =  bootstrap BCa confidence intervals.</p

Post-treatment EOLPRO scores and responder status cross tabulation.

<p>Post-treatment EOLPRO scores and responder status cross tabulation.</p