3 research outputs found
Efficient Synthesis of Fluorescent Coumarins and Phosphorous-Containing Coumarin-Type Heterocycles via Palladium Catalyzed Cross-Coupling Reactions
Quantum-chemical calculations on the spectral properties of some aryl substituted 3-
phosphonocoumarins were performed, and the effect of the substituents in the aryl moiety was
evaluated. The structures possessing promising fluorescent properties were successfully synthesized via Suzuki and Sonogashira cross-coupling. The synthetic protocol was also applied for the
phosphorous chemoisomer of 3-phosphonocoumarin, 1,2-benzoxaphosphorin, and their carboxylate
analogues. The optical properties of the arylated and alkynylated products were experimentally
determined. The obtained quantum-chemical and experimental results give the possibility for a
fine tuning of the optical properties of phosphorous-containing coumarin systems by altering the
substituent at its C-6 position