23 research outputs found

    Candida costochondritis associated with recent intravenous drug use

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    Candida osteoarticular infections are being reported with increasing frequency, possibly due to an expanding population at risk. However, Candida costochondritis is uncommon. We report two cases of Candida costochondritis in patients who presented with subacute-onset chest wall swelling and whose only identifiable risk factor was a history of recent intravenous drug use

    Candida costochondritis associated with recent intravenous drug use

    Get PDF
    Candida osteoarticular infections are being reported with increasing frequency, possibly due to an expanding population at risk. However, Candida costochondritis is uncommon. We report two cases of Candida costochondritis in patients who presented with subacute-onset chest wall swelling and whose only identifiable risk factor was a history of recent intravenous drug use

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Registered Ship Notes

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    https://digitalmaine.com/blue_hill_documents/1179/thumbnail.jp

    ‘It’s in the game’: sport fans, film and digital gaming

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    This essay compares the relative successes of sport-related films and sport-related digital games. Where sport-related films are relatively infrequent and even rarer successful when compared with other genres of film, sport-related games are a massively popular and successful genre of digital gaming. In order to understand this discrepancy, and in particular sport fan’s relationship with both film and games, this essays draws on the concept of ‘narrative’ and specifically Ricoeur’s ‘narrative identity’. In particular, this essay suggests that sport teams/clubs are to some degree polysemic texts, which allow supporters to construct their own individual narratives around these. However, it is suggested that sport-related films, which tend to offer only limited narratives, are unlikely to fit with fans’ own narrative identities, whereas digital games, with their more fluid narratives, are more easily located within fans’ relationships and narratives with the teams/clubs they support
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