450 research outputs found

    Paying it forward

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    Low vitamin D status is associated with impaired bone quality and increased risk of fracture-related hospitalization in older Australian women

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    The vitamin D debate relates in part to ideal public health population levels of circulating 25-hydroxyvitamin D (25OHD) to maintain bone structure and reduce fracture. In a secondary analysis of 1,348 women aged 70-85 years at baseline (1998) from the Perth Longitudinal Study of Aging in Women (PLSAW, a five-year calcium supplementation trial followed by two five-year extensions), we examined the dose-response relations of baseline plasma 25OHD with hip DXA BMD at year 1, lumbar spine BMD and trabecular bone score (TBS) at year 5, and fracture-related hospitalizations over 14.5 years obtained by health record linkage. Mean baseline plasma 25OHD was 66.9±28.2 nmol/L and 28.5%, 36.4% and 35.1% of women had levels50 nmol/L are a minimum public health target and 25OHD levels beyond 75 nmol/L may not have additional benefit to reduce fracture risk

    Taxation through time: an intertemporal assessment of the taxation of human capital in Atlantic Canada

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    We examine the (dis)incentive effects created by the respective tax systems to invest in human capital in Atlantic Canada and compare this to a select group of provinces from the rest of Canada. While findings show a steady decline in effective tax rates through the years, thereby creating an incentive effect to invest in post-secondary education, disproportionately higher rate gap differentials in the Atlantic Provinces, on average, combined with negative comparative statics reveal a somewhat different undertone. The counterproductive nature of the competing policies effectively nullifies any status quo argument for education or tax policy in the Atlantic Provinces, when compared to their brethren. The graduate retention rebate provides some solace to the narrative in helping to alleviate early tax burdens and equalize returns, but is difficult to claim effectiveness in assuaging any monetary windfall associated with migration

    In Situ Surface Voltage Measurements of Dielectrics Under Electron Beam Irradiation

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    New instrumentation has been developed for non- contact, in vacuo measurements of the electron beam-induced surface voltage as a function of time and position for non- conductive spacecraft materials in a simulated space environment. The novel compact system uses two movable capacitive sensor electrodes to measure surface charge distributions on samples, using a non-contact method that has little effect on charge dissipation from sample. Design details, calibration and characterization measurements of the system are presented, with \u3c1 V to \u3e30 kV surface voltage range, \u3c0.5 V voltage resolution, and \u3c1.5 mm spatial resolution. Used in conjunction with the capabilities of an existing ultrahigh vacuum electron emission test chamber, the new instrumentation facilitates measurements of charge accumulation, bulk resistivity, effects of charge depletion and accumulation on yield measurements, electron induced electrostatic breakdown potentials, radiation induced conductivity effects, and the radial dispersion of surface voltage. Three types of measurements of surface voltage for polyimide (Kapton HNTM) serve to illustrate the research capabilities of the new system: (i) accumulation using a pulsed electron beam, while periodically measuring the surface voltage; (ii) post charging, as deposited charge dissipated to a grounded substrate; and (iii). the evolution of spatial profile resulting from an incident Gaussian beam. Theoretical models for sample charging and discharge are outlined to predict the time, temperature, and electric field dependence of the sample’s net surface voltage

    In Situ Surface Voltage Measurements of Dielectrics Under Electron Beam Irradiation

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    New instrumentation has been developed for non-contact, in vacuo measurements of the electron beam-induced surface voltage as a function of time and position for non-conductive spacecraft materials in a simulated space environment. Used in conjunction with the capabilities of an existing ultrahigh vacuum electron emission analysis chamber, the new instrumentation facilitates measurements of charge accumulation, bulk resistivity, effects of charge depletion and accumulation on yield measurements, electron induced electrostatic breakdown potentials, radiation induced conductivity effects, and the radial dispersion of surface voltage. The novel system uses two movable capacitive sensor electrodes that can be swept across the sample to measure surface charge distributions on samples, using a non-contact method that does not dissipate sample charge. Design details, calibration and characterization measurements of the system are presented, for a surface voltage range from30 kV, voltage resolution \u3c1 \u3eV, and spatial resolutio

    Risk and charitable organizations: the case of Atlantic Canada

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    Using panel data from 2003-2010 on charitable organizations in Canada we explore the implications that exposure to risk, in various guises, has on organizations' ability to meet their mandate. We run a random effects panel estimation focusing our attention on the case of Atlantic Canada in an effort to explore the idiosyncrasies that make it an interesting case study, and a microcosm of sorts for producing risk metrics in general. A comparative analysis is provided with the Canadian charitable sector as a whole to contrast the results and afford a context for discussion. Results suggest that diversification in revenue streams may in fact increase risk for charitable firms; and comprehensive modeling techniques, which categorize the entire Canadian market quite well, lead to increased noise in estimating exposure to risk for Atlantic Canada firms. The latter seem somewhat more sensitive to exogenous economic changes, when compared to the entire marketplace

    An Ontology-Based Collaborative Interorganizational Knowledge Management Network

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    Web contents can be represented in a structural form by a finite list of vocabularies and their relationships using ontologies. The concept of ontology and its related mediation methods is capable of enhancing the collaboration among Knowledge Management (KM) approaches that only focus on managing organizational knowledge. Those KM approaches are developed in accordance with organizational KM strategies and business requirements without the concern of system interoperation. In this research, an ontology-based collaborative inter-organizational KM network is proposed to provide a platform for organizations to access and retrieve inter-organizational knowledge in a similar domain

    Keeping the Promise of Community-Based Participatory Research: Integrating Applied Critical Rhetorical Methods to Amplify the Community’s Voice for Trial Development

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    Community-based participatory research (CBPR) represents an important improvement in the integration of marginalized voices into research programs by including community members in the designs, conduct, and dissemination of studies. CBPR often features a social justice component, generating studies designed to reduce societal disparities and improve outcomes for disenfranchised groups. However, the practical implementation of CBPR usually fails to capitalize on this promise, using the same traditional research methodologies, leadership structures, trial designs, and research questions that inculcate researcher bias. In response to the problem, we propose a new solution: Applied critical rhetorical research (ACRR) integrated into the CBPR approach to clinical health research. ACRR research combines critical/cultural studies and rhetorical methods to amplify the figurative voice of marginalized populations. ACRR can expose how majority power (i.e., hegemony) manifests in social institutions like healthcare and government, where its meanings and subjectivities are absorbed. ACRR analyses enhance CBPR by shaping research in directions that reduce stigma, unintended disenfranchisement, and culturally bound bias, increasing the yield from CBPR for researchers and the community
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