203 research outputs found

    Analisis Faktor-faktor Yang Mempengaruhi Status Perusahaan Pasca Ipo Dengan Analisis Multinomial Logit

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    This research has a purpose to provide empirical evident about factors that affect firms status after IPO. The examined factors on this research are firm characteristics including financial ratio, industry structure, firm's sensitivity to macroeconomic variables, underwriter reputation and ownership structure.The samples consist of 84 firms which had positive net income, positive equity book value and still listed until 2002; 24 firms which had negative net income from 2000 through 2001 and still listed; 48 firms which had negative net income and negative equity book value from 2000 through 2001 and still listed; and 19 firms which delisted from 1999 through 2002. Moreover, it is chosen by purposive sampling. The statistic method used to test on the research hypothesis is multinomial logit regression. Indirect method and direct method technique is used to gain a model that has the highest classification power in determination firms status after IPO.The result show that direct method had a higher classification power rather than indirect method. This research also indicate that firm characteristic include financial ratio, industry structure, firm's sensitivity to macroeconomic variables, and underwriter reputation is a significant variables in determination firms status after IP

    Differential regulation of cell proliferation and protease secretion by epidermal growth factor and amphiregulin in tumoral versus normal breast epithelial cells

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    Amphiregulin (AR) is a heparin-binding epidermal growth factor (EGF)-related peptide that seems to play an important role in mammary epithelial cell growth regulation. We have investigated the regulation of AR-gene expression and -protein secretion by EGF in normal breast epithelial cells (HMECs), as well as in the tumoral breast epithelial cell lines MCF-7 and MDA-MB231. EGF induced a dose-dependent increase of AR mRNA level in both normal and tumoral cells. Thus, 10−8M EGF stimulated AR expression in HMECs to 140–300% of control. A similar EGF concentration increased AR mRNA level to 550% and 980% of control in MCF-7 and MDA-MB231 cells, respectively. This was accompanied by an accumulation of AR into conditioned culture media. However, HMECs secreted in response to EGF, 5–10 fold more AR than tumour cells. Furthermore, the potential participation of AR in the regulation of the plasminogen activator (PA)/plasmin system was investigated. Whereas HMEC-proliferation was stimulated by AR, the levels of secreted urokinase-type plasminogen activator (uPA) and type-1 plasminogen activator inhibitor (PAi-1) remained unaffected. Conversely, AR failed to regulate the proliferation of tumoral cell lines but induced an accumulation of uPA and PAi-1 into culture media. This was accompanied by an increase of the number of tumoral cells that invaded matrigel in vitro. Moreover, the presence of a neutralizing anti-uPA receptor antibody reversed the increased invasiveness of MDA-MB231 cells induced by AR. These data reveal differential behaviour of normal versus tumoral breast epithelial cells in regard to the action of AR and demonstrate that, in a number of cases, AR might play a significant role in tumour progression through the regulation of the PA/plasmin system. © 2001 Cancer Research Campaign http://www.bjcancer.co

    Impact of Inclement Weather on Overwinter Mortality of Montezuma Quail in Southeast Arizona

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    Inclement weather such as droughts or hard freezes are known to negatively impact quail species and population viability models exist which have evaluated northern bobwhite (Colinus virginianus) response to summer and winter catastrophes. Previous research suggests inclement weather may be an important factor that contributes to mortality of Montezuma quail (Cyrtonyx montezumae), but few data have been collected to evaluate actual rates of overwinter mortality. We evaluated the overwinter mortality of Montezuma quail in southeast Arizona following an episode of severe winter weather consisting of 27.54 cm of precipitation, which occurred from January to March 2010. Overwinter mortality for radio-marked birds (n 1⁄4 23) was 95.6%. Total abundance using flush counts at a control site estimated an 88% reduction in the population following the episode of above-average precipitation. Post-hunting season flush counts across multiple study sites throughout the Coronado National Forest also support this trend. The 3-year (2007–2009) average (6 SD) (41.67 6 4.73) of birds flushed was ~ 80% higher than number of birds (n 1⁄4 8) flushed in the 2010 post-hunting season

    Use of Portable Infrared Cameras to Facilitate Detection and Capture Success of Montezuma Quail

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    Survey and trapping methods for Montezuma quail (Cyrtonyx montezumae) require means not traditionally used for other quail species (e.g., northern bobwhite, Colinus virginianus). Trapping Montezuma quail is most effective using pointing dogs at night when coveys can be located and captured by net during roosting. However, reduced visibility at night, cryptic coloration of plumage, and behavioral adaptive stillness reduce detection rates and increase accidental flushing of birds while searching for roost locations. Forward-looking infrared (FLIR) cameras have been used to aid in detection of cryptic wildlife, including avifauna roosting sites. We conducted 25 survey and night-trapping sessions for Montezuma quail in southeast Arizona using a combination of trained pointing dogs and a portable FLIR camera. Detection of coveys on a roost was less successful when ambient climate conditions were freezing (below 3.88 8C), when residual heat signatures from surrounding soils and rocks were greater than 18.33 8C, or when density of grass cover exceeded 40% and the distance to covey was . 2.5 m. The small thermal signatures of quail were often obstructed by vegetative cover or confused with residual thermal signatures reflected by inanimate objects (e.g., rocks, bare ground). Successful detection of coveys combining the use of dogs and FLIR before trapping was 6.06%. Trapping success and detection of coveys with FLIR was improved when used with radiotelemetry and coveys which included radio-marked individuals. Proper tuning of FLIR camera sensitivity to a limited thermal bandwidth, or isotherm range, may effectively narrow covey locations approximated by a pointing dog. The FLIR camera was of limited benefit when actively trapping coveys with dogs and a team of 2–3 people, but may be beneficial for non-invasive monitoring and estimating covey size of marked birds on roosts in landscapes with reduced vegetative cover

    Increased age and male sex are independently associated with higher frequency of blood–cerebrospinal fluid barrier dysfunction using the albumin quotient

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    Background: The cerebrospinal fluid (CSF)/serum quotient of albumin (QAlb) is the most used biomarker for the evaluation of blood–cerebrospinal fluid barrier (B-CSF-B) permeability. For years QAlb was considered only as an age-related parameter but recently it has also been associated to sex. The aim of the present study was to explore the impact of sex in the determination of B-CSF-B dysfunction. Methods: The analysis was retrospectively conducted on subjects consecutively admitted to the neurological ward. CSF and serum albumin levels were measured by immunonephelometry and pathological QAlb thresholds were considered: 6.5 under 40 years, 8.0 in the age 40–60 and 9.0 over 60 years. Results: 1209 subjects were included in the study. 718 females and 491 males (age: 15–88 years): 24.6% of patients had a diagnosis of multiple sclerosis, 23.2% suffered from other inflammatory neurological diseases, 24.6% were affected by non-inflammatory neurological diseases, and for 27.6% of patients the final neurological diagnosis could not be traced. Dysfunctional B-CSF-B was detected more frequently (44 vs. 20.1%, p < 0.0001) and median QAlb value were higher (7.18 vs. 4.87, p < 0.0001) in males than in females in the overall study population and in all disease sub- groups. QAlb and age were positively correlated both in female (p < 0.0001) and male (p < 0.0001) patients, however the slopes of the two regression lines were not significantly different (p = 0.7149), while the difference between the elevations was extremely significant (p < 0.0001) with a gap of 2.2 units between the two sexes. Finally, in a multivari- able linear regression analysis increased age and male sex were independently associated with higher QAlb in the overall study population (both p < 0.001) and after stratification by age and disease group. Conclusions: Accordingly, identification and validation of sex-targeted QAlb thresholds should be considered as a novel tool in an effort to achieve more precision in the medical approach

    Post-Fire Succession and Montezuma Quail in a Semi-Desert Grassland of Southeast Arizona

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    A 1,011.7-ha wildfire occurred in southeast Arizona in May 2009 and provided an opportunity to evaluate pre- and post-fire abundance of and habitat use by Montezuma quail (Cyrtonyx montezumae) through use of flush surveys and radiotelemetry. We evaluated movements of radio-marked quail from 2 months prior to the burn to 12 months post-burn. We observed strong site fidelity with coveys persisting in small patches of unburned areas and micro-topography, despite extensive reduction in cover in the surrounding landscape. We documented 46.7% reduction in abundance using flush counts within the first 2 weeks post-fire, and 66.7% reduction within 3 weeks post-fire. We also documented roosting within a fire-affected area and successful nesting by Montezuma quail a few months following a wildfire

    Ranges and Movements of Montezuma Quail in Southeast Arizona

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    Historical assumptions about Montezuma quail movements and home ranges at the population level are limited due to the lack of markrecapture studies on this species from which solid conclusions can be derived. Such information is crucial for estimating population sizes, densities, and rate of emigration and immigration throughout the landscape. Our study examined home range size of 29 Montezuma quail and movements of 65 quail in southeast Arizona from 2008–2010. We used radio telemetry to follow radio-tagged birds in 3 study sites that varied in vegetation composition and topography. Mean home range size (MCP) was about was similar (51 ha) to the largest use area (50 ha) described in the literature for this species. The largest MCP home range estimate (206.7 ha) was far larger than what has been reported in the literature. Within a season, the largest mean maximum distance moved between 2 locations was 1,128.4 ± 619.5 m and the largest maximum linear distance between 2 locations for an individual was 2,375.5 m. Results from our research should help to address knowledge gaps about Montezuma quail home ranges and movements and provide a baseline to assist management of this species in the future

    Survival Demographics of Montezuma Quail in Southeast Arizona

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    Many facets of Montezuma quail (Cyrtonyx montezumae mearnsi) population dynamics, such as survival and causes of mortality, are unknown because of limited or lack of mark–recapture studies on wild populations of this species. Much of what is known about this species comes from casual observations in the field or from dog-assisted flush-count surveys. Further insight into rate and causes of mortality for this species is necessary to ensure proper conservation measures. We evaluated survival and causes of mortality of Montezuma quail in southeastern Arizona from winter 2007 to spring 2010. Survival was determined from quail captured, radiotagged, and monitored among 3 separate study sites. In 2 of these sites hunting was permitted; and in 1 site (the control) hunting was not permitted. Estimation of accurate mortality rates in hunted sites was complicated by large quantities of censored data, some of which was attributable to lack of reported mortalities from hunting. Mortality in the control site may have been compounded by a combination of stochastic events (i.e., wildfire, freezing) occurring during the study. Mortality rate for all sites were higher than any estimates reported or hypothesized in known scientific literature. The estimated rate of survival, combined among the 3 sites, was 21.9% from autumn 2008 to autumn 2009

    Factors Influencing the Movement of Livestock Guardian Dogs in the Edwards Plateau of Texas: Implications for Efficacy, Behavior, and Territoriality

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    Livestock guardian dog (Canis lupus familiaris; LGD) breeds of domestic dog worldwide provide a degree of control over predation losses. The application of LGDs as a wildlife damage management tool evolved as a cultural practice in the Old World. In the 1970s, this tool emerged in North America. Despite several decades of science and application, gaps still exist in our knowledge regarding applications for LGDs. From February 2016 to November 2017, we deployed global positioning system transmitters on 4 LGDs on a 20-km2 ranch in Menard County, Texas, USA operated by Texas A&M AgriLife Research to investigate their fine scale movement and activity patterns, site fidelity to livestock management units (i.e., pastures), and fidelity to anthropogenic features, such as feed and water locations. The LGDs remained within study site boundaries for 90% of the study period. Additionally, daily activity patterns differed for dogs associated primarily with sheep (Ovis aries) and goats (Capra aegagrus hircus). All of the LGDs we studied were active throughout the 24-hour day. We determined that feed and water locations concentrated LGD activity to an extent, likely reflecting a livestock affinity for water sources, and provide an additional method by which to distribute them over the landscape. Our results, based on a small sample size, suggest that LGDs may provide effective association with livestock management areas, maintain a high fidelity to area perimeter boundaries, and distribute themselves across the area of use

    Hunter Motivations and Use of Wild Pigs in Texas, USA

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    Wild pigs (Sus scrofa) are a widespread exotic, invasive species that pose ecological, agricultural, and human health risks in their invaded range. Wildlife managers must manage wild pig abundance and range expansion to mitigate these risks. The diversity of stakeholders involved in the issue of wild pig management complicates efforts to manage the species, and, to be successful, wildlife professionals must consider the human dimensions associated with wild pig management. The prevalence of privately owned lands in Texas, USA necessitates cooperation to enact effective management policies. In this study, we investigate the impact of hunter motivations on wild pig harvest quantity. Motivations driving wild pig hunting are diverse. While the majority of wild pig hunters in Texas are motivated by trophy value, meat-motivated hunters harvest more wild pigs per day afield. Wildlife managers should develop plans that include various management techniques to control wild pig population growth and damage. Education and outreach will continue to be important for involving private landowners in effective wild pig management
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