Polymorphisms of genes related to testosterone metabolism analyzed in this study.

<p>Polymorphisms of genes related to testosterone metabolism analyzed in this study.</p

Genotype frequencies.

<p>Genotype frequencies (%) of the analyzed single nucleotide polymorphisms in intellectually gifted (black boxes) and control (white boxes) boys. Genotypes of the polymorphisms are shown below the graphs.</p

Androgen receptor gene.

<p>Number of CAG repeats in the first exon of the androgen receptor gene in intellectually gifted (black boxes) and control (white boxes) boys (data are presented as mean+standard deviation).</p

Allele frequencies.

<p>Allele frequencies of the single nucleotide polymorphisms that were significantly different distributed in intellectually gifted (black boxes) and control (white boxes) boys. Genotypes of the polymorphisms are shown below the graphs.</p

15 SNPs chosen for individual genotyping with the P-values from the pooling stage.

a<p>Indicates SNPs that did not survive quality control measures to be included in the association validation analysis.</p

Pearson's correlation of real allele frequencies in total sample (calculated from individual genotyping,y-axis) and frequency estimates from pooled DNA (mean RAS-scores of the 15 pools, x-axis) of 32 SNPs (r = 0.8424).

<p>Pearson's correlation of real allele frequencies in total sample (calculated from individual genotyping,y-axis) and frequency estimates from pooled DNA (mean RAS-scores of the 15 pools, x-axis) of 32 SNPs (r  =  0.8424).</p

Quantile-quantile plot of the SNPs tested in the pooled DNA association stage.

<p>Quantile-quantile plot of the SNPs tested in the pooled DNA association stage.</p

Manhattan plot of the SNPs tested in the pooled DNA association stage.

<p>Manhattan plot of the SNPs tested in the pooled DNA association stage.</p

Graphical summary of association results from the genome-wide screen of pooled samples.

<p>X-axis represents the chromosome position; y-axis shows -log10 of the P-value obtained for each SNP.</p

Association results of SNPs associated at a significance value of 0.05 or less in the individual genotyping stage, along with their pooling stage results.

<p>SNPs written in bold are significant after correcting for multiple testing.</p