134 research outputs found
The Future of Cryptocurrency and Real Estate Transactions
Bitcoin and other cryptocurrencies are all the rage right now and are beginning to make their ways into everyday transactions— including real estate transactions. This article discusses whether using cryptocurrencies to complete real estate transactions will become the norm in the near future. Cryptocurrency laws in general are few and far between, but laws surrounding cryptocurrency and real property are even more sparse. Recent case law involving cryptocurrency is a major focus of this article, along with background knowledge about cryptocurrency and the meaning of “money” as we know it today. The article concludes with a discussion about the unlikelihood of real estate transactions being conducted through the use of cryptocurrencies when few are willing to put full trust in their long-term acceptance
Viral-immune cell interactions at the maternal-fetal interface in human pregnancy
The human decidua and placenta form a distinct environment distinguished for its promotion of immunotolerance to infiltrating semiallogeneic trophoblast cells to enable successful pregnancy. The maternal-fetal interface also successfully precludes transmission of most pathogens. This barrier function occurs in conjunction with a diverse influx of decidual immune cells including natural killer cells, macrophages and T cells. However, several viruses, among other microorganisms, manage to escape destruction by the host adaptive and innate immune system, leading to congenital infection and adverse pregnancy outcomes. In this review, we describe mechanisms of pathogenicity of two such viral pathogens, Human cytomegalovirus (HCMV) and Zika virus (ZIKV) at the maternal-fetal interface. Host decidual immune cell responses to these specific pathogens will be considered, along with their interactions with other cell types and the ways in which these immune cells may both facilitate and limit infection at different stages of pregnancy. Neither HCMV nor ZIKV naturally infect commonly used animal models [e.g., mice] which makes it challenging to understand disease pathogenesis. Here, we will highlight new approaches using placenta-on-a-chip and organoids models that are providing functional and physiologically relevant ways to study viral-host interaction at the maternal-fetal interface
CMBPol Mission Concept Study: Probing Inflation with CMB Polarization
We summarize the utility of precise cosmic microwave background (CMB)
polarization measurements as probes of the physics of inflation. We focus on
the prospects for using CMB measurements to differentiate various inflationary
mechanisms. In particular, a detection of primordial B-mode polarization would
demonstrate that inflation occurred at a very high energy scale, and that the
inflaton traversed a super-Planckian distance in field space. We explain how
such a detection or constraint would illuminate aspects of physics at the
Planck scale. Moreover, CMB measurements can constrain the scale-dependence and
non-Gaussianity of the primordial fluctuations and limit the possibility of a
significant isocurvature contribution. Each such limit provides crucial
information on the underlying inflationary dynamics. Finally, we quantify these
considerations by presenting forecasts for the sensitivities of a future
satellite experiment to the inflationary parameters.Comment: 107 pages, 14 figures, 17 tables; Inflation Working Group
contribution to the CMBPol Mission Concept Study; v2: typos fixed and
references adde
Comparing Brane Inflation to WMAP
We compare the simplest realistic brane inflationary model to recent
cosmological data, including WMAP 3-year cosmic microwave background (CMB)
results, Sloan Digital Sky Survey luminous red galaxies (SDSS LRG) power
spectrum data and Supernovae Legacy Survey (SNLS) Type 1a supernovae distance
measures. Here, the inflaton is simply the position of a -brane which is
moving towards a -brane sitting at the bottom of a throat (a warped,
deformed conifold) in the flux compactified bulk in Type IIB string theory. The
analysis includes both the usual slow-roll scenario and the Dirac-Born-Infeld
scenario of slow but relativistic rolling. Requiring that the throat is inside
the bulk greatly restricts the allowed parameter space. We discuss possible
scenarios in which large tensor mode and/or non-Gaussianity may emerge. Here,
the properties of a large tensor mode deviate from that in the usual slow-roll
scenario, providing a possible stringy signature. Overall, within the brane
inflationary scenario, the cosmological data is providing information about the
properties of the compactification of the extra dimensions.Comment: 45 pages 11 figure
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