4 research outputs found
Antigenic and genomic characterization of adenovirus associated to respiratory infections in children living in Northeast Brazil
From January to December 1998, nasopharyngeal aspirates were obtained
from 482 children with acute respiratory infections attended in
emergence department and wards of a teaching hospital in the city of
Salvador, Brazil. The samples were tested for the presence of
adenovirus by isolation in tissue culture and indirect
immunofluorescence assay. Eleven adenoviruses were detected by both
methods in the same clinical samples. Infections by adenovirus were
observed during seven months of the year without association with rainy
season. Genome analysis was performed on these 11 isolates. Species C
was represented by serotypes 1, 2 and 5. Within species B, only
serotype 7 (Ad7) was detected. Two genomic variants of Ad1, two
variants of Ad2, one of Ad5, and one of Ad7 (7h) were identified. This
is the first study of molecular epidemiology of adenovirus associated
to acute respiratory infections in children living in Northeast Brazil,
and contributes to a better understanding of adenovirus infections in
the country
ENTEROVIRUSES ISOLATED FROM PATIENTS WITH ACUTE RESPIRATORY INFECTIONS DURING SEVEN YEARS IN RIO DE JANEIRO (1985-1991)
Enteroviruses were investigated in respiratory secretions collected from patients with acute respiratory infections (ARI) over a seven year period (1985-1991), as part of a longitudinal study of ARI aetiology. All the viruses that are most commonly associated with ARI were found in this study. Among the virus isolates, enteroviruses were only less frequent than respiratory syncytial viruses, adenoviruses and influenzaviruses. Forty five enterovirus samples were isolated from patients with either upper respiratory tract infections (URTI) or lower respiratory tract infections (LRTI). From these enterovirus isolates, thirty one samples were identified as poliovirus (n=18) and non polio enterovirus (n=13) by serum neutralization. Poliovirus were identified as type 1 and 2 and all of them were vaccinal strains. From thirteen non polio enterovirus, twelve were identified as echovirus serotypes 1, 2, 7, 11, 19 and 31. The remainder was identified as coxsackievirus B4