Intervención cognitiva conductual de un caso de depresión en un joven de 25 años

The main objective of the present clinical study was to present the effectiveness of a Cognitive-Behavioral Treatment Program in the case of Depression, which presented comorbidity with anxiety. The person evaluated was a 23-year-old man with higher education in the process of obtaining his professional title, who currently lives with his parents. The patient was evaluated through the clinical interview and psychometric instruments which allowed confirming the clinical diagnosis. The instruments used were the cognitive-behavioral medical history, Beck's Depression Inventory, Beck's Anxiety Inventory, Millon's multifaceted Personality Inventory, Ellis's Irrational Ideas Questionnaire, Rosenberg's Self-Esteem Questionnaire, and Self-Records. The design of the cognitive-behavioral program was organized according to the objectives outlined after the evaluation, with 24 sessions, structured in psychoeducation and training through different techniques per session. According to the results, the increase in healthy behavior, decrease in depressive symptoms, reduction of indicators of anxiety, depression and irrational ideas in the patient can be disclosed. Therefore, it can be concluded that the cognitive-behavioral program intervention was efficient in its development

Efectividad de un programa breve para la reducción de estrés en personal de salud durante el contexto de la pandemia COVID-19: Un estudio piloto

Objective: To determine the influence of a brief stress reduction program in health workers of the National Maternal and Perinatal Institute during the COVID-19 pandemic. Materials and Methods: This research corresponds to a quasi-experimental study, which consist of the elaboration and application of a brief stress reduction program in workers of the Puericulture area of the INMP. The population consisted of 45 workers, 30 of whom complied with the inclusion criteria for the pilot study, from which a sample of 15 participants was distributed, by convenience, for the experimental group and 15 for the control group. The Depression, Anxiety and Stress Scale (Dass21) was applied at the beginning of the investigation and after concluding the program. The analysis of frequencies and percentages of the variable, analysis of adjusted goodness of fit to the normal curve, and Student's t-tests for correlated samples (p<0.05) pre and post intragroup test with a confidence level of 95% were carried out. Results: Significant differences were found in the experimental group in their pre and post treatment measures respectively in the variables Stress (T=5.20, p<0.001, D=0.742, Mean Dif=3.00); Anxiety (T=3.15, p<0.007, D=0.414, Mean Dif=2.20) and Depression (T=3.97, p<0.001, D=0.426, Mean Dif=3.97) reducing the averages of these variables after the application of the pilot program. Conclusion: The brief program for stress reduction is effective for stress reduction, and due to the fact that in its sessions cognitive behavioral strategies for the improvement of mental health were trained, indicators of anxiety and depression present in the sample were reduced in a secondary way.Objetivo. Determinar la influencia de un programa breve de reducción del estrés en trabajadores de salud del Instituto Nacional Materno perinatal durante la pandemia COVID-19. Materiales y Métodos. Esta investigación corresponde a un estudio cuasi experimental, que consiste en la elaboración y aplicación de un programa breve de reducción del estrés en trabajadores del área de Puericultura del INMP. La población estuvo conformada por 45 trabajadores, 30 de ellas cumplieron con los criterios de inclusión para el estudio piloto, de las cuales se distribuyó, por conveniencia, una muestra de 15 participantes para el grupo experimental y 15 para el grupo control. Se aplicó la Escala de Depresión, ansiedad y estrés (Dass21) al inicio de la investigación y luego de concluir con el programa. Se realizó el análisis de frecuencias y porcentajes de la variable, análisis de ajuste de bondad a la curva normal, y pruebas T Student para muestras relacionadas (p<0.05) pre y post test intragrupo con un nivel de confianza al 95%. Resultados.  Se encontró diferencias significativas en el grupo experimental en sus medidas pre y post tratamiento respectivamente en las variables Estrés (T=5.20, p<0.001, D=0.742, Dif medias=3.00); Ansiedad (T=3.15, p<0.007, D=0.414, Dif medias=2.20) y Depresión (T=3.97, p<0.001, D=0.426, Dif medias=3.97) reduciéndose las medias de dichas variables post aplicación del programa piloto. Conclusión. El programa breve para la reducción del estrés es efectivo para la reducción del estrés, a su vez debido a que en sus sesiones se entrenaron estrategias cognitivas conductuales para la mejora de la salud mental, se redujo, de forma secundaria, indicadores de ansiedad y depresión presentes en la muestra

ARIA 2016 : Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA-disseminated and implemented in over 70 countries globally-is now focusing on the implementation of emerging technologies for individualized and predictive medicine. MASK [MACVIA (Contre les Maladies Chroniques pour un Vieillissement Actif)-ARIA Sentinel NetworK] uses mobile technology to develop care pathways for the management of rhinitis and asthma by a multi-disciplinary group and by patients themselves. An app (Android and iOS) is available in 20 countries and 15 languages. It uses a visual analogue scale to assess symptom control and work productivity as well as a clinical decision support system. It is associated with an inter-operable tablet for physicians and other health care professionals. The scaling up strategy uses the recommendations of the European Innovation Partnership on Active and Healthy Ageing. The aim of the novel ARIA approach is to provide an active and healthy life to rhinitis sufferers, whatever their age, sex or socio-economic status, in order to reduce health and social inequalities incurred by the disease.Peer reviewe

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

An embedding technique to determine ττ backgrounds in proton-proton collision data

An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe

Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

Peer reviewe

Measurement of the azimuthal anisotropy of Y(1S) and Y(2S) mesons in PbPb collisions at root s(NN)=5.02 TeV

The second-order Fourier coefficients (v(2)) characterizing the azimuthal distributions of Y(1S) and Y(2S) mesons produced in PbPb collisions at root s(NN) = 5.02 TeV are studied. The Y mesons are reconstructed in their dimuon decay channel, as measured by the CMS detector. The collected data set corresponds to an integrated luminosity of 1.7 nb(-1). The scalar product method is used to extract the v2 coefficients of the azimuthal distributions. Results are reported for the rapidity range vertical bar y vertical bar < 2.4, in the transverse momentum interval 0 < pT < 50 GeV/c, and in three centrality ranges of 10-30%, 30-50% and 50-90%. In contrast to the J/psi mesons, the measured v(2) values for the Y mesons are found to be consistent with zero. (C) 2021 The Author(s). Published by Elsevier B.V.Peer reviewe

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| &lt; 0.03 at 95% confidence level. [Figure not available: see fulltext.

Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe