Cervical epithelial changes in a tertiary hospital in northern Nigeria

Introduction: Cervical cancer is the commonest gynaecological malignancy in Nigeria, accounting for most deaths from cancers in women. Screening remains one of the best ways to prevent this catastrophe.Methodology: This was a cross sectional study conducted among patients that presented for cervical cancer screening at the Jos University Teaching Hospital, Jos, Plateau State, North Central Nigeria over a Five-year period (1st August, 2006-31st July, 2011). Data was analyzed for frequencies using EPI Info 3.5.1, CDC, Atlanta, USA.Results: During the period of study (74.5%) of the 7863 women screened were normal. Inflammatory changes, LSIL and HSIL, were the commonest abnormalities. Eight point four percent (8.4.%) were either ASC-US or ASC-H, 35 (0.4%) were AGUS or AGUS-N. LSIL and HSIL were 547 (7.0%) and 193 (2.4%) respectively. One thousand, six hundred and seventy two (21.2%) were inflammation changes, bacterial infection, or trichomoniasis. Thirty two (0.4%) cases of suspected invasive carcinoma were seen.Conclusion: The abnormal cytological abnormality rate was high. More effort needs to be put in place to ensure that women have access to screening to reduce the burden of cervical cancer in this environment.Keywords: Paps smear, intraepithelial changes, cervical cancer, Jos University Teaching HospitalTrop J Obstet Gynaecol, 30 (1), April 201

Clinicopathological Profile of Malignant Tumors of the Oropharynx at the Jos University Teaching Hospital, Jos, Nigeria

Background: Due to recent lifestyle changes, the worldwide incidence of malignant oropharyngeal tumors is on the increase. This study focuses on the clinical and pathological profile of malignant tumors of the oropharynx as seen in a north-central Nigerian teaching hospital.Methodology: This is a descriptive retrospective analysis of the clinical and pathological profile of this disease.Results: Six patients aged between 37 years and 78 years had malignant oropharyngeal tumors. There were 5 (83.3%) males and 1 (16.7%) female. All patients presented with cervical swelling, dysphagia, odynophagia and muffled voice with dental caries, oral and oropharyngeal swelling. Four (66.7%) patients presented with dyspnea and 3 (50%) with otalgia and deafness. Three (50%) patients had histologic diagnosis of non-Hodgkin's lymphoma(centroblastic), 1 (16.7%) had lymphoepithelioma and 2 ( 33.3%) had squamous cell carcinoma. Two (33.3%) patients died during treatment, 3 (50%) defaulted and 1 (16.7%) has been followed up for 5 years and is tumor free.Conclusion: Oropharyngeal cancer has a poor prognosis in the tropics due to late presentation. Proper health education aimed at early detection and treatment in our environment is required

Patterns of malignant salivary gland tumours in Jos University Teaching Hospital (JUTH), Jos: A ten-year retrospective study

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