A five-year hedonic price breakdown for desktop personal computer attributes in Brazil

The purpose of this article is to identify the attributes that discriminate the prices of personal desktop computers. We employ the hedonic price method in evaluating such characteristics. This approach allows market prices to be expressed as a function, a set of attributes present in the products and services offered. Prices and characteristics of up to 3,779 desktop personal computers offered in the IT pages of one of the main Brazilian newspapers were collected from January 2003 to December 2007. Several specifications for the hedonic (multivariate) linear regression were tested. In this particular study, the main attributes were found to be hard drive capacity, screen technology, main board brand, random memory size, microprocessor brand, video board memory, digital video and compact disk recording devices, screen size and microprocessor speed. These results highlight the novel contribution of this study: the manner and means in which hedonic price indexes may be estimated in Brazil

Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment

Background: MicroRNAs (miRNAs) are short non-coding RNAs predicted to regulate one third of protein coding genes via mRNA targeting. In conjunction with key transcription factors, such as the repressor REST (RE1 silencing transcription factor), miRNAs play crucial roles in neurogenesis, which requires a highly orchestrated program of gene expression to ensure the appropriate development and function of diverse neural cell types. Whilst previous studies have highlighted select groups of miRNAs during neural development, there remains a need for amenable models in which miRNA expression and function can be analyzed over the duration of neurogenesis. Principal Findings: We performed large-scale expression profiling of miRNAs in human NTera2/D1 (NT2) cells during retinoic acid (RA)-induced transition from progenitors to fully differentiated neural phenotypes. Our results revealed dynamic changes of miRNA patterns, resulting in distinct miRNA subsets th

Glycogen level and UDP glucose: glycogen \u3b1-4-glucosyltransferase (EC 2.4.1.1) activity in the brains of rabbits after experimental circulatory hypoxia

Peer reviewed: YesNRC publication: Ye

ATP, ADP, AMP concentrations in rat brain following carbon monoxide intoxication and in experimental ischemia

NRC publication: Ye

The glycogen content, glycolytic and respiratory activity and ATP, ADP, AMP concentrations in rat brain following trichlorphon (dipterex) intoxication: Neuropathol.Pol.

NRC publication: Ye

The glycogen content and its topography and UDP glucose: glycogen \u3b1-4 glucosyltransferase (EC 2.4.1.11) activity in rat brain after experimental carbon monoxide intoxication

The glycogen content and its topography and the activity of UDPglucose-glycogen glucosyltransferase in the brain of rats after CO intoxication were investigated. A transient increase in glycogen content and in the enzyme activity was noticed. The highest level of glycogen was observed after 4h and the most significant increase of the enzyme activity after 2h, returning to normal values after 120 h. In the histochemical studies glycogen was deposited in the perivascular astrocytes, in their cytoplasm and astrocytic processes. These changes were localized in the cerebral and cerebellar cortex and in the grey formations of brain stem and were expressed mostly after 4, 6 and 12 h following CO intoxication.Peer reviewed: YesNRC publication: Ye

Apoptosis - related functional features of the DNAsel-like family of nucleases: Biochemistry

NRC publication: Ye

DNase I primary transcript is alternatively spliced in both normal and apoptotic cells: No evidence of upregulation in apoptosis: DNA Cell Biol.

NRC publication: Ye

Neurogenesis and neuronal communication on biocompatible neurochips

NRC publication: Ye

Protein kinase C delta and epsilon mediate VM26-induced apoptotic response of rodent fibroblasts: Cancer Lett.

NRC publication: Ye