Carotid plaque burden among patients with IFG, IGT and combination of IFG and IGT.

<p>Carotid plaque burden among patients with IFG, IGT and combination of IFG and IGT.</p

Glucose metabolic derangements and carotid plaque burden.

<p>Glucose metabolic derangements and carotid plaque burden.</p

Pertinent characteristics of patients divided according to their glucose metabolism.

<p>Pertinent characteristics of patients divided according to their glucose metabolism.</p

Baseline characteristics.

<p>Baseline characteristics.</p

Differences in z-score (number of SD from age corrected mean) of femoral neck bone mineral density according to serum 25-hydroxyvitamin D categories at baseline (N = 4782).

<p>Abbreviations: CI confidence interval.</p>1<p>F-test (type 3).</p>2<p>Adjusted for age at recruitment, sex (when all subjects are included), height, body mass index, current smoking, season of blood sampling and alcohol intake.</p>3<p>Additionally adjusted for current physical activity.</p

Hip fracture incidence (%) during a follow-up of 5.4 years (SD1.5) among AGES participants (N = 5461) according to serum baseline categories of 25(OH)D.

<p>Unadjusted values.</p

Hazard ratios for hip fractures according to serum 25-hydroxyvitamin D categories among all subjects (N = 5461), and stratified by sex.

<p>Abbreviations: HR Hazard Ratio, CI confidence interval.</p>1<p>Chi-square test (type 3).</p>2<p>Adjusted for age at recruitment, sex (when all subjects are included), height, body mass index, current smoking, season of blood sampling and alcohol intake.</p>3<p>Additionally adjusted for current physical activity.</p

PC-MRI for quantification of total CBF.

<p>(a) A PC-MRI scan for measuring mean tCBF was prescribed on a PC-MRI sagittal localizer image perpendicular to the carotid arteries at the level of the mid basilar artery. (b) A representative phase image demonstrating the right and left internal carotid arteries (R.ICA and L.ICA) together with the basilar artery (BA).</p

Representative CBF maps of one study participant.

<p>Representative CBF maps of an 80 year old male participant with whole brain CBF 47.6 and 49.5 ml/100g/min for the first and second scan at rest respectively. (a) First row corresponds to first scan at rest and (b) second row to rescan at rest.</p

Comparison of CBF values at rest and activation.

<p>(a) Average CBF maps of the entire study sample (n = 17) of the first scan at rest (Rest 1), rescan at rest (Rest 2) and at activation by bilateral finger-tapping (activation). (b) Comparison of CBF values at rest and activation by finger-tapping on a voxel level showed significantly higher perfusion during activation in the motor and somatosensory regions at threshold p≤0.01.</p