Fulminant Endogenous Anterior Uveitis due to Listeria monocytogenes

Purpose: To report an unusual case of fulminant anterior uveitis, confirmed as endogenous Listeria monocytogenes infection. Subject: A 67-year-old man with multiple comorbidities acutely developed a severe endogenous anterior uveitis. Results:L. monocytogenes, a ubiquitous Gram-positive bacillus, was directly indicated by culture and PCR. Early and aggressive treatment with intravenous antibiotics likely prevented the endophthalmitis which most cases on record experienced. Our patient regained satisfactory visual acuity. Conclusions: Prompt antimicrobial therapy is paramount when severe endogenous uveitis develops in a patient with comorbidities, especially with systemic immunosuppression. Treatment solely with corticosteroids should be avoided

Аудит промышленной безопасности предприятия

В данное время, когда фактически нет города, где бы не работали предприятия, особый смысл имеет промышленная безопасность. С каждым годом увеличивается количество опасных объектов. Исходя из этого, проблема с безопасностью возведена в ранг основных ценностей на государственном уровне. Часто в промышленно развитых странах установлен жесткий контроль лицензирования ОПО, строительства, эксплуатации и т.д. Безопасность сооружений в этих странах контролируется государственными органами. Промышленная безопасность опасных объектов - это определенная защита общества и страны от различных техногенных катастроф и аварий. Для того, чтобы обеспечить безопасность, проводится комплекс мероприятий, которые ориентированы, прежде всего, на обеспечение безопасности технических объектов. Все организации, которые эксплуатируют опасный производственный объект, должны временами производить вышесказанные мероприятия. Это указано в Федеральном законе «О промышленной безопасности опасных производственных объектов» Цель работы: проверка соответствия установленным требованиям ПБ, подготовка рекомендаций по устранению выявленных нарушений в УНДиПР МЧС России по Томской области.At the moment, when there is virtually no city, where enterprises would not work, industrial safety has a special meaning. Every year the number of dangerous objects increases. Proceeding from this, the security problem is elevated to the rank of basic values at the state level. Often in industrialized countries, strict control of GCO licensing, construction, operation, etc. is established. The safety of facilities in these countries is controlled by government agencies.Industrial safety of hazardous facilities is a certain protection of society and the country from various man-made disasters and accidents. In order to ensure safety, a set of measures is carried out, which are focused, first of all, on ensuring the safety of technical facilities. All organizations that operate a hazardous production facility must at times produce the aforesaid activities. This is indicated in the Federal Law "On Industrial Safety of Hazardous Production Facilities" The purpose of the work: verification of compliance with the established requirements of the PB, the preparation of recommendations for the elimination of identified violations in the UNDiPR of EMERCOM of Russia for the Tomsk region

Study of the dynamics of the accumulation of chemical elements by moss-transplants

Artificial retinal detachment is increasingly used in submacular surgery. However, overcoming physiological retinal adhesiveness by subretinal fluid injection is suspected to cause cellular damage and thus to limit visual rehabilitation. This experimental study was designed to examine the ultrastructural changes induced by retinal detachment under vitrectomy conditions and to evaluate factors that reduce adhesiveness and minimize cellular damage

Outcome of combined penetrating keratoplasty with vitreoretinal surgery for management of severe ocular injuries

To assess the effectiveness of a combined procedure (pars plana vitrectomy with temporary keratoprosthesis, vitreoretinal surgery, and penetrating keratoplasty) and to determine which factors influence corneal transplant success rates

Novel eccentric corneoscleral donor preparation technique providing corneoscleral tectonic and central split corneal grafts for multiple recipients

The vitamin D receptor (VDR) and aryl hydrocarbon receptor (AHR) are two nuclear receptors that exert their effects by binding with ligands and forming a molecular complex. These complexes translocate to the nucleus and activate the expression of a series of genes which have a response element to VDR or AHR. Both receptors have been identified in the pathogenesis of endometriosis, a common disease characterized by the formation of endometrium-like tissue in ectopic zones. Despite numerous therapies, there is no definitive cure for endometriosis at the pharmacological level. Our study aims to describe the location and the expression of VDR and AHR at the protein level. For this purpose, an evaluation was performed using tissue from the three normal phases of the endometrium (proliferative, early, and late secretory) and in endometriosis by immunohistochemistry, using anti-VDR and anti-AHR antibodies. We demonstrate that in the nuclei of glandular cells in endometriosis, the expression of VDR and AHR is mutually exclusive-when the expression of one receptor is high, the other one is low-suggesting a possible target in the treatment of endometriosis. We also identify a significant change in the expression of glandular cytoplasmic AHR between the proliferative and late secretory endometrium

Combined penetrating keratoplasty and vitreoretinal surgery with silicone oil: a 1-year follow-up

The aim of this study was to assess the functional outcome of eyes with corneal and vitreoretinal diseases following combined surgical procedures (pars plana vitrectomy with temporary keratoprosthesis, vitreoretinal surgery, and penetrating keratoplasty with intravitreal silicone oil tamponade) and to evaluate the factors preserving the clarity of grafts