Journal of African Christian Biography: v. 1, no. 7

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. Rainisoalambo, Ravelonjanahary, and Volahavana Germaine (Nenilava): Revival Leaders of Madagascar. 2. Rainisoalambo. 3. Ravelonjanahary. 4. Volahavana Germaine (Nenilava). 5. Recent Print and Digital Resourcews Related to Christianity in Africa

Journal of African Christian Biography: v. 5, no. 2

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: Women / Bilingual (French): 1. Biography of Émilienne Mboungou-Mouyabi (née Niangui Loubota), Congolese woman pastor, in ENGLISH and in FRENCH; 2. "Recovering the Lives of African Women Leaders in South Africa: The Case of Nokutela Dube" By Heather Hughes, chapter from African Christian Biography: Stories, Lives and Challenges, (D. L. Robert, editor); 3. "Notes on the Life History of the Reverend Canon Professor Emeritus John Samuel Pobee (1937 to 2020)"" by Casely Essamuah.; and, 4. "Theological Publishing and the Future of Christianity in Africa: African Theological Network Press" by Kyama Mugambi. 5. Book Notes, by Beth Restrick

Journal of African Christian Biography: v. 4, no. 2

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. Tributes to Lamin Sanneh by friends, family, colleagues, scholars, a Bible translator, and an editor. 2. Biographies by Lamin Sanneh in the DACB. 3. A selected bibliography by Lamin Sanneh, compiled by B. Restrick. 4. Book Notes, compiled by B. Restric

Original biographies from the Dictionary of African Christian Biography

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. The editors are pleased to offer the first annual cumulative volume of the Journal of African Christian Biography, the monthly scholarly publication that was launched in June of 2016. Since then, the life stories of twelve individuals who played vital roles in and through their faith communities have been published online as free downloads. But it is important that a selection of DACB stories be more readily available to those without access to the internet. As I mentioned in the fall 2016 newsletter of the DACB, each issue of the journal is available in its e-journal, on-line version, where it is configured either as A4 or 8.5 x 11 format printable as booklets, ready for local printing and binding or stapling. Our intention is to make it easy for academics and church leaders in various parts of Africa to make print copies of the journal available to their students, colleagues or church members. And so it is with this cumulative volume.This issue focuses on: 1. "Walatta Petros and Hakalla Amale, Pious Women of Ethiopia," with commentary by Dr. Jonathan Bonk, Project Director. 2. Walatta Petros. 3. Hakalla Amale. 4. Bishop Josiah Kibira of Tanzania, Ecumenical Statesman. 5. Josiah Mutabuzi Isaya Kibira. 6. Josiah Kibira. 7. David Lonkibiri Windibiziri. 8. Abiodun Babatunde Lawrence. 9. Dominic Ignatius Ekandem. 10. William Wadé Harris, Prophet-Evangelist of West Africa: His Life, Message, Praxis, Heritage, and Legacy. 11. William Wadé Harris. 12. Michael Timneng and Jeremiah Chi Kangsen: Christianity Beyond the Missionary Presence in Cameroon. 13. Michael Timneng. 14. Jeremiah Chi Kangsen. 15. Rainisoalambo, Ravelonjanahary, and Volahavana Germaine (Nenilava): Revival Leaders of Madagascar. 16. Rainisoalambo. 17. Ravelonjanahary. 18. Volahavana Germaine (Nenilava). 19. Recent Print and Digital Resourcews Related to Christianity in Africa

Ultra-deep sequencing confirms immunohistochemistry as a highly sensitive and specific method for detecting BRAF V600E mutations in colorectal carcinoma

The activating BRAF V600 mutation is a well-established negative prognostic biomarker in metastatic colorectal carcinoma (CRC). A recently developed monoclonal mouse antibody (clone VE1) has been shown to detect reliably BRAF V600E mutated protein by immunohistochemistry (IHC). In this study, we aimed to compare the detection of BRAF V600E mutations by IHC, Sanger sequencing (SaS), and ultra-deep sequencing (UDS) in CRC. VE1-IHC was established in a cohort of 68 KRAS wild-type CRCs. The VE1-IHC was only positive in the three patients with a known BRAF V600E mutation as assessed by SaS and UDS. The test cohort consisted of 265 non-selected, consecutive CRC samples. Thirty-nine out of 265 cases (14.7%) were positive by VE1-IHC. SaS of 20 randomly selected IHC negative tumors showed BRAF wild-type (20/20). Twenty-four IHC-positive cases were confirmed by SaS (24/39; 61.5%) and 15 IHC-positive cases (15/39; 38.5%) showed a BRAF wild-type by SaS. UDS detected a BRAF V600E mutation in 13 of these 15 discordant cases. In one tumor, the mutation frequency was below our threshold for UDS positivity, while in another case, UDS could not be performed due to low DNA amount. Statistical analysis showed sensitivities of 100% and 63% and specificities of 95 and 100% for VE1-IHC and SaS, respectively, compared to combined results of SaS and UDS. Our data suggests that there is high concordance between UDS and IHC using the anti-BRAFV600E (VE1) antibody. Thus, VE1 immunohistochemistry is a highly sensitive and specific method in detecting BRAF V600E mutations in colorectal carcinom

Journal of African Christian Biography: v. 7, no. 1

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: Focus: Archbishop Desmond Tutu (South Africa) and Msgr. Tharcisse Tshibangu (DRC); Deji Isaac Ayegboyin (Nigeria); Women’s stories (Kenya and Zimbabwe) 1. Introduction: Activism, Theology, and Witness with an African Color. 2. Tribute Archbishop Desmond Tutu (1931-2021) & South African Black Theology By Francis Anekwe Oborji. 3. Appendix: A Brief Biography of Desmond Tutu’s Life. 4. Tribute Msgr. Tharcisse Tshibangu (1933 – 2021): Promoter of Theology with an “African Color” By Francis Anekwe Oborji. 5. Interview with Deji Isaac Ayegboyin, DACB Pioneer and Facilitator in Nigeria. 6. Book Review The Power of the Word, *A History of the Seventh-day Adventism in Central Kenya*: Highlighting the Role of Mama Eunice Njoki Wangai By Mary Getui. 7. “Why Can’t We Ordain Nellie?”: Leadership, Faith, and Hagiography in the Life of Nellie Maduma Mlotshwa, Zimbabwe By Wendy Urban-Mead. 8. “A Character Worth Writing About”: Sikhawulaphi Khumalo’s Education and Christian Experiences at Empandeni Mission, Southwestern Zimbabwe, 1900–1940s By Barbara Mahamba. 9. Recent Print and Digital Resources Related to Christianity in Africa Compiled by Beth Restrick, Head, BU African Studies Library

Journal of African Christian Biography: v. 5, no. 3

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. "Tribute: Legendary Pioneer African Theologian Charles Nyamiti" by Francis Anekwe Oborji; 2. "'Jesus! Say It Once Again and the Matter Is Settled': The Life and Legacy of Oral Theologian Madam Afua Kuma of Ghana (1908-1987)" by Sara J. Fretheim; 3. Interview of Dr. Emmanuel Evans-Anfom by Dr. Esther Ecolatse; 4. Interview of Cardinal Christian Wiyghan Tumi by Prof. Paul Nkwi; 5. Remembering Paul Dayhoff; 6. Book Notes, by Beth Restrick

Ultra-deep sequencing confirms immunohistochemistry as a highly sensitive and specific method for detecting BRAF (V600E) mutations in colorectal carcinoma

The activating BRAF (V600) mutation is a well-established negative prognostic biomarker in metastatic colorectal carcinoma (CRC). A recently developed monoclonal mouse antibody (clone VE1) has been shown to detect reliably BRAF (V600E) mutated protein by immunohistochemistry (IHC). In this study, we aimed to compare the detection of BRAF (V600E) mutations by IHC, Sanger sequencing (SaS), and ultra-deep sequencing (UDS) in CRC. VE1-IHC was established in a cohort of 68 KRAS wild-type CRCs. The VE1-IHC was only positive in the three patients with a known BRAF (V600E) mutation as assessed by SaS and UDS. The test cohort consisted of 265 non-selected, consecutive CRC samples. Thirty-nine out of 265 cases (14.7 %) were positive by VE1-IHC. SaS of 20 randomly selected IHC negative tumors showed BRAF wild-type (20/20). Twenty-four IHC-positive cases were confirmed by SaS (24/39; 61.5 %) and 15 IHC-positive cases (15/39; 38.5 %) showed a BRAF wild-type by SaS. UDS detected a BRAF (V600E) mutation in 13 of these 15 discordant cases. In one tumor, the mutation frequency was below our threshold for UDS positivity, while in another case, UDS could not be performed due to low DNA amount. Statistical analysis showed sensitivities of 100 % and 63 % and specificities of 95 and 100 % for VE1-IHC and SaS, respectively, compared to combined results of SaS and UDS. Our data suggests that there is high concordance between UDS and IHC using the anti-BRAF(V600E) (VE1) antibody. Thus, VE1 immunohistochemistry is a highly sensitive and specific method in detecting BRAF (V600E) mutations in colorectal carcinoma

Journal of African Christian Biography: v. 6, no. 4

A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: Tributes to Andrew Walls and Benedict Ssettuuma (Uganda); Samuel T. O. Akande (Nigeria). This issue of the Journal of African Christian Biography honors the memory of "Prof." Andrew Finlay Walls and Fr. Benedict Ssettuuma, Jr. It also celebrates the contribution of Dr. Michael Adeleke Ogunewu to the work of the DACB both as an author and a mentor-teacher. One of his biographies, that of Samuel T. O. Akande, is included. The issue also includes a serialized chapter from African Christian Biography by Roger Levine and a new section, "Teaching with the DACB," featuring the reflections of a North American student on what the DACB has taught her

All-sky search for long-duration gravitational wave transients with initial LIGO

We present the results of a search for long-duration gravitational wave transients in two sets of data collected by the LIGO Hanford and LIGO Livingston detectors between November 5, 2005 and September 30, 2007, and July 7, 2009 and October 20, 2010, with a total observational time of 283.0 days and 132.9 days, respectively. The search targets gravitational wave transients of duration 10-500 s in a frequency band of 40-1000 Hz, with minimal assumptions about the signal waveform, polarization, source direction, or time of occurrence. All candidate triggers were consistent with the expected background; as a result we set 90% confidence upper limits on the rate of long-duration gravitational wave transients for different types of gravitational wave signals. For signals from black hole accretion disk instabilities, we set upper limits on the source rate density between 3.4×10-5 and 9.4×10-4 Mpc-3 yr-1 at 90% confidence. These are the first results from an all-sky search for unmodeled long-duration transient gravitational waves. © 2016 American Physical Society