Survival probabilities and Hazard Ratios for all cause mortality by pN classification and LNR.

*<p>Model A is adjusted for: age, radiotherapy, surgery type, grade and tumor size and pN stage and stratified by ER Status. Model B is adjusted for: age, radiotherapy, surgery type, grade and tumor size and LNR and stratified by ER Status. Both models were internally validated using bootstrap resampling.</p

Subgroup analysis to check the added prognostic value of LNR over pN within specific subgroups.

a<p>Model adjusted for age at diagnosis, chemotherapy, radiotherapy, surgery type, grade and tumor size and stratified by ER status.</p>b<p>Model adjusted for age at diagnosis, chemotherapy, surgery type and tumor size.</p>c<p>Model adjusted for age at diagnosis, chemotherapy, radiotherapy, surgery type and tumor size and stratified by ER status. All models were internally validated using bootstrap resampling.</p

Patient, tumor characteristics and treatment along with the unadjusted Hazard Ratio for all cause mortality.

*<p>indicates valid proportions have been calculated (i.e., not considering unknown).</p

Risk reclassification table at 3 years of follow up based on models including pN stage and LNR respectively.

<p>Net Reclassification Index (NRI) = 3.2% (p value 0.08). Patients are categorized into risk categories of death based on their individual survival probabilities obtained from models A and B such that a patient with a high survival probability is categorized into the ‘low risk of death’ group and so on.</p

Cumulative overall survival by ethnicity in 5,264 South East Asian women with breast cancer.

<p>Cumulative overall survival by ethnicity in 5,264 South East Asian women with breast cancer.</p

Association between Ethnicity and All-Cause Mortality Following Diagnosis with Breast Cancer in 5,264 Southeast Asian Women.

a<p>Estimated from Cox regression model adjusted for age at diagnosis, center, and year of diagnosis.</p>b<p>Estimated from Cox regression model adjusted for age at diagnosis, center, year of diagnosis, tumor size, lymph node involvement, distant metastasis, estrogen receptor status, progesterone receptor status, and tumor grade.</p>c<p>Estimated from Cox regression model adjusted for age at diagnosis, center, year of diagnosis, tumor size, lymph node involvement, distant metastasis, estrogen receptor status, progesterone receptor status, tumor grade, loco-regional therapy, chemotherapy, and hormone therapy.</p

Distribution of Patient Profile, Tumor Characteristics and Treatment According to Ethnicity in 5,264 Southeast Asian Women with Breast Cancer.

a<p>Column percentage is presented except for center where row percentage is presented.</p>b<p>Compared using χ² test for categorical variables and Kruskal Wallis test for continuous variables.</p>c<p>Absolute tumor size was only available in 4 359 patients i.e. in 80.4% of the Chinese, 89.2% of Malays and 88.5% of Indians.</p>d<p>Only includes 4,589 patients with TNM stage I to stage III breast cancer. Complete treatment consists of mastectomy, or breast conserving surgery followed by radiotherapy. Incomplete treatment includes breast conserving surgery only or radiotherapy only.</p>e<p>Only includes 2 772 patients with estrogen or progesterone receptor positive tumors.</p