A Bayesian approach to high fidelity interferometric calibration II: demonstration with simulated data

In a companion paper, we presented BayesCal, a mathematical formalism for mitigating sky-model incompleteness in interferometric calibration. In this paper, we demonstrate the use of BayesCal to calibrate the degenerate gain parameters of full-Stokes simulated observations with a HERA-like hexagonal close-packed redundant array, for three assumed levels of completeness of the a priori known component of the calibration sky model. We compare the BayesCal calibration solutions to those recovered by calibrating the degenerate gain parameters with only the a priori known component of the calibration sky model both with and without imposing physically motivated priors on the gain amplitude solutions and for two choices of baseline length range over which to calibrate. We find that BayesCal provides calibration solutions with up to four orders of magnitude lower power in spurious gain amplitude fluctuations than the calibration solutions derived for the same data set with the alternate approaches, and between $\sim10^7$ and $\sim10^{10}$ times smaller than in the mean degenerate gain amplitude on the full range of spectral scales accessible in the data. Additionally, we find that in the scenarios modelled only BayesCal has sufficiently high fidelity calibration solutions for unbiased recovery of the 21 cm power spectrum on large spectral scales ($k_\parallel \lesssim 0.15~h\mathrm{Mpc}^{-1}$). In all other cases, in the completeness regimes studied, those scales are contaminated

R&D for Positron Sources at High-Energy Lepton Colliders

Several designs for high-energy Lepton Colliders serving as Higgs factories but extendable to higher energies up to the TeV range are under discussion. The most mature design is the International Linear Collider (ILC), but also the Compact Linear Collider (CLIC) as well as the new concept of a Hybrid Asymmetric Linear Higgs Factory (HALHF) have a large physics potential. The first energy stage with $\sqrt{s}=250$~GeV requires high luminosity and polarized beams and imposes an effort for all positron source designs at high-energy colliders. In the baseline design of the ILC, an undulator-based source is foreseen for the positron source in order to match the physics requirements. In this contribution an overview is given about the undulator-based source, the target tests, the rotating target wheel design, as well as the pulsed solenoid and the new technology development of plasma lenses as optic matching devices.Comment: 14 pages, 17 figures, talk presented at the International Workshop on Future Linear Colliders (LCWS2023), 15-19 May 2023. C23-05-15.

Long-term forecasting technology of macroeconomic systems development: regional aspect

Conducting of effective public policy is impossible without the scientifically substantiated evaluation of taken decisions. Long-term modeling and forecasting is the tool that allows evaluating the impact of the ongoing reforms on macroeconomic systems’ development. This requires the processing of huge amount of diverse information. This article is devoted to modeling and long-term forecasting of regional macroeconomic systems’ development. The simulation model based on the method of system dynamics is proposed. The generalized forecasting technology, which includes simulation model setup, validation and long-term forecasting, is developed. The numerical experiments and the forecast of Kharkiv region development until 2025 were carried out on the basis of the suggested information technology

Status of the undulator-based ILC positron source

The design of the positron source for the International Linear Collider (ILC) is still under consideration. The baseline design plans to use the electron beam for the positron production before it goes to the IP. The high-energy electrons pass a long helical undulator and generate an intense circularly polarized photon beam which hits a thin conversion target to produce $e^+e^-$ pairs. The resulting positron beam is longitudinally polarized which provides an important benefit for precision physics analyses. In this paper the status of the design studies is presented with focus on ILC250. In particular, the target design and cooling as well as issues of the optical matching device are important for the positron yield. Some possibilities to optimize the system are discussed.Comment: Talk presented at the International Workshop on Future Linear Colliders (LCWS2018), Arlington, Texas, 22-26 October 2018. C18-10-2

A biomanufacturing facility based on continuous processing and single use technology

Bayers vision of the Biofacility of the Future is developed within the Mobidik project. A pilot plant with a complete production line of monoclonal antibodies from fermentation to final drug substance has been established. All parts in contact with the product are made in single use technology and the process is run as an integrated, fully continuous process. The process control system and the PAT concept are developed to achieve a high level of automation limiting the need for manual handling to a minimum. Issues related to GMP compliance are being addressed at an early stage. A detailed GMP risk analysis and a concept for product release are being developed. The pilot plant is used to provide a proof of concept for the process technology and to lay the foundation for building a production plant with a capacity of 150 kg/a. In particular, the pilot plant is used to demonstrate process robustness and GMP readiness. The concept for the production plant is based on the four design criteria; 100% single use equipment, continuous processing, closed processing and “ballroom” production. Compared to traditional facilities this concept is significantly less complex which results in a number of benefits. The engineering, construction, commissioning, qualification and validation of the facility are much faster. Flexibility is achieved through the decoupling of the equipment from the building. The facility is smaller, has reduced investment and production cost as well as reduced energy and water consumption. It should therefore be possible to build the production facility in less than two years for less than 20 million €

An integrated marine data collection for the German Bight – Part 1: Subaqueous geomorphology and surface sedimentology (1996–2016)

Datasets: Themengebiet - Geomorphologie - https://doi.org/10.48437/02.2020.K2.7000.0001Datasets: Themengebiet - Bathymetrie - https://doi.org/10.48437/02.2020.K2.7000.0002Datasets: Themengebiet - Sedimentologie - https://doi.org/10.48437/02.2020.K2.7000.000