189 research outputs found
No art left behind : the state of arts education today and solutions for tomorrow
Due to the lack of funding and the implementation of standardized testing, arts education is diminishing from the curriculum in many elementary schools. Unfortunately, the loss of arts in the classroom negatively impacts children’s development, the use of their creative minds and their academic success. Local art organization and program leaders were interviewed about the state of arts education in our schools, speaking out about how their programs are helping to expose children to art and what needs to be done to integrate art into the classroom. Preliminary data analysis indicates that local art organizations are providing art to children that do not receive arts education in their schools. The local art organization directors also believe that arts education is important to a student’s well-rounded education. As a result of this project, members of the local area were urged to make a change to the current structure of arts education by contacting their local congressmen about the importance of the issue
Prader-Willi Syndrome : Adrnarche, gonadal function, cognition, psychosocial aspects and effects of growth hormone treatment in children
The first patient with Prader-Willi syndrome (PWS), described in 1887 by Langdon-Down1
(Figure 1), was an adolescent girl with mental impairment, short stature, hypogonadism, and
obesity. The first official group of patients with PWS was described by endocrinologists Prader,
Labhart, and Willi in 19562. They described an unusual pattern of abnormalities, including
neonatal hypotonia resulting in feeding problems in infancy, cryptorchidism, short stature and
retarded bone age, small hands and feet, delayed developmental milestones, characteristic
faces, cognitive impairment, onset of gross obesity in early childhood due to insatiable hunger,
and a tendency to develop diabetes in adolescence and adulthood when weight was not
controlled.
Behavioral and psychological problems associated with PWS were not described until the
1980s3.
Since these first reports, knowledge on different aspects of the syndrome has vastly increased,
although a lot of questions still remained and needed to be further investigated.
This chapter describes the genetic basis of PWS, clinical manifestations in different stages
of life, the hypothalamus and pituitary, and growth hormone (GH) treatment in children with
PWS. It further describes a summary of the results from the Dutch national growth hormone
trial for children with Prader-Willi syndrome from 2002 to 2009 and characteristics of PWS
within the scope of this thesis. Finally, the objectives of the studies described in the various
chapters of this thesis will be presented
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