Synthesis of Cyclopropanes via Organoiron Methodology: Preparation of \u3cem\u3erac\u3c/em\u3e-Dysibetaine Cpa

The cyclopropane containing betaine, rac-dysibetaine CPa, was prepared from (1-methoxycarbonylpentadienyl)-Fe(CO)2PPh3+ by nucleophilic addition of nitromethane anion followed by oxidatively induced reductive elimination

Crystal and molecular structure of bis(8-phenylmenthyl) 2-(2-methyl-5-oxo-3-cyclohexen-1-yl)propandioate, C\u3csub\u3e42\u3c/sub\u3eH\u3csub\u3e54\u3c/sub\u3eO\u3csub\u3e5\u3c/sub\u3e• CH\u3csub\u3e3\u3c/sub\u3eCN

The X-ray crystal structure of the title compound, as crystallized from acetonitrile-water was determined. The relative stereochemistry of the cyclohexenone ring with respect to the 8-phenylmenthyl esters was determined. The title compound crystallizes in the noncentrosymmetric space group P21, with a=8.9850(10) Å, b=15.575(3) Å, c=14.478(2) Å, β=94.61(2)°, and D calc=1.118 g cm−3 for Z=2

Host–Guest Complex of β-Cyclodextrin and Disulfide Form of 4-Aminothiophenol

An inclusion complex of β-cyclodextrin and 4-aminothiophenol was assembled by hydrophobic interaction of the host (β-cyclodextrin) and guest (4-aminothiophenol). The complex was isolated as crystalline solid and studied by single crystal X-ray diffraction method along with NMR and IR spectroscopy. Two cyclodextrin rings each containing one disulfide form of 4-aminothiophenol were found to pair up by hydrogen bonding of the outer rim -OH groups. The phenyl disulfide moiety of 4-aminophenyl disulfide molecule was found in the core of β-cyclodextrin, while the amino functional groups were positioned to the exterior of the cyclodextrin ring. Phenyl rings of the guest molecule from each partner of the paired cyclodextrin complex were found parallel to each other, indicating possible π-π stacking interaction between them

Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol

This article describes one-pot synthesis of new fluorinated hexahydroquinoline derivatives via unsymmetric Hantzsch reaction involving 5-trifluoromethyl-1,3-cyclohexanedione, aldehydes, acetoacetate ester, and ammonium acetate in trifluoroethanol (TFE). The reaction is simple and rapid with high yield

Double Carbon−Hydrogen Activation of 2-Vinylpyridine: Synthesis of Tri- and Pentanuclear Clusters Containing the μ-NC\u3csub\u3e5\u3c/sub\u3eH\u3csub\u3e4\u3c/sub\u3eCH═C Ligand

Reactions of 2-vinylpyridine with the triruthenium complexes [Ru3(CO)12] and [Ru3(CO)10(μ-dppm)] leads to a previously unknown double carbon−hydrogen bond activation of the β-carbon of the vinyl group to afford the pentaruthenium and triruthenium complexes [Ru5(CO)14(μ4-C5H4CH═C)(μ-H)2] (1) and [Ru3Cl(CO)5(μ-CO)(μ-dppm)(μ3-NC5H4CH═C)(μ-H)] (2), respectively. Crystal structures reveal two different forms of bridging of the dimetalated 2-vinylpyridyl ligand, capping a square face in 1 and a triangular face in 2

Reactions of Rhenium and Manganese Carbonyl Complexes with 1,8-bis(diphenylphosphino)naphthalene: Ligand Chelation, C–H and C–P bond-cleavage Reactions

Reaction of [Re2(CO)8(MeCN)2] with 1,8-bis(diphenylphosphino)naphthalene (dppn) afforded three mono-rhenium complexes fac-[Re(CO)3(κ1:η1-PPh2C10H6)(PPh2H)] (1), fac-[Re(CO)3{κ1:κ1:η1-(O)PPh2C10H6(O)PPh(C6H4)}] (2) and fac-[ReCl(CO)3(κ2-PPh2C10H6PPh2)] (3). Compounds 1–3 are formed by Re–Re bond cleavage and P–C and C–H bond activation of the dppn ligand. Each of these three complexes have three CO groups arranged in facial fashion. Compound 1 contains a chelating cyclometalated diphenylnaphthylphosphine ligand and a terminally coordinated PPh2H ligand. Compound 2 consists of an orthometalated dppn-dioxide ligand coordinated in a κ1:κ1:η1-fashion via both the oxygen atoms and ortho-carbon atom of one of the phenyl rings. Compound 3 consists of an unchanged chelating dppn ligand and a terminal Cl ligand. Treatment of [Mn2(CO)8(MeCN)2] with a slight excess of dppn in refluxing toluene at 72 °C, gave the previously reported [Mn2(CO)8(μ-PPh2)2] (4), formed by cleavage of C–P bonds, and the new compound fac-[MnCl(CO)3(κ2-PPh2C10H6PPh2)] (5), which has an unaltered chelating dppn and a terminal Cl ligand. In sharp contrast, reaction of [Mn2(CO)8(MeCN)2] with slight excess of dppn at room temperature yielded the dimanganese [Mn2(CO)9{κ1-PPh2(C10H7)}] (6) in which the diphenylnaphthylphosphine ligand, formed by facile cleavage of one of the P–C bonds, is axially coordinated to one Mn atom. Compound 6 was also obtained from the reaction of [Mn2(CO)9(MeCN)] with dppn at room temperature. The XRD structures of complexes 1–3, 5, 6 are reported

Study of relationship between age and body mass index on knee osteoarthritis in advanced aged females in a divisional city of Bangladesh

Background: Knee osteoarthritis is a notable issue in senior citizens and is a burning problem worldwide. There are so many risk factors related to knee osteoarthritis but women's sex, age, and obesity are significant. The aim and objective of this study were to estimate the prevalence of knee osteoarthritis among women in the age group of 46 to 65 years and the effect of age and body mass index (BMI) on knee osteoarthritis.Methods: Cross-sectional study was conducted at outpatient department (OPD) in Mymensingh Medical College Hospital, a tertiary level hospital, among females of Mymensingh, a divisional city of Bangladesh in the age group of 46 to 65 years. Purposive sampling technique used to select study subjects. A total of 100 females participated in this study in one month (July 2019-August 2019).Results: 100 participants were enlisted in the study, in the age group of 46 to 55 years 39 (39%) and 56 to 65 years 61 (61%). Total 65 (65%) participants were affected with knee osteoarthritis. Among them, 19 (29.2%) participants were in the age group of 46-55 years and 46 (70.8%) participants were in the age group of 55-65 years, thus in the advanced age group, knee osteoarthritis is remarkably more. Participants affected with knee osteoarthritis with BMI ≥25 were significantly more affected 45 (69.2%) compared with participants with normal BMI 20 (30.2%).Conclusions: Knee osteoarthritis is significantly associated with advanced age and obesity. Advanced age and overweight were strongly associated with osteoarthritis in our population. Therefore, weight reduction and preventive measures can decrease the burden and will help in minimizing morbidity associated with OA

X-ray Structure of \u3cem\u3emer\u3c/em\u3e-[Mo(CO)\u3csub\u3e3\u3c/sub\u3e(PPh\u3csub\u3e3\u3c/sub\u3e)(\u3cem\u3eκ\u3c/em\u3e\u3csup\u3e2\u3c/sup\u3e-dppm)]

Treatment of [Mo(CO)3(NCMe)3] with bis(diphenylphosphino)methane (dppm) and triphenylphosphine (PPh3) at 50 °C afforded mer-[Mo(CO)3(PPh3)(κ2-dppm)] (1) in 55% yield which has been characterized by single crystal X-ray diffraction studies and spectroscopic measurements. Compound 1 crystallizes in the triclinic space group P−1 with a = 10.3449(6), b = 11.1570(6), c = 17.8961(10) Å, β = 80.8400(10)°, Z = 2 and V = 1959.8(2) Å3

Valuable components of bambangan fruit (Mangifera pajang) and its coproducts: a review

Fruits are important food commodities that can be consumed either raw or processed and are valued for their taste, nutrients, and healthy compounds. Mangifera pajang Kosterm (bambangan) is an underutilized fruit found in Malaysia (Sabah and Sarawak), Brunei, and Indonesia (Kalimantan). It is highly fibrous and juicy with an aromatic flavour and strong smell. In recent years, bambangan fruit has been gaining more attention due to its high fibre, carotenoid content, antioxidant properties, phytochemicals, and medicinal usages. Therefore, the production, trade, and consumption of bambangan fruit could be increased significantly, both domestically and internationally, because of its nutritional value. The identification and quantification of bioactive compounds in bambangan fruit has led to considerable interest among scientists. Bambangan fruit and its waste, especially its seeds and peels, are considered cheap sources of valuable food and are considered nutraceutical ingredients that could be used to prevent various diseases. The use of bambangan fruit waste co-products for the production of bioactive components is an important step towards sustainable development. This is an updated report on the nutritional composition and health-promoting phytochemicals of bambangan fruit and its co-products that explores their potential utilization. This review reveals that bambangan fruit and its co-products could be used as ingredients of dietary fibre powder or could be incorporated into food products (biscuits and macaroni) to enhance their nutraceutical properties