The "Coulomb phase" in frustrated systems

The "Coulomb phase" is an emergent state for lattice models (particularly highly frustrated antiferromagnets) which have local constraints that can be mapped to a divergence-free "flux". The coarse-grained version of this flux or polarization behave analogously to electric or magnetic fields; in particular, defects at which the local constraint is violated behave as effective charges with Coulomb interactions. I survey the derivation of the characteristic power-law correlation functions and the pinch-points in reciprocal space plots of diffuse scattering, as well as applications to magnetic relaxation, quantum-mechanical generalizations, phase transitions to long-range-ordered states, and the effects of disorder.Comment: 30 pp, 5 figures (Sub. to Annual Reviews of Condensed Matter Physics

Ising pyrochlore magnets: Low temperature properties, ice rules and beyond

Pyrochlore magnets are candidates for spin-ice behavior. We present theoretical simulations of relevance for the pyrochlore family R2Ti2O7 (R= rare earth) supported by magnetothermal measurements on selected systems. By considering long ranged dipole-dipole as well as short-ranged superexchange interactions we get three distinct behaviours: (i) an ordered doubly degenerate state, (ii) a highly disordered state with a broad transition to paramagnetism, (iii) a partially ordered state with a sharp transition to paramagnetism. Thus these competing interactions can induce behaviour very different from conventional ``spin ice''. Closely corresponding behaviour is seen in the real compounds---in particular Ho2Ti2O7 corresponds to case (iii) which has not been discussed before, rather than (ii) as suggested earlier.Comment: 5 pages revtex, 4 figures; some revisions, additional data, additional co-authors and a changed title. Basic ideas of paper remain the same but those who downloaded the original version are requested to get this more complete versio

Influence of magnetic field strength of hybrid magnet on vibration isolation of quarter car model

This work studies the vibration isolation of a single degree of freedom (SDOF) quarter car model under the influence of the magnetic field strength of electromagnet of a hybrid electromagnet (EM) and permanent magnet (PM) combination. Furthermore, the time history plot helps to study the influence of the relative movement of the electromagnet and the permanent magnet on the top plate, base plate, stiffness of the system and damping coefficient. A laboratory scale model of a SDOF quarter car with a hybrid magnet is tested on an open loop type shaker table at different frequencies of base excitation. Data acquisition and analysis have been carried out with the aid of two piezoelectric accelerometers and Lab VIEW software. Also, the theoretical analysis is carried out in MATLAB Simulink. From the experimental and Simulink results, it is found that the repulsive force between the electromagnet and permanent magnet varies the base and top plate amplitude, the stiffness of the system and damping coefficient of the suspension elements

Spirograph based electrospinning system for producing fibre mat with near uniform mechanical property

This study focuses on the development of Spirograph-based mechanical system (SBMS) for the collection ofpolyacrylonitrile fibres in an electrospinning process. The collector plate is set to trace a spiropath in such a way that theevent of crossing the centre of collection region from different radial direction is high. To assess the capability of SBMS,electrospun mat of acrylic has been prepared and the properties of samples sectioned from different angular positions of acircular mat are evaluated. The diameter and alignment of fibres are analyzed by processing the scanning electronmicroscopy (SEM) images of electrospun mats with the use of ImageJ software. The electrospun mat produced using SBMScollector assembly exhibits near uniform characteristics like thickness, tensile strength, porosity, fibre diameter and fibrealignment as compared to the electrospun mat produced by using conventional static collector

Defining novel functions for cerebrospinal fluid in ALS pathophysiology

Despite the considerable progress made towards understanding ALS pathophysiology, several key features of ALS remain unexplained, from its aetiology to its epidemiological aspects. The glymphatic system, which has recently been recognised as a major clearance pathway for the brain, has received considerable attention in several neurological conditions, particularly Alzheimer's disease. Its significance in ALS has, however, been little addressed. This perspective article therefore aims to assess the possibility of CSF contribution in ALS by considering various lines of evidence, including the abnormal composition of ALS-CSF, its toxicity and the evidence for impaired CSF dynamics in ALS patients. We also describe a potential role for CSF circulation in determining disease spread as well as the importance of CSF dynamics in ALS neurotherapeutics. We propose that a CSF model could potentially offer additional avenues to explore currently unexplained features of ALS, ultimately leading to new treatment options for people with ALS.</p

Quantum and thermal spin relaxation in diluted spin ice: Dy(2-x)MxTi2O7 (M = Lu, Y)

We have studied the low temperature a.c. magnetic susceptibility of the diluted spin ice compound Dy(2-x)MxTi2O7, where the magnetic Dy ions on the frustrated pyrochlore lattice have been replaced with non-magnetic ions, M = Y or Lu. We examine a broad range of dilutions, 0 <= x <= 1.98, and we find that the T ~ 16 K freezing is suppressed for low levels of dilution but re-emerges for x > 0.4 and persists to x = 1.98. This behavior can be understood as a non-monotonic dependence of the quantum spin relaxation time with dilution. The results suggest that the observed spin freezing is fundamentally a single spin process which is affected by the local environment, rather than the development of spin-spin correlations as earlier data suggested.Comment: 26 pages, 9 figure

Trials for neurodegenerative diseases:time to innovate

The remarkable progress in our understanding of the mechanisms underlying neurodegenerative diseases heralds an era when neurologists would be at the vanguard of regenerative medicine, instead of chroniclers of decline. To capitalise on these advances that are identifying ever more therapeutic candidates, whether repurposed or entirely new, there is an urgent need for refined methods to test these putative medicines in clinical trials. Our field has the opportunity to learn from innovations in trial design, particularly those pioneered in oncology

Ordering of the pyrochlore Ising model with the long-range RKKY interaction

The ordering of the Ising model on a pyrochlore lattice interacting via the long-range RKKY interaction, which models a metallic pyrochlore magnet such as Pr_2Ir_2O_7, is studied by Monte Carlo simulations. Depending on the parameter k_F representing the Fermi wavevector, the model exhibits rich ordering behaviors