S. Johannes in Jerusalem Church: enhancement through technological analysis

The research aims to exhaust the store of knowledge on a nearly one thousand years monument through the study and the interpretation of ancient technological devices that have generated unique formal characteristics. The analysis on the church of the Castello della Magione in Poggibonsi, monumental complex near the ancient Via Francigena, face the evolutionary history in an attempt to fill the lack of documentation. Critical observation of the monument, direct survey of technological and structural devices, punctual measurements aimed at verifying the hypothesis, reconstruction carried out in the field and reworking of data in post-production are the distinctive characteristics of the search method. In particular, we have achieved the following results: hypothesis of self-supporting during construction of a brick vault not coeval with the church; formal interpretation of the unique denticular single-lancet window of the church’s main front, that has so far left scholars' curiosity unsatisfied; detection of the method for tracking the monument and the proportional relationships used to its location in relation to the existing context; he explanation of the peculiar and irregular orientation of the church; assumptions about the dating of the monument, still uncertain because of the lack of documents; in general, the complete knowledge of the monument aimed to provide useful tools for the enhancement and for a correct approach in case of any restoration

S. Johannes in Jerusalem Church: enhancement through technological analysis

<p>The research aims to exhaust the store of knowledge on a nearly one thousand years monument through the study and the interpretation of ancient technological devices that have generated unique formal characteristics. The analysis on the church of the Castello della Magione in Poggibonsi, monumental complex near the ancient Via Francigena, face the evolutionary history in an attempt to fill the lack of documentation. Critical observation of the monument, direct survey of technological and structural devices, punctual measurements aimed at verifying the hypothesis, reconstruction carried out in the field and reworking of data in post-production are the distinctive characteristics of the search method. In particular, we have achieved the following results: hypothesis of self-supporting during construction of a brick vault not coeval with the church; formal interpretation of the unique denticular single-lancet window of the church’s main front, that has so far left scholars' curiosity unsatisfied; detection of the method for tracking the monument and the proportional relationships used to its location in relation to the existing context; he explanation of the peculiar and irregular orientation of the church; assumptions about the dating of the monument, still uncertain because of the lack of documents; in general, the complete knowledge of the monument aimed to provide useful tools for the enhancement and for a correct approach in case of any restoration.</p

NEW TECHNOLOGIES FOR FUTURE LIVING. A proposal for 2100s Milan.

Evolutionary dynamics and the current environmental, social and economic emergencies envisage new urban visions requiring designers to shift the reference time’s horizon towards long-period scenarios. The contribution refers to this context with the aim to investigate future inhabiting presenting the results of a design experience of urban regeneration led in Milan for RELIVE 2019 competition. The project draws inspiration from last century’s utopian cities visions and is developed based on an Amplified Requirements Framework projected towards long-term scenarios. The design proposal integrates traditional tools and technologies with the new possibilities offered by Key Enabling Technologies prefiguring a replicable model for a resilient, inclusive and lowenvironmental impact city

Clinical and imaging findings in enteropathic spondyloarthritis with special emphasize in diagnostic delay: a cross-sectional study

Background: Enteropathic spondyloarthritides (eSpAs) are chronic inflammatory joint diseases associated with inflammatory bowel disease (IBD). Limited data are available on the prevalence since arthritis in IBD patients may be underestimated because medications may hide disease activity with a possible diagnostic delay. Objectives: We aimed to evaluate diagnostic delay in eSpA and explore associated demographic, clinical, and radiographic characteristics. Design: Single-centre cross-sectional study conducted on consecutive out-patients referred to the combined Gi-Rhe clinic (November 2018–October 2019). Methods: We analysed eSpA patients for diagnostic delay, disease activity, inflammatory markers, conventional radiography (CR) and magnetic resonance images (MRI) of sacroiliac joints/spine. Results: A total of 190 eSpA patients [118 peripheral SpA, 72 axial (Ax) SpA including 44 non-radiographic (nr)-axSpA] were enrolled. axSpA patients had a higher prevalence of men sex, HLA-B27 positivity, uveitis and pancolitis compared with peripheral eSpA. Median diagnostic delay in eSpA was 48 months (IQR 6–77) with no difference between axial and peripheral patients. Radiographic-axial SpA (r-axSpA) patients displayed a higher diagnostic delay compared with nr-axSpA (median/IQR 36/17–129 versus 31/10–57 months, p  = 0.03) and were older, with longer disease duration, low education status and high rate of employment than patients with nr-axSpA. r-axSpA patients with sclerosis, syndesmophytes and bridge at CR had higher diagnostic delay than those without lesions. Men showed higher prevalence of spine damage lesions than women as sclerosis, squaring, syndesmophytes and bridges. Longer disease duration was detected in patients with radiographic damage as bridge and sacroiliitis grade 3. On MRI, sacroiliac bone oedema was associated with reduced diagnostic delay, whereas bone erosions were associated with higher diagnostic delay compared with that in patients without these lesions. Patients with psoriasis displayed a higher diagnostic delay compared to those without skin involvement. Conclusion: Diagnostic delay was higher in r-axSpA compared with nr-axSpA despite the same treatment. Demographic, clinical features and radiological lesions were associated with diagnostic delay

The Challenging Differentiation of Psoriatic Arthritis from Other Arthropathies and Nonspecific Arthralgias in Patients with Psoriasis: Results of a Cross-Sectional Rheumatologic Assessment of a Large Dermatologic Cohort

Aiming to identify the potential challenges in the classification of musculoskeletal manifestations in patients with psoriasis (PsO), this study analyzed the outcomes of a cross-sectional rheumatologic assessment of 1057 PsO patients. In total, 209 had a previous diagnosis of psoriatic arthritis (PsA). Out of the remaining 848 subjects, 293 (35%) were classified as suspected PsA cases according to the rheumatologist’s judgment and/or Early PsA Screening Questionnaire score (EARP) ≥ 3. However, only 14% received a PsA diagnosis, 49% had a PsA-alternative diagnosis, and the remaining 37% had nonspecific arthralgias. Most of the newly diagnosed PsA patients had a symptoms duration ≥1 year (72%) and moderate disease activity (55%) with active oligoarthritis (85%), dactylitis, or enthesitis (35%) as the most frequent clinical pattern. The most frequent PsA-alternative diagnoses were osteoarthritis and fibromyalgia (44% and 41%). The only factors with significant (p < 0.05) utility in discriminating PsA from other diseases and nonspecific arthralgias were young age and EARP score with a history of morning stiffness, swollen joints, or dactylitis. These results demonstrated a high prevalence of suspected musculoskeletal symptoms in PsO patients, with, however, only a small proportion due to PsA. Close collaboration between the dermatologist and rheumatologist plays a crucial role in the differential diagnosis of PsA, as well as in monitoring nonspecific arthralgias for the potential transition to overt PsA