Assessment of the availability and effectiveness of environmental education through the Eco-Schools Programme at Umzinyathi District schools

(a) Background of the study The study was conducted at Umzinyathi District schools. Umzinyathi District comprises of four circuits, i.e. Umvoti, Nqutu, Msinga and Endumeni. The study intended to find out if EE education is available and effective enough through Eco-Schools Programme at Umzinyathi District Schools. Each circuit was represented by three schools. One school was the school that was registered with Eco-Schools Programme and have a green flag status, the second school was the school that was registered with Eco-Schools Programme and working towards getting the green flag status and the third school was the school that was not registered with the Eco-Schools Programme. (b) Methodology Qualitative, explorative research was conducted in order to determine the availability and effectiveness of Eco-Schools Programme at Umzinyathi District Schools. Data collection was done using different types of interviews for different types of participants, i.e. educators, learners, members of the School Governing Bodies, officials of the DoE, DAEA as well as of the local municipalities. Site visits to the Eco-Schools was also used to collect data. When collecting data, a tape recorder was used. The interviews were conducted in both isiZulu and English and translated to English by the researcher. (c) Results and findings The study proved that Eco-Schools Programme is the necessary tool in bringing about the change in teaching about protecting and caring about the environment. The study also discovered that at the Umzinyathi District is not available and effective enough. Another thing the study discovered is that, there is another programme that is run by the DAEA, which is called NEEP (National Environmental Education Programme). The study also finds out that some of the Eco-Schools are also registered with this programme. (d) Recommendations It was recommended that the Eco-Schools Programme be compulsory to all the schools of Umzinyathi District where the study was based. Another recommendation was that the Department of Education appoint some people within the department to work full time with the DAEA in implementing, monitoring, supporting and assessing the progress of the programme in the district.Environmental SciencesM. Ed. (Environmental Education

Gendered Infrastructural Citizenship: Shared Sanitation Facilities in Quarry Road West Informal Settlement, Durban, South Africa

One significant component of the South African citizenship narrative is centred around the right to basic services and corresponding elements, including dignity and a healthy living environment. This paper employs the concept of infrastructural citizenship, which draws on both infrastructure and citizenship discourses to explore how participants experience and challenge public infrastructure and as such engage with questions surrounding citizenship on an everyday basis (Lemanski, 2019a). Adopting a gendered approach, this paper draws on the empirical case of Quarry Road West, an informal settlement located in Durban, and uses a qualitative methodology. Residents have access to Community Ablution Blocks, free shared sanitation facilities provided by the eThekwini Municipality. This paper argues that restricted access to the facilities undermines perceptions of privacy and health and negatively impacts women individually and in the community. Furthermore, this paper evaluates civic responses to inadequate infrastructure in the form of participation, protest and state-directed actions. As such, it examines how women-state relationships are embedded in public infrastructure, and limitations in regards to infrastructure shape interactions and engagements with the state, their experiences of citizenship, actualisation of rights and identities

New housing/new crime? Changes in safety, governance and everyday incivilities for residents relocated from informal to formal housing at Hammond's Farm, eThekwini

New state-subsidised ‘RDP’ housing in South Africa aims to provide former informally-housed residents with a better quality of life, stronger community and decreased levels of crime. Despite the state’s ambitions, this process is highly contradictory, increases in safety occurring alongside rising incivilities and tensions. This paper contributes to an emerging set of debates on the socio-political outcomes of state-led housing interventions in the global South, through an illustration of the limitations of efforts to produce ‘safe neighbourhoods’ in contexts of high unemployment alongside high levels of violence. The conceptual framing of ‘Southern Criminology’ (Carrington et al, 2015), centres the significance of histories of colonial and post-colonial violence, inequality, hybrid governance and justice practices, as well as informal living, and is employed to analyse recently housed residents’ experiences of crime and safety in South Africa, in a north eThekwini settlement, Hammond’s Farm. Recognising these ‘Southern’ factors, the paper argues that movement into new formal housing, is typified by significant material changes at the home and neighbourhood scale which foster privacy and safety, formalised governance practices and (partial) improvements in policing services. These occur in conjunction with access to new leisure activities including alcohol consumption and ‘township life’ which alongside ongoing poverty foster urban incivilities. A ‘Southern Criminology’ perspective frames concluding questions about the nature of crime in contexts of urban change, which are persistently shaped by inequality and wider historical and structural factors, challenging the state’s aspirations to achieve crime reduction through housing

A retrospective 5-year review of rubella in South Africa prior to the introduction of a rubella-containing vaccine

South Africa has yet to introduce a rubella-containing vaccine (RCV) into its Expanded Programme on Immunisation (EPI). Here we evaluated the incidence of laboratory-confirmed rubella and congenital rubella syndrome (CRS) cases over the years 2015 to 2019, to document the epidemiology of rubella and CRS within South Africa prior to a RCV introduction. This retrospective study evaluated the number of laboratory-confirmed rubella cases reported through the national febrile rash surveillance system. A positive test for rubella immunoglobulin M (IgM) antibodies was considered a confirmed rubella case. For CRS cases, we reported laboratory-confirmed CRS cases collected from 28 sentinel-sites from all nine provinces of South Africa. From 2015–2019, 19 773 serum samples were tested for rubella IgM antibodies, 6 643 (33.6%) were confirmed rubella cases. Rubella was seasonal, with peaks in spring (September to November). Case numbers were similar between males (n = 3 239; 50.1%) and females (n = 3 232; 49.9%). The highest burden of cases occurred in 2017 (n = 2 526; 38%). The median age was 5 years (IQR: 3–7 years). Importantly, of females with rubella, 5.0% (161 of 3 232) of the cases were among women of reproductive age (15–44 years). A total of 62 CRS cases were reported, the mortality rate was 12.9% (n = 8), and the most common birth defect was congenital heart disease. In conclusion, rubella is endemic in South Africa. Children below the age of 10 years were the most affected, however, rubella was also reported among women of reproductive age. The baseline data represented here provides insight into the burden of rubella and CRS in South Africa prior to the introduction of a RCV, and can enable planning of RCV introduction into the South African EPI.The National Institute for Communicable Diseases, a division of the National Health Laboratory Service, South Africa.http://www.plosone.orgdm2022School of Health Systems and Public Health (SHSPH

Dolutegravir twice-daily dosing in children with HIV-associated tuberculosis: a pharmacokinetic and safety study within the open-label, multicentre, randomised, non-inferiority ODYSSEY trial

Background: Children with HIV-associated tuberculosis (TB) have few antiretroviral therapy (ART) options. We aimed to evaluate the safety and pharmacokinetics of dolutegravir twice-daily dosing in children receiving rifampicin for HIV-associated TB. Methods: We nested a two-period, fixed-order pharmacokinetic substudy within the open-label, multicentre, randomised, controlled, non-inferiority ODYSSEY trial at research centres in South Africa, Uganda, and Zimbabwe. Children (aged 4 weeks to <18 years) with HIV-associated TB who were receiving rifampicin and twice-daily dolutegravir were eligible for inclusion. We did a 12-h pharmacokinetic profile on rifampicin and twice-daily dolutegravir and a 24-h profile on once-daily dolutegravir. Geometric mean ratios for trough plasma concentration (Ctrough), area under the plasma concentration time curve from 0 h to 24 h after dosing (AUC0–24 h), and maximum plasma concentration (Cmax) were used to compare dolutegravir concentrations between substudy days. We assessed rifampicin Cmax on the first substudy day. All children within ODYSSEY with HIV-associated TB who received rifampicin and twice-daily dolutegravir were included in the safety analysis. We described adverse events reported from starting twice-daily dolutegravir to 30 days after returning to once-daily dolutegravir. This trial is registered with ClinicalTrials.gov (NCT02259127), EudraCT (2014–002632-14), and the ISRCTN registry (ISRCTN91737921). Findings: Between Sept 20, 2016, and June 28, 2021, 37 children with HIV-associated TB (median age 11·9 years [range 0·4–17·6], 19 [51%] were female and 18 [49%] were male, 36 [97%] in Africa and one [3%] in Thailand) received rifampicin with twice-daily dolutegravir and were included in the safety analysis. 20 (54%) of 37 children enrolled in the pharmacokinetic substudy, 14 of whom contributed at least one evaluable pharmacokinetic curve for dolutegravir, including 12 who had within-participant comparisons. Geometric mean ratios for rifampicin and twice-daily dolutegravir versus once-daily dolutegravir were 1·51 (90% CI 1·08–2·11) for Ctrough, 1·23 (0·99–1·53) for AUC0–24 h, and 0·94 (0·76–1·16) for Cmax. Individual dolutegravir Ctrough concentrations were higher than the 90% effective concentration (ie, 0·32 mg/L) in all children receiving rifampicin and twice-daily dolutegravir. Of 18 children with evaluable rifampicin concentrations, 15 (83%) had a Cmax of less than the optimal target concentration of 8 mg/L. Rifampicin geometric mean Cmax was 5·1 mg/L (coefficient of variation 71%). During a median follow-up of 31 weeks (IQR 30–40), 15 grade 3 or higher adverse events occurred among 11 (30%) of 37 children, ten serious adverse events occurred among eight (22%) children, including two deaths (one tuberculosis-related death, one death due to traumatic injury); no adverse events, including deaths, were considered related to dolutegravir. Interpretation: Twice-daily dolutegravir was shown to be safe and sufficient to overcome the rifampicin enzyme-inducing effect in children, and could provide a practical ART option for children with HIV-associated TB

Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial

BACKGROUND: Cohort studies in adults with HIV showed that dolutegravir was associated with neuropsychiatric adverse events and sleep problems, yet data are scarce in children and adolescents. We aimed to evaluate neuropsychiatric manifestations in children and adolescents treated with dolutegravir-based treatment versus alternative antiretroviral therapy. METHODS: This is a secondary analysis of ODYSSEY, an open-label, multicentre, randomised, non-inferiority trial, in which adolescents and children initiating first-line or second-line antiretroviral therapy were randomly assigned 1:1 to dolutegravir-based treatment or standard-of-care treatment. We assessed neuropsychiatric adverse events (reported by clinicians) and responses to the mood and sleep questionnaires (reported by the participant or their carer) in both groups. We compared the proportions of patients with neuropsychiatric adverse events (neurological, psychiatric, and total), time to first neuropsychiatric adverse event, and participant-reported responses to questionnaires capturing issues with mood, suicidal thoughts, and sleep problems. FINDINGS: Between Sept 20, 2016, and June 22, 2018, 707 participants were enrolled, of whom 345 (49%) were female and 362 (51%) were male, and 623 (88%) were Black-African. Of 707 participants, 350 (50%) were randomly assigned to dolutegravir-based antiretroviral therapy and 357 (50%) to non-dolutegravir-based standard-of-care. 311 (44%) of 707 participants started first-line antiretroviral therapy (ODYSSEY-A; 145 [92%] of 157 participants had efavirenz-based therapy in the standard-of-care group), and 396 (56%) of 707 started second-line therapy (ODYSSEY-B; 195 [98%] of 200 had protease inhibitor-based therapy in the standard-of-care group). During follow-up (median 142 weeks, IQR 124–159), 23 participants had 31 neuropsychiatric adverse events (15 in the dolutegravir group and eight in the standard-of-care group; difference in proportion of participants with ≥1 event p=0·13). 11 participants had one or more neurological events (six and five; p=0·74) and 14 participants had one or more psychiatric events (ten and four; p=0·097). Among 14 participants with psychiatric events, eight participants in the dolutegravir group and four in standard-of-care group had suicidal ideation or behaviour. More participants in the dolutegravir group than the standard-of-care group reported symptoms of self-harm (eight vs one; p=0·025), life not worth living (17 vs five; p=0·0091), or suicidal thoughts (13 vs none; p=0·0006) at one or more follow-up visits. Most reports were transient. There were no differences by treatment group in low mood or feeling sad, problems concentrating, feeling worried or feeling angry or aggressive, sleep problems, or sleep quality. INTERPRETATION: The numbers of neuropsychiatric adverse events and reported neuropsychiatric symptoms were low. However, numerically more participants had psychiatric events and reported suicidality ideation in the dolutegravir group than the standard-of-care group. These differences should be interpreted with caution in an open-label trial. Clinicians and policy makers should consider including suicidality screening of children or adolescents receiving dolutegravir

Social differentiation, boredom and crime within the peripheries

No abstract available

Social constructions of environmental services in a rapidly densifying peri-urban area under dual governance in Durban, South Africa

Background: Biodiversity plays a critical role in improving the quality of life and resilience of poor urban communities in Durban. Objectives: However, the rapid densification that is taking place in the ‘rural periphery’ of the city is impacting significantly on the integrity of ecosystems, which provide valuable ecosystem services. It is also changing the relations between people and the environment. Mzinyathi and eSkebheni, in the north-west of Durban, are peri-urban areas located on Ingonyama Trust land and hence they are governed by both the traditional authority and the eThekwini Municipality. The settlement pattern is changing rapidly here as middle and upper income residents move into the area, changing the way of life from being rural and ‘traditional’ to urban and ‘modern’. Method: This paper focused on the nexus of rapid urban growth, dual governance systems, biodiversity loss and cultural change in these two areas. It adopted a qualitative methodology and social constructivist approach. Data on the value of environmental services in the area was collected through interviewing the traditional authority, provincial and municipal planners and environmentalists, and household members. Results: The paper revealed that environmental services are constructed in multiple ways within a particular socio-historical and political context, that they have value to peri-urban communities, and that their function and use is changing as a result of the ‘modernisation’ of the area. The impact of the dual governance system and traditional land allocation process on environmental services is significant. This has implications for long term sustainability, for the quality of life of peri-urban residents and for planning and urban governance