Clinical signs and symptoms during first episode of clinical malaria.

<p>Note: There were no significant difference between the two cohorts for any of the clinical parameters studied.</p

Baseline characteristics of the study population.

*<p>matched by design.</p><p>A = from screening data.</p><p>B = from baseline data.</p><p>C = at either screening or baseline.</p><p>NA, not applicable.</p

Incidence of clinical malaria.

<p>The bars represent the number of FIL+ (black bars) and FIL− (gray bars) subjects who experienced 0, 1, 2 or 3 episodes of clinical malaria during the first transmission season.</p

Changes in filarial status over the course of the study.

<p>Changes in filarial status over the course of the study.</p

Negative correlation between serum levels of IP-10 during acute malaria and Hgb levels at the peak of malaria transmission.

<p>The symbols represent the values for individual study subjects.</p

Plasma cytokine and chemokine levels at the time of acute malaria.

<p>The symbols represent individual values for FIL+ (black circles) and FIL− (gray circles) subjects. The horizontal lines represent the GM values for the groups.</p

Study flowchart.

<p>Study flowchart.</p

Time to first episode of clinical malaria.

<p>The cumulative % of FIL+ (black line) and FIL− (gray line) subjects who had experienced at least one episode of malaria is shown for each week of the first transmission season (estimated by Kaplan-Meier method to account for subjects who withdrew from the study).</p