Funnel plots presenting prognostic value of ABCB1 for OS, PFS and TR.

<p>OS = overall survival; PFS = progression free survival; TR = total response rate. A, funnel plots showing the distribution of effect size and prevision of individual study estimate when evaluating the summary HR for OS. Egger’s test: <i>P</i> = 0.078. B, funnel plots showing the distribution of effect size and prevision of individual study estimate when evaluating the summary HR for PFS. Egger’s test: <i>P</i> = 0.146. C, funnel plots showing the distribution of effect size and prevision of individual study estimate when evaluating the summary RR for TR. Egger’s test: <i>P</i> = 0.019.</p

Forest plots of subgroup meta-analysis presenting RRs of EOC TR for high ABCB1 expression.

<p>RR = risk ratio; EOC = epithelial ovarian cancer; TR = total response rate.</p

Characteristics of studies that identify ABCB1 protein (p-gp) expression in epithelial ovarian cancer.

<p>Characteristics of studies that identify ABCB1 protein (p-gp) expression in epithelial ovarian cancer.</p

Forest plots presenting RRs of EOC TR for high ABCB1 expression.

<p>RR = risk ratio; EOC = epithelial ovarian cancer; TR = total response rate.</p

Characteristics of studies that identify ABCB1 mRNA expression and <i>ABCB1</i> gene variants in epithelial ovarian cancer.

<p>Characteristics of studies that identify ABCB1 mRNA expression and <i>ABCB1</i> gene variants in epithelial ovarian cancer.</p

Forest plots of subgroup meta-analysis presenting HRs of EOC OS for high ABCB1 expression.

<p>HR = hazard ratio; EOC = epithelial ovarian cancer; OS = overall survival.</p

Forest plots of HRs of EOC OS for high ABCB1 expression stratified by geographical region.

<p>HR = hazard ratio; EOC = epithelial ovarian cancer; OS = overall survival.</p

Forest plots presenting HRs of EOC PFS for high ABCB1 expression, adjusted results and <i>ABCB1</i> gene variants.

<p>HR = hazard ratio; EOC = epithelial ovarian cancer; PFS = progression free survival.</p

Flow chart of literature search and selection.

<p>Flow chart of literature search and selection.</p

Forest plots presenting HRs of EOC OS for high ABCB1 expression, adjusted results and <i>ABCB1</i> gene variants.

<p>HR = hazard ratio; EOC = epithelial ovarian cancer; OS = overall survival.</p