3 research outputs found
Captured video of augmented scene, when the camera changes focus
Captured video of augmented scene, when the camera changes focu
Plasma Lipidomics Investigation of Hemodialysis Effects by Using Liquid Chromatography–Mass Spectrometry
Chronic
kidney disease (CKD) has been a global health problem that
has a great possibility of being developed into uremia in the end.
Hemodialysis (HD) is the most commonly used strategy for treating
uremic patients; however, the patients still have a high risk of suffering
various complications. It is well recognized that lipid disorder usually
occurs in maintenance HD patients. To systemically study the effects
of HD on lipid metabolism associated with uremia, we employed an ultraperformance
liquid chromatography–quadrupole-time-of-flight mass spectrometry
(UPLC-Q-TOF/MS)-based lipidomics method. A total of 87 human plasma
samples from patients with prehemodialysis (pre-HD)/posthemodialysis
(post-HD) treatment and the healthy controls were enrolled in the
study. As compared with pre-HD patients, many plasma lipids showed
significant changes (<i>p</i> < 0.05) in patients receiving
HD therapy. Specifically, sum of free fatty acids (FFA) as well as
saturated FFA and eicosanoids and sums of lyso-phosphatidylinositols
and lyso-phosphatidylethanolamines, FFA 16:1/FFA 16:0, and FFA 18:1/FFA
18:0 were obviously higher in the pre-HD group than in the controls
while they were significantly lower in patients after HD. These results indicated that UPLC-Q-TOF/MS-based lipidomics is a
promising approach to investigate lipid alterations in relation to
uremia and it is helpful to understand complex complications involved
in HD patients
Visualization 1: Highly photorefractive hybrid liquid crystal device for a video-rate holographic display
Visualization 1 blue running horse Originally published in Optics Express on 18 April 2016 (oe-24-8-8824