3 research outputs found
One-Pot Tandem Approach to Functionalized 3鈥慔ydroxy-2-furanyl-acrylamides
A novel
one-pot tandem process involving Knoevenagel condensation,
Michael addition, selective amidation, and Paal鈥揔norr cyclization
to diverse functionalized 3-hydroxy-2-furanyl-acrylamides from simple
2-oxoaldehydes and aroylacetonitriles was presented. Attempts were
also made to expand the scope of the reaction to different 2-heteroarylfurans.
The packing diagram of the molecules viewed down along the 伪-axis
of the unit cell showed a characteristic intramolecular classical
O鈥揌路路路O hydrogen bond between hydroxyl and carbonyl
O atoms leading to self-associated (<i>Z</i>)-2-furanyl-acrylamides
One-Pot Tandem Approach to Functionalized 3鈥慔ydroxy-2-furanyl-acrylamides
A novel
one-pot tandem process involving Knoevenagel condensation,
Michael addition, selective amidation, and Paal鈥揔norr cyclization
to diverse functionalized 3-hydroxy-2-furanyl-acrylamides from simple
2-oxoaldehydes and aroylacetonitriles was presented. Attempts were
also made to expand the scope of the reaction to different 2-heteroarylfurans.
The packing diagram of the molecules viewed down along the 伪-axis
of the unit cell showed a characteristic intramolecular classical
O鈥揌路路路O hydrogen bond between hydroxyl and carbonyl
O atoms leading to self-associated (<i>Z</i>)-2-furanyl-acrylamides
One-Pot Tandem Approach to Functionalized 3鈥慔ydroxy-2-furanyl-acrylamides
A novel
one-pot tandem process involving Knoevenagel condensation,
Michael addition, selective amidation, and Paal鈥揔norr cyclization
to diverse functionalized 3-hydroxy-2-furanyl-acrylamides from simple
2-oxoaldehydes and aroylacetonitriles was presented. Attempts were
also made to expand the scope of the reaction to different 2-heteroarylfurans.
The packing diagram of the molecules viewed down along the 伪-axis
of the unit cell showed a characteristic intramolecular classical
O鈥揌路路路O hydrogen bond between hydroxyl and carbonyl
O atoms leading to self-associated (<i>Z</i>)-2-furanyl-acrylamides