DataSheet1_Effect of myopia and astigmatism deepening on the corneal biomechanical parameter stress-strain index in individuals of Chinese ethnicity.xlsx

Purpose: To investigate the differences in corneal biomechanical parameter stress–strain index (SSI) among different degrees of myopic eyes in Chinese individuals and to analyze the relevant factors of the SSI.Methods: This study analyzed the right eyes of 240 participants (240 eyes) aged 18–34 years. The participants were divided into low-, moderate-, high-, and ultra-high myopia groups according to their spherical equivalent (SE), with 60 eyes included in each group. Spherical, cylinder, and SE were measured via automatically integrated optometry. Intraocular pressure (IOP) was measured using a non-contact tonometer. AL was measured using an IOLMaster device. Corneal curvature and central corneal thickness (CCT) were measured using a Pentacam. SSI and biomechanical corrected IOP (bIOP) were measured via corneal visualization Scheimpflug technology (Corvis ST). The statistical analyses included one-sample Kolmogorov–Smirnov tests and normal distribution histogram methods, Levene variance homogeneity tests, Pearson’s correlation analyses, multiple linear stepwise regression analyses, one-way ANOVA, and LSD t-tests.Results: The mean (±SD) age of the 240 participants was (24.97 ± 4.16) years. The SSI was positively correlated with spherical, cylinder, SE, CCT, IOP, and bIOP and negatively correlated with K1 and AL (r = 0.475, 0.371, 0.497, 0.169, 0.291, 0.144, −0.154, and −0.464, respectively; all p 0.05). Multiple linear regression analysis performed with SSI as the dependent variable, and spherical, cylinder, K1, CCT, and IOP as independent variables produced the following regression equation: SSI = 0.989 + 0.017 spherical + 0.042 cylinder +0.018 IOP (R2 = 0.402, F = 31.518, p 0.05).Conclusion: SSI decreased with increasing myopia and astigmatism in the Chinese participants. The SSI was significantly lower in high and ultra-high myopia, especially ultra-high myopia. These findings indicate that increased corneal elasticity may be related to the pathogenesis of high and ultra-high myopia.</p

DataSheet2_Effect of myopia and astigmatism deepening on the corneal biomechanical parameter stress-strain index in individuals of Chinese ethnicity.xlsx

Purpose: To investigate the differences in corneal biomechanical parameter stress–strain index (SSI) among different degrees of myopic eyes in Chinese individuals and to analyze the relevant factors of the SSI.Methods: This study analyzed the right eyes of 240 participants (240 eyes) aged 18–34 years. The participants were divided into low-, moderate-, high-, and ultra-high myopia groups according to their spherical equivalent (SE), with 60 eyes included in each group. Spherical, cylinder, and SE were measured via automatically integrated optometry. Intraocular pressure (IOP) was measured using a non-contact tonometer. AL was measured using an IOLMaster device. Corneal curvature and central corneal thickness (CCT) were measured using a Pentacam. SSI and biomechanical corrected IOP (bIOP) were measured via corneal visualization Scheimpflug technology (Corvis ST). The statistical analyses included one-sample Kolmogorov–Smirnov tests and normal distribution histogram methods, Levene variance homogeneity tests, Pearson’s correlation analyses, multiple linear stepwise regression analyses, one-way ANOVA, and LSD t-tests.Results: The mean (±SD) age of the 240 participants was (24.97 ± 4.16) years. The SSI was positively correlated with spherical, cylinder, SE, CCT, IOP, and bIOP and negatively correlated with K1 and AL (r = 0.475, 0.371, 0.497, 0.169, 0.291, 0.144, −0.154, and −0.464, respectively; all p 0.05). Multiple linear regression analysis performed with SSI as the dependent variable, and spherical, cylinder, K1, CCT, and IOP as independent variables produced the following regression equation: SSI = 0.989 + 0.017 spherical + 0.042 cylinder +0.018 IOP (R2 = 0.402, F = 31.518, p 0.05).Conclusion: SSI decreased with increasing myopia and astigmatism in the Chinese participants. The SSI was significantly lower in high and ultra-high myopia, especially ultra-high myopia. These findings indicate that increased corneal elasticity may be related to the pathogenesis of high and ultra-high myopia.</p

Table_1_TikTok and adolescent vision health: Content and information quality assessment of the top short videos related to myopia.DOCX

BackgroundDespite the increasing recognition of the public health value of social media platforms, TikTok short videos focusing on adolescent vision health have not received much attention. We aimed to evaluate the content, sources, and information quality of myopia-related videos on TikTok.MethodsThe top 200 most-liked myopia-related videos on the Chinese version of TikTok were queried and screened on March 12, 2022. The descriptive characteristics, contents, and sources of the selected 168 videos were obtained, and their overall quality, reliability, understandability, and actionability were assessed using the validated scoring instruments DISCERN and PEMAT-A/V.ResultsMedical professionals were the main source (45.8%, 77/168) of videos. Misinformation (10.1%, 17/168) was mainly attributable to for-profit organizations (20%, 3/15) and individual non-medical users (31.3%, 10/32). However, their videos enjoyed the highest numbers of “likes,” “comments,” and “shares” (P ConclusionConsidering the moderate-to-poor reliability and variable quality across video sources, the substantial myopia-related content on TikTok should be treated with caution. Nevertheless, TikTok videos may serve as a surrogate or supplement for information dissemination if providers can ensure more comprehensive and accurate content.</p

The comparison of mean and SD among different populations.

a<p>S.M.Skevington, M.Lotfy,K.A.O'Connell.(2004)The World Health Organization's WHOQOL-BREF quality of life assessment: sychometric properties and results of the international field trial A Report from the WHOQOL Group.Quality of life research,13:299–310.</p>b<p>The WHOQOL Group. The world health organisation quality of life assessment (WHOQOL): position paper from the World Health Organisation. Social Science and Medicine, 1995, 41, 1403–1409.</p>c<p>The WHOQOL Group. The world health organisation quality of life assessment (WHOQOL): development and general psychometric properties. Soc Sci Med, 1998, 46: 1569–1585.</p

Results of multiple stepwise regression analysis for QOL.

<p>Reference group: ^aCompared with ≤200 <i>p</i><0.05; ^bCompared with 0 year <i>p</i><0.05;</p>c<p>Compared with farmer <i>p</i><0.05; ^dCompared with <40 <i>p</i><0.05; ^eCompared with no reported STD symptom <i>p</i><0.05; ^fCompared with no migrate worker <i>p</i><0.05.</p

Demographic Information, mean scores and standard deviations of four domains of Chinese WHOQOL-BREF (n = 1009).

a<p>t-test, <i>p</i><0.05; ^b one-way ANOVA p<0.05; ^cFirst-line scheme: AZT/D4T+3TC + EFV/NVP, alternative scheme: AZT/D4T+3TC + IDV, DDI+D4T + EFV/NVP or AZT + DDI + EFV/NVP. As of the date of survey, patients undergoing ART who has ever changed from the above first-line scheme to alternative scheme were classified as ART regimen switched.</p