The Experiences of Taiwanese Women Caregiving for Parents-in-Law

Using grounded theory, a semi-structured in-depth interview was conducted to explore the experiences of Taiwanese women who were caregivers for their parents-in-law. Thirty-one Taiwanese women aged 23 to 58 participated in this study. Just Doing was identified as the core category to indicate the caregivers\u27 striving process once they committed to their in-laws\u27 care. Recognizing Duty, Experiencing Trials, and Responding to Caregiving were subcategories and reflected how a caregiver perceived her role, how she was affected by caregiving tasks, and what responses she had to the caregiving situation. The findings also suggested that caregiving behaviors were influenced by cultural expectations when the parent-in-law was ill. Being Called, a condition in this study, indicated that caregiving tasks were started when the caregiver recognized providing care was her duty. Caring For reflected the context for providing daily comfort, keeping watch, as well as seeking assistance if needed. The category of Holding Up involved the ability to persevere in providing care and was influenced by the depth of family relationships, their appreciation and degree of reinforcement. The extent of the difficulties and the resources for care also affected the ability to continue caring. Additionally, the strategy of Keeping Harmony, was adopted by caregivers to comfort themselves and cope with their caregiving difficulties. This category reflected Taiwanese women\u27s fatalism and optimism in meeting the daily care needs of a parent-in-law. Maintaining Filial Pity was identified as a consequence of a caregiver\u27s experience in fulfilling her duty. As a daughter-in-law, she was able to establish an inner peace or serenity. If this was not possible, she continued to have inner conflict and perceived her life as one of sacrifice. This story of Taiwanese women caregivers\u27 experiences may be beneficial in facilitating the development of a comprehensive policy for long-term care. These women\u27s voices will be helpful in forming the basis for nursing intervention strategies for individual and family care. Recommendations for future research focus on cultural determinants of caregiving roles and coping strategies

Hunting for Heavy Majorana Neutrinos with Lepton Number Violating Signatures at LHC

The neutrinophilic two-Higgs-doublet model ($\nu$2HDM) provides a natural way to generate tiny neutrino mass from interactions with the new doublet scalar $\Phi_\nu$ ($H^\pm,~H,~A$) and singlet neutrinos $N_R$ of TeV scale. In this paper, we perform detailed simulations for the lepton number violating (LNV) signatures at LHC arising from cascade decays of the new scalars and neutrinos with the mass order $m_{N_R}<m_{\Phi_\nu}$. Under constraints from lepton flavor violating processes and direct collider searches, their decay properties are explored and lead to three types of LNV signatures: $2\ell^\pm 4j+\cancel{E}_T$, $3\ell^\pm 4j+\cancel{E}_T$, and $3\ell^\pm\ell^\mp 4j$. We find that the same-sign trilepton signature $3\ell^\pm4j+\cancel{E}_T$ is quite unique and is the most promising discovery channel at the high-luminosity LHC. Our analysis also yields the $95\%$ C.L. exclusion limits in the plane of the $\Phi_\nu$ and $N_R$ masses at 13 (14) TeV LHC with an integrated luminosity of 100~(3000)/fb.Comment: 31 pages, 17 figures, 6 tables; v2: added a few refs and updated one ref, without other change

Threshold Effects in the Decay of Heavy b' and t' Quarks

A sequential fourth generation is still viable, but the t' and b' quarks are constrained to be not too far apart in mass. The t'{\to}bW and b'{\to}tW decay channels are still being pursued at the Tevatron, which would soon be surpassed by the LHC. We use a convolution method with up to five-body final state to study t' and b' decays. We show how the two decay branches for m_{b'} below the tW threshold, b'{\to}tW^* and t^*W, merge with b'{\to}tW above the threshold. We then consider the heavy-to-heavy transitions b'{\to}t^{\prime(*)}W^{(*)} (or t'{\to}b^{\prime(*)}W^{(*)}), as they are not suppressed by quark mixing. We find that, because of the threshold sensitivity of the branching fraction of t'{\to}b'W^* (or b'{\to}t'W^*), it is possible to measure the strength of the CKM mixing element V_{t'b} (or V_{tb'}), especially when it is rather small. We urge the experiments to pursue and separate the t'{\to}b'W^* (or b'{\to}t'W^*) decay in their search program

Demonstration of chronometric leveling using transportable optical clocks beyond laser coherence limit

Optical clock network requires the establishment of optical frequency transmission link between multiple optical clocks, utilizing narrow linewidth lasers. Despite achieving link noise levels of 10${^{-20}}$, the final accuracy is limited by the phase noise of the clock laser. Correlation spectroscopy is developed to transmit frequency information between two optical clocks directly, enabling optical clock comparison beyond the phase noise limit of clock lasers, and significantly enhancing the measurement accuracy or shorten the measurement time. In this letter, two compact transportable ${^{40}}$Ca${^+}$ clocks are employed to accomplish the correlation spectroscopy comparison, demonstrating an 10 cm level measurement accuracy of chronometric leveling using a mediocre clock laser with linewidth of 200 Hz. The relative frequency instability reaches $6.0\times10{^{-15}}/\sqrt{\tau/s}$, which is about 20 times better than the result with Rabi spectroscopy using the same clock laser. This research greatly reduces the harsh requirements on the performance of the clock laser, so that an ordinary stable-laser can also be employed in the construction of optical clock network, which is essential for the field applications, especially for the chronometric leveling

A Survey on LLM-generated Text Detection: Necessity, Methods, and Future Directions

The powerful ability to understand, follow, and generate complex language emerging from large language models (LLMs) makes LLM-generated text flood many areas of our daily lives at an incredible speed and is widely accepted by humans. As LLMs continue to expand, there is an imperative need to develop detectors that can detect LLM-generated text. This is crucial to mitigate potential misuse of LLMs and safeguard realms like artistic expression and social networks from harmful influence of LLM-generated content. The LLM-generated text detection aims to discern if a piece of text was produced by an LLM, which is essentially a binary classification task. The detector techniques have witnessed notable advancements recently, propelled by innovations in watermarking techniques, zero-shot methods, fine-turning LMs methods, adversarial learning methods, LLMs as detectors, and human-assisted methods. In this survey, we collate recent research breakthroughs in this area and underscore the pressing need to bolster detector research. We also delve into prevalent datasets, elucidating their limitations and developmental requirements. Furthermore, we analyze various LLM-generated text detection paradigms, shedding light on challenges like out-of-distribution problems, potential attacks, and data ambiguity. Conclusively, we highlight interesting directions for future research in LLM-generated text detection to advance the implementation of responsible artificial intelligence (AI). Our aim with this survey is to provide a clear and comprehensive introduction for newcomers while also offering seasoned researchers a valuable update in the field of LLM-generated text detection. The useful resources are publicly available at: https://github.com/NLP2CT/LLM-generated-Text-Detection

Mitochondrion-Permeable Antioxidants to Treat ROS-Burst-Mediated Acute Diseases

Reactive oxygen species (ROS) play a crucial role in the inflammatory response and cytokine outbreak, such as during virus infections, diabetes, cancer, cardiovascular diseases, and neurodegenerative diseases. Therefore, antioxidant is an important medicine to ROS-related diseases. For example, ascorbic acid (vitamin C, VC) was suggested as the candidate antioxidant to treat multiple diseases. However, long-term use of high-dose VC causes many side effects. In this review, we compare and analyze all kinds of mitochondrion-permeable antioxidants, including edaravone, idebenone, α-Lipoic acid, carotenoids, vitamin E, and coenzyme Q10, and mitochondria-targeted antioxidants MitoQ and SkQ and propose astaxanthin (a special carotenoid) to be the best antioxidant for ROS-burst-mediated acute diseases, like avian influenza infection and ischemia-reperfusion. Nevertheless, astaxanthins are so unstable that most of them are inactivated after oral administration. Therefore, astaxanthin injection is suggested hypothetically. The drawbacks of the antioxidants are also reviewed, which limit the use of antioxidants as coadjuvants in the treatment of ROS-associated disorders

High serum levels of procalcitonin and soluble TREM-1 correlated with poor prognosis in pulmonary tuberculosis

SummaryObjectivesComparisons of procalcitonin (PCT), C-reactive protein (CRP), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) would expand our knowledge of which biomarker is the best predictor for outcomes of patients with pulmonary tuberculosis (PTB).MethodsWe prospectively enrolled 243 PTB patients, in whom PCT, CRP, and sTREM-1 measurement were performed to evaluate their prognostic value for 6-month mortality.ResultsSerum PCT, CRP, and sTREM-1 levels on diagnosis of PTB were significantly higher in nonsurvivors (2.22 ± 6.22 vs. 0.13 ± 0.31 ng/mL, P = 0.043; 42.1 ± 59.4 vs. 12.5 ± 29.1 mg/L, P = 0.004; 332 ± 362 vs. 128 ± 98 pg/mL, P = 0.001, respectively) as compared with 6-month survivors. In multivariate Cox regression analysis, PCT ≧0.5 ng/mL (hazard ratio 4.13, 95% CI, 1.99–8.58) and sTREM-1 ≧129 pg/mL (hazard ratio 3.39, 95% CI, 1.52–7.58) remained independent mortality predictors. Serum PCT and sTREM-1 levels above the cutoffs were also associated with the presence of disseminated tuberculosis.ConclusionsAmong PTB patients, higher PCT, CRP, and sTREM-1 levels are observed in nonsurvivors than in 6-month survivors. Serum levels of PCT and sTREM-1 over the cutoffs are independently associated with a poor outcome. In addition, higher PCT and sTREM-1 levels would raise the clinical suspicion of disseminated tuberculosis