Comparison of the temporal changes in the infarction volumes after focal cerebral ischemia between the saline and BNG-1 treatments.

<p>The T2-weighted image indicates that the infarction volume (white region) on the lesion cortex is smaller in the BNG-1 group than the saline group from as early as 4 h to 7 d. No striatum difference was observed. The bar in the pre-operation panels indicates 2.5 mm.</p

Comparison of the temporal expression of neurotrophic factor immunoreactivity after focal cerebral ischemia between the saline and BNG-1 treatments.

<p>The optical intensity of BDNF immunoreactivity on the lesion cortex is higher in the BNG-1 group than the saline group at 7 d, whereas no difference in NT-3 and NGF levels occurred at any time point. The bar in the sham panels indicates 100 µm.</p

Comparison of the temporal changes in the CBF after focal cerebral ischemia between the saline and BNG-1 treatments.

<p>CBF indicates that the postischemic hyperperfusion area (green area) is smaller in the BNG-1 group than the saline group at 4 h in both the lesion cortex and striatum, whereas no difference occurred after 2 d. The normal CBF region is blue. The bar in the pre-operation panels indicates 2.5 mm.</p

Comparison of the temporal changes in the maximal intensity projection after focal cerebral ischemia between the saline and BNG-1 treatments.

<p>The maximal intensity projection of the SWI indicates that the volume of the low signal intensity (cerebral vessels) is smaller in the BNG-1 group than the saline group in the striatum of both lesion and non-lesion hemispheres at 2 d. The bar in the pre-operation panels indicates 2.5 mm.</p