2 research outputs found
A Survey on Watching Social Issue Videos among YouTube and TikTok Users
The openness and influence of video-sharing platforms (VSPs) such as YouTube
and TikTok attracted creators to share videos on various social issues.
Although social issue videos (SIVs) affect public opinions and breed
misinformation, how VSP users obtain information and interact with SIVs is
under-explored. This work surveyed 659 YouTube and 127 TikTok users to
understand the motives for consuming SIVs on VSPs. We found that VSP users are
primarily motivated by the information and entertainment gratifications to use
the platform. VSP users use SIVs for information-seeking purposes and find
YouTube and TikTok convenient to interact with SIVs. VSP users moderately watch
SIVs for entertainment and inactively engage in social interactions. SIV
consumption is associated with information and socialization gratifications of
the platform. VSP users appreciate the diversity of information and opinions
but would also do their own research and are concerned about the misinformation
and echo chamber problems
Investigation of In vitro Release Kinetics of Carbamazepine from Eudragit® RS PO and RL PO Matrix Tablets
Purpose: The objective of this research work was to prepare and
evaluate the effect of Eudragit RS PO and Eudragit RL PO polymers on
the physical property and release characteristics of carbamazepine
matrix tablets. Methods: Matrix tablets containing carbamazepine were
prepared with Eudragit® RS PO alone as the rate-retarding polymer
(coded batch series ‘A’) and also with a combination of
Eudragit® RS PO and RL PO (coded batch series ‘B’).
The tablets were characterized for hardness as well as for
carbamazepine release. The release data were subjected to different
models in order to evaluate their release kinetics and mechanisms.
Results: The hardness of batch series ‘A’ matrix tablet
was >160 kg/cm2 while for batch series ‘B’, it was
>170 kg/cm2. Carbamazepine tablets containing only Eudragit RS PO
showed very slow release (less than 6% in 8 h) but when Eudragit RL PO
was blended with Eudragit RS PO, the release rate improved
significantly to 44% in 24 h (p < 0.05). Drug release mechanism was
a complex mixture of diffusion and erosion. Conclusion: Carbamazepine
matrix tablets of satisfactory hardness were produced. Furthermore, by
blending Eudragit RS PO with Eudragit RL PO in the matrix, tablets of
varying release characteristics can be prepared