Valoración de las competencias de los profesionales con maestría que demandan las escuelas de administración de empresas en las universidades más representativas del departamento de Lambayeque según el modelo UNED, 2015

El concepto de competencias se sigue implementando cada vez más en el ámbito laboral a nivel mundial, haciendo que las empresas requieran de colaboradores competentes, los cuales les permita tener mayor efectividad en las actividades profesionales que desempeñen. La presente investigación buscó determinar la valoración de las competencias de los profesionales con maestría que demandan las escuelas de administración de empresas en las universidades más representativas del departamento de Lambayeque, tomando como referencia el modelo UNED. La metodología que se utilizó para la valoración de dichas competencias radicó en la aplicación directa de encuestas y entrevistas a los encargados de la selección y reclutamiento de personal de las universidades más representativas del departamento de Lambayeque, lo cual permitió, conseguir información acerca de las exigencias en cuanto al perfil esperado que los profesionales con maestría deben tener para desempeñar de manera eficiente los desafíos que se les presentarán al instante de iniciar su vida laboral en dichas entidades. Con la culminación de este estudio se pudo determinar que las competencias más valoradas fueron la capacidad para tomar decisiones y para resolver conflictos, lo cual no deja de lado que los profesionales son conscientes de la necesidad de formarse en valores como la ética, la responsabilidad y el respeto hacia los demás fomentando así actitudes como el aprendizaje continuo y la pro actividad.Tesi

Comparisons of GnRH antagonist protocol versus GnRH agonist long protocol in patients with normal ovarian reserve: A systematic review and meta-analysis.

OBJECTIVE:To evaluate the effectiveness and safety of gonadotropin-releasing hormone antagonist (GnRH-ant) protocol and gonadotropin-releasing hormone agonist (GnRH-a) long protocol in patients with normal ovarian reserve. METHODS:We searched the PubMed (1992-2016), Cochrane Library (1999-2016), Web of Science (1950-2016), Chinese Biomedical Database (CBM, 1979-2016), and China National Knowledge Infrastructure (CNKI, 1994-2016). Any randomized controlled trials (RCTs) that compared GnRH-ant protocol and GnRH-a long protocol in patients with normal ovarian reserve were included, and data were extracted independently by two reviewers. The meta-analysis was performed by Revman 5.3 software. RESULTS:Twenty-nine RCTs (6399 patients) were included in this meta-analysis. Stimulation days (mean difference (MD) [95% confidence interval (CI)] = -0.8 [-1.36, -0.23], P = 0.006), gonadotrophin (Gn) dosage (MD [95% CI] = -3.52 [-5.56, -1.48], P = 0.0007), estradiol (E2) level on the day of human chorionic gonadotrophin (HCG) administration (MD [95% CI] = -365.49 [-532.93, -198.05], P<0.0001), the number of oocytes retrieved (MD [95% CI] = -1.41 [-1.84, -0.99], P<0.00001), the embryos obtained (MD [95% CI] = -0.99 [-1.38, -0.59], P<0.00001), incidence of ovarian hyperstimulation syndrome (OHSS) (OR [95% CI] = 0.69 [0.57, 0.83], P<0.0001) were statistically significantly lower in GnRH-ant protocol than GnRH-a long protocol. However, the clinical pregnancy rate (OR [95% CI] = 0.90 [0.80, 1.01], P = 0.08), ongoing pregnancy rate (OR [95% CI] = 0.88 [0.77, 1.00], P = 0.05), live birth rate (OR [95% CI] = 0.95 [0.74, 1.09], P = 0.27), miscarriage rate (OR [95% CI] = 0.98 [0.69, 1.40], P = 0.93), and cycle cancellation rate (OR [95% CI] = 0.86 [0.52, 1.44], P = 0.57) showed no significant differences between the two groups. CONCLUSION:GnRH-ant protocol substantially decreased the incidence of OHSS without influencing the pregnancy rate and live birth rate compared to GnRH-a long protocol among patients with normal ovarian reserve

Alterations in Vaginal Microbiota and Associated Metabolome in Women with Recurrent Implantation Failure

In vitro fertilization-embryo transfer (IVF-ET) is now widely applied for treating infertility, and unexplained recurrent implantation failure (RIF) has become a substantial challenge. We hypothesize that vaginal microbial dysbiosis is associated with RIF, as it is linked to many female reproductive diseases. In this study, we characterized the vaginal microbiota and metabolomes of patients with unexplained RIF, while patients who achieved clinical pregnancy in the first IVF cycle were set as controls. In general, significant differences were discovered in the vaginal microbiota and metabolomes between the two groups. This study is the first detailed elaboration of the vaginal microbiota and metabolites associated with RIF. We believe that our findings will inspire researchers to consider the dynamics of microbiomes related to the microenvironment as a critical feature for future studies of nosogenesis not only for RIF but also for other reproductive diseases.Recurrent implantation failure (RIF) refers to repeated failure to become pregnant after transferring embryos with normal morphology. However, the pathogenesis of RIF remains unrevealed, especially for those without any pathological features. In this study, we characterized the vaginal microbiota and metabolomes of patients with unexplained RIF, while patients who achieved clinical pregnancy in the first frozen embryo transfer (FET) cycle were used as controls. Based on 16S rRNA gene sequencing of the vaginal microbiota, the vaginal Lactobacillus showed a significant positive correlation with the pregnancy rate, and the RIF group presented higher microbial α-diversity than the control group (P value = 0.016). The metabolomic profile identified 2,507 metabolites, of which 37 were significantly different between the two groups (P value  1). Among them, 2′,3-cyclic UMP and inositol phosphate were the top two metabolites that were higher in the RIF group, while glycerophospholipids and benzopyran were important metabolites that were lower in the RIF group. A lack of lysobisphosphatidic acid and prostaglandin metabolized from glycerophospholipids will lead to deferred implantation and embryo crowding. Benzopyran, as a selective estrogen receptor modulator, may affect the outcome of pregnancy. All of the changes in metabolite profiles may result in or from the differential microbiota compositions in RIF patients. In conclusion, significant differences were presented in the vaginal microbiota and metabolomes between patients with unexplained RIF and women who became pregnant in the first FET cycle. For the first time, this study elaborates the possible pathogenesis of RIF by investigating the vaginal microbiota and metabolites in RIF patients

Preparation and characterization of lanthanum borate nanowires

Lanthanum borate nanowires had been fabricated by reacting lanthanum oxide and boron with carbon nanotubes at 1100 °C. Electron microscopy studies show that the nanowires have a single-crystal structure with uniform diameters of ∼ 15 nm and lengths up to several micrometers. The growth mechanism of LaBO3 nanowires could be basically attributed to a CNTs template-confined reaction process; carbon nanotubes confine the reaction in a local space during the reaction. The morphology of lanthanum borate nanowires depends on the shape of the carbon nanotubes at high reaction temperatures

Forest plot comparing the live birth rate per woman randomized between the GnRH-ant group and the GnRH-a long-protocol group.

<p>Forest plot comparing the live birth rate per woman randomized between the GnRH-ant group and the GnRH-a long-protocol group.</p

Forest plot comparing the E2 level on the day of HCG administration per woman randomized between the GnRH-ant group and the GnRH-a long-protocol group.

<p>Forest plot comparing the E2 level on the day of HCG administration per woman randomized between the GnRH-ant group and the GnRH-a long-protocol group.</p

Characteristics of included studies.

<p>Characteristics of included studies.</p