大腸癌細胞DLD-1腫瘍移植マウスにおける腫瘍診断薬3-[125I] iodo-α-methy1-L-tyrosineのprobenecid前投与による体内動態制御法

取得学位 : 博士（保健学）, 学位授与番号 : 医博甲第1898号 , 学位授与年月日 : 平成19年9月28日, 学位授与大学 : 金沢大学, 審査結果の報告日 : 平成19年8月24日, 主査 :川井 惠一 , 副査 :高山 輝彦, 天野 良

On the Characteristic Difference of Neoclassical Bootstrap Current and Its Effects on MHD Equilibria between CHS Heliotron/Torsatron and CHS-qa Quasi-Axisymmetric Stellarator

The characteristic difference of neoclassical bootstrap current and its effects on MHD equilibria are described for the CHS heliotron/torsatron and the CHS-qa quasi-axisymmetric stellarator. The direction of bootstrap current strongly depends on collisionality in CHS, whereas it does not in CHS-qa because of quasi-axisymmetry. In the CHS configuration, it appears that enhanced bumpy (Bs1) and sideband components of helical ripple (By1) play an important role in reducing the magnetic geometrical factor, which is a key factor in evaluating the value of bootstrap cuffent, and determining its polarity. The bootstrap current in CHS-qa is theoretically predicted to be larger than that in CHS and produces significant effects on the resulting rotational transform and magnetic shear. In the finite B plasmas, the magnetic well becomes deeper in both CHS and CHS-qa and its region is expanded in CHS. The existence of co-flowing bootstrap current makes the magnetic well shallow in comparison with that in currentless equilibrium

Orbit Topology and Confinement of Energetic Ions in the CHS-qa Quasi-Axisymmetric Stellarator

The orbit topology and confinement of neutral beam-injected energetic ions are investigated for the current target configuration of the CHS-qa quasi-axisymmetric stellarator. It was shown that tangentially co-injected neutral beam (NB) heating is efficient even at a low magnetic field strength Bt of 0.5 T, whereas the heating efficiency of the counter-injected NB becomes significantly lower as Bt decreases because of the increase of first orbit loss. The energy loss rate increases as the beam injection angle becomes perpendicular, suggesting that the residual non-axisymmetric ripple in the peripheral domain plays a role in enhancing the transport of trapped ions. An interesting observation involves the appearance of the island structure in both the gyro motion following orbit and the guiding center collisionless orbit of counter-moving transit beam ions. It appears under a particular, narrow range of parameters, i.e., energy, pitch angle v///v, normalized minor radius r/a at the launching point and Bt

Effects of Current Profile on Global Ideal MHD Stability in a Compact Quasi-Axisymmetric Stellarator

The global ideal magnetohydrodynamic (MHD) stability for a proposed compact quasi-axisymmetric stellarator CHS-qa has been investigated taking the effect of bootstrap current into account. Assuming experimentally achievable density and temperature profiles, the stability properties of global low-n modes have been studied by using threedimensionalnumerical codes based on fixed boundary MHD equilibria including self-consistent bootstrap current for the CHS-qa reference configuration. Consequently it has been shown that values of edge rotational transform play a crucial role in triggering external kink instability. Concerning a lot of other possibilities in experimental practice to change the total parallel current, we have also studied equilibria with increased or decreased parallel current, but fixed profile. The onset of external kink modes depends on rotational transform or current profile, and we found a stable equilibrium in spite of the edge rotational transform above 0.5. The results imply the possibility of stabilizing external kink modes through current and/or pressure profile control in high beta equilibria