1 research outputs found
Formal [4 + 1]-Cycloaddition of Homopropargyl Alcohols to Diazo Dicarbonyl Compounds Giving Substituted Tetrahydrofurans
A novel
formal [4 + 1]-cycloaddition of readily available homopropargyl
alcohols with diazo dicarbonyl compounds is described, which involves
tandem O–H insertion/Conia-ene cyclization under cooperative
RhÂ(II)/ZnÂ(II) catalysis. This reaction provides easy access to various
substituted tetraÂhydroÂfurans and exhibits complete <i>E</i>-selectivity in the case of nonterminal alkynes