Monte-Carlo Simulation of Domain-Wall Network in Two-dimensional Extended Supersymmetric Theory

We will show that 2-dimensional N=2-extended supersymmetric theory can have solitonic solution using the Hamilton-Jacobi method of classical mechanics. Then it is shown that the Bogomol'nyi mass bound is saturated by these solutions and triangular mass inequality is satisfied. At the end, we will mention domain-wall structure in 3-dimensional spacetime.Comment: Talk given at International Symposium on Non-Equilibrium and Nonlinear Dynamics in Nuclear and Other Finite Systems held at May 21-25, 2001 in Beijing. 7 pages, 4 figure

ステロイド テイコウセイ Kasabach-Merritt ショウコウグン ニ タイスル テイセンリョウ ホウシャセン チリョウ

From 1990 to 2001, a total of five hemangioma patients with Kasabach-Merritt syndrome received radiation therapy at Tohoku University Hospital. Steroids were administered before, during and after radiation therapy to all of the patients and interferon-α was administered to two patients. Radiation therapy was administered with a 4 MV X-ray was in four patients and a 12 MeV electron in one patient. Planned target volume included hemangioma with a 1-2 cm margin in all directions. A radiation dose of 3-3.5Gy was administered in 3-5 fractions. Rapid and transient increase of platelet count was observed in three patients. In two patients, an additional course of radiation was administered and the second course of radiation seemed to be effective for both. Of the three patients with hemangioma of the extremities, growth inhibition of irradiated extremities was not observed, and, in fact, elongation of extremities was observed in two patients. In one patient, lymphangioma developed from irradiated hemangioma. Although no serious late complications were observed in our series, 3-3.5Gy of radiation therapy for KMS seems to be insufficient to obtain rapid and stable improvement of thrombocytopenia.　Key words：Kasabach-Merritt syndrome, Radiation therapy, Low-dos

Free Will and the Divergence Problem

This paper presents what the authors call the ‘divergence problem’ regarding choosing between different future possibilities. As is discussed in the first half, the central issue of the problem is the difficulty of temporally locating the ‘active cause’ on the modal divergent diagram. In the second half of this paper, we discuss the ‘second-person freedom’ which is, strictly, neither compatibilist negative freedom nor incompatibilist positive freedom. The divergence problem leads us to two hypothetical views (i.e. the view of single-line determination and that of one-off chance), and these views bring humans closer to the afree side – i.e. outside of the contrast between being free and being unfree. The afree side is greatly different from the ordinary human side. This paper tries to secure the second-person freedom as a substitute for the ordinary human freedom while preventing the divergence problem from arising

亜鉛イオン濃度変化は脂肪由来幹細胞から作成するインスリン産生細胞の成熟を反映する

The generation of insulin-producing cells (IPCs) from pluripotent stem cells could be a breakthrough treatment for type 1 diabetes. However, development of new techniques is needed to exclude immature cells for clinical application. Dithizone staining is used to evaluate IPCs by detecting zinc. We hypothesised that zinc ion (Zn2+) dynamics reflect the IPC maturation status. Human adipose-derived stem cells were differentiated into IPCs by our two-step protocol using two-dimensional (2D) or 3D culture. The stimulation indexes of 2D -and 3D-cultured IPCs on day 21 were 1.21 and 3.64 (P < 0.05), respectively. The 3D-cultured IPCs were stained with dithizone during culture, and its intensity calculated by ImageJ reached the peak on day 17 (P < 0.05). Blood glucose levels of streptozotocin-induced diabetic nude mice were normalised (4/4,100%) after transplantation of 96 3D-cultured IPCs. Zn2+ concentration changes in the medium of 3D cultures had a negative value in the early period and a large positive value in the latter period. This study suggests that Zn2+ dynamics based on our observations and staining of zinc transporters have critical roles in the differentiation of IPCs, and that their measurement might be useful to evaluate IPC maturation as a non-destructive method

Hardness Perception Based on Dynamic Stiffness in Tapping

A human can judge the hardness of an object based on the damped natural vibration caused by tapping the surface of the object using a fingertip. In this study, we investigated the influence of the dynamic characteristics of vibrations on the hardness perceived by tapping. Subjectively reported hardness values were related to the dynamic stiffness of several objects. The dynamic stiffness, which characterizes the impulsive response of an object, was acquired across the 40–1,000 Hz frequency range for cuboids of 14 types of materials by administering a hammering test. We performed two psychophysical experiments—a ranking task and a magnitude-estimation tasks—wherein participants rated the perceived hardness of each block by tapping it with a finger. We found that the perceptual effect of dynamic stiffness depends on the frequency. Its effect displayed a peak around 300 Hz and decreased or disappeared at higher frequencies, at which human perceptual capabilities are limited. The acquired results help design hardness experienced by products