4-[2-(4-Chloro­phen­yl)hydrazinyl­idene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothio­amide

In the title mol­ecule, C11H10ClN5OS, an intra­molecular N—H⋯O hydrogen forms an S(6) ring motif. The dihedral angle between the pyrazole ring and the benzene ring is 3.77 (8)°. In the crystal, mol­ecules are linked by N—H⋯S and N—H⋯O hydrogen bonds into layers parallel to the bc plane

Ethyl 2-[2-(2-meth­oxy­phen­yl)hydrazinyl­idene]-3-oxobutano­ate

In the title compound, C13H16N2O4, an intra­molecular N—H⋯O hydrogen bond generates an S(6) ring. The mol­ecule adopts an E configuration with respect to the central C=N double bond. In the crystal, symmetry-related mol­ecules are connected into chains along [010] via weak C—H⋯N hydrogen bonds. The crystal structure is further stabilized by weak C—H⋯π inter­actions

The Influence of Emotional States on Short-Term Memory Retention by Using Electroencephalography (EEG) Measurements: A Case Study

The electroencephalogram (EEG) is a non-invasive test that records the electrical activity of the brain as wave patterns generated by various brain structures. The electrical activity is recorded from the scalp surface after being picked up by metal electrodes (small metal discs) and conductive media. This study explored how emotions can impact short-term memory retention, and thus the process of learning, by analyzing five mental tasks: relaxation, memorization of ten words, memorization of ten two-digit numbers, visual exposure to emotional stimuli, and recall of the 10 words and 10 numbers. The word list contained ten words as five event-related (directly related to the type of emotion triggered) and five not event-related words. The visual task was separated into three categories corresponding to the type of image extracted from the public domain International Affective Picture System (IAPS) library, which in turn correspond to three emotional states assumed to be evoked by them: neutral, negative (e.g. sadness), and positive (e.g. happiness). Event-related potentials (ERP) were measured by EEG with the ANT Neuro system. The ASA software and EEGLab were utilized for the analysis of ERPs in five EEG bands: Delta (0-3.9Hz), Theta (4-7.9Hz), Alpha (8-12.9Hz), Beta (13-30 Hz), and Gamma (31-50 Hz). Eleven participants (ten males and one female between 20 and 25 years old) were included in this case study. To date, no other studies have been reported to use EEG measurements in the evaluation of the influence of emotional states on short-term memory retention

3-Methyl-5-oxo-4-(2-phenyl­hydrazinyl­idene)-4,5-dihydro-1H-pyrazole-1-carbothio­amide

In the title compound, C11H11N5OS, the pyrazole ring is approximately planar, with a maximum deviation of 0.010 (2) Å. The dihedral angles between the benzene ring and the pyrazole and carbothio­amide groups are 5.42 (9) and 10.61 (18)°, respectively. An intra­molecular N—H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, mol­ecules are connected by inter­molecular N—H⋯O and C—H⋯S hydrogen bonds, forming R 2 2(12) ring motifs. In addition, there is a π–π stacking inter­action [centroid–centroid distance = 3.5188 (11) Å] between the pyrazole and benzene rings. These inter­actions link the mol­ecules into infinite chains along [001]

MANAGEMENT OF STRESS RELATED PSORIASIS W. S. R. TO CHETAH SAMAVAYI

There is a wide range of importance for appearance in present era. Psoriasis is chronic disorder which is commonly encountered in day to days clinical practices. It is one of the burning issue having social importance. Increased stress and life style are main predisposing factor which is accounting for wide spared prevalence of this disease. Usually10-15% cases present before general practitioners are pertaining to skin diseases. Due to altered life style, lack of physical exercise, unhygienic, mental stress, over eating, skin diseases are commonly observed. We can observe many diseases popping up especially due to mental stress i.e., Manasa Vikriti. There is Samavaya Sambandha between Tvacha and Manas (Chetah Samavayi). Most of the Tvak Vikaras are psychologically agonising and have negative impact on quality of life. Here it is important to remember the citation of Acharya Charaka regarding the relationship between the Tvacha and Manas, Tvacha is considered as Chetah Samvayi i.e., the skin has an eternal relationship with Manas (psyche/mind). The knowledge of Nidana is helpful for the proper diagnosis, prevention of disease and treatment also. Thus to treat any Tvak Gata Vikara, Bhishak should consider the skin ailment as well as condition of Manas. This paper highlights a case study of stress related Kitibha Kusta (Psoriasis) treated with Shodhana Chikitsa.

3-Methyl-5-phen­oxy-1-phenyl-1H-pyrazole-4-carbaldehyde

In the title compound, C17H14N2O2, the pyrazole ring makes dihedral angles of 73.67 (4) and 45.99 (4)°, respectively, with the adjacent phenyl and phen­oxy rings. In the crystal, there are no classical hydrogen bonds, but a weak C—H⋯π inter­action is observed

4-[2-(2-Meth­oxy­phen­yl)hydrazinyl­idene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothio­amide

In the title mol­ecule, C12H13N5O2S, a bifurcated intra­molecular N—H⋯O(O) hydrogen bond forms two S(6) ring motifs. The benzene ring forms a dihedral angle of 14.36 (11)° with the pyrazole ring. In the crystal, pairs of N—H⋯S hydrogen bonds form centrosymmetric dimers, generating R 2 2(8) ring motifs, which stack along the b axis

4-[2-(4-Bromo­phen­yl)hydrazinyl­idene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothio­amide

In the title compound, C11H10BrN5OS, the approximately planar pyrazole ring [maximum deviation = 0.014 (2) Å] forms a dihedral angle of 5.49 (13)° with the benzene ring. An intra­molecular N—H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, mol­ecules are linked through inter­molecular N—H⋯S and N—H⋯O hydrogen bonds, forming a two-dimensional network parallel to (100). A short Br⋯Br contact of 3.5114 (6) Å is also observed

2,3-Dibromo-3-(5-nitro-2-fur­yl)-1-(4-nitro­phen­yl)propan-1-one

In the title compound, C13H8Br2N2O6, the 2-furyl ring is essentially planar, with a maximum deviation of 0.002 (2) Å. It is inclined at an angle of 33.94 (9)° to the benzene ring. Both nitro groups are slightly twisted away from their attached rings; the dihedral angles are 4.6 (2)° between the nitro group and the 2-furyl ring, and 13.72 (19)° between the nitro group and the benzene ring. In the crystal, mol­ecules are linked into chains along [110] and [10] via two pairs of inter­molecular C—H⋯O hydrogen bonds, displaying R 2 2(10) ring motifs

2,3-Dibromo-1-(4-chloro­phen­yl)-3-(5-nitro-2-fur­yl)propan-1-one

In the title compound, C13H8Br2ClNO4, the linking –CHBr–CHBr– fragment is disordered over two orientations with refined site occupancies of 0.512 (11) and 0.488 (11). The dihedral angle between the furan ring and the phenyl ring is 21.86 (16)°. In the crystal, the mol­ecules are linked into [011] chains by inter­molecular C—H⋯O hydrogen bonds