Investigations on the Flexural Strength and the Effect of b/h and l/b ratio on the Carbon Fiber Reinforced Epoxy Laminated Composites

In present day the use of fiber reinforced composites is increased remarkably in the various sectors of industries owing to its relative advantages especially in industries like aeronotics, automobile, ship buildingand in chemical industries, where the major emphasis is on weight reduction with a subtantial increase in the mechanical strengt h of the component with enhanced durabli ty by having properties like corrosive resistance, anti reactive to various acidic reactions and to with stand various climatic and temperature conditions.In this context carbon fibre reinforced laminated composites exhibit excellent mechanical properties.Investigation of various properties is difficult in composite materials because of its complex behavior further it is very difficult to evaluate the behavior of fiber laminated composites because of its enhanced complexity,evaluation of properties in composites is difficult with the addition of the fiber (carbon fiber)into the matrix. in this paper an investigation on the flexural properties of the carbon fiber reinforced laminates is carried out and the effect of bredth(b)to thickness(t)and the influence of the of length(l)to breadth(b),Aspect ratiois being evaluated and appropriate conclusions are drawn

Evaluation of Modal Damping of Graphite/ Epoxy Laminated Composites

The damping of an engineering structure is important in many aspects of noise and vibration control, fatigue endurance and so on, since it controls the amplitude of resonant vibration esponse. Damping in fiber-reinforced composite aterials is highly tailorable with respect to constituent roperties, fiber volume fractions and ply orientation angles.To this end an experimental analysis of the damping of unidirectional graphite reinforced epoxy composites was carried out. Damping characteristics of laminates are analysed experimentally using impulse technique. Composite laminate were made using the traditional hand-lay -up process. Experimental dynamic tests were carried out using specimens with different fiber orientations and three different boundary conditions and different thickness

NKS1/ELMO4 is an integral protein of a pectin synthesis protein complex and maintains Golgi morphology and cell adhesion in Arabidopsis

Adjacent plant cells are connected by specialized cell wall regions, called middle lamellae, which influence critical agricultural characteristics, including fruit ripening and organ abscission. Middle lamellae are enriched in pectin polysaccharides, specifically homogalacturonan (HG). Here, we identify a plant- specific Arabidopsis DUF1068 protein, called NKS1/ELMO4, that is required for middle lamellae integrity and cell adhesion. NKS1 localizes to the Golgi apparatus and loss of NKS1 results in changes to Golgi structure and function. The nks1 mutants also display HG deficient phenotypes, including reduced seedling growth, changes to cell wall composition, and tissue integrity defects. These phenotypes are comparable to qua1 and qua2 mutants, which are defective in HG biosynthesis. Notably, genetic interactions indicate that NKS1 and the QUAs work in a common pathway. Protein interaction analyses and modeling corroborate that they work together in a stable protein complex with other pectin- related proteins. We propose that NKS1 is an integral part of a large pectin synthesis protein complex and that proper function of this complex is important to support Golgi structure and function. Significance Cell walls are essential to cell morphogenesis, to protect plants against environmental stress, and for an array of products in our daily life. Understanding how plants produce cell wall polymers is therefore important. In this study, we outline how a family of unknown proteins function as a scaffold for key synthesis components of pectin, a central cell wall polymer. Our results thus define a robust pectin synthesis protein complex that is essential for the structure and function of Golgi and for plant tissue integrity. These results add critical information regarding pectin synthesis and cell wall metabolons

Pre-operative ondansetron vs. metoclopramide for prevention of post-operative nausea and vomiting in elective lower-segment caesarean section under spinal anaesthesia

Background: The problem of nausea and vomiting is a very old but a less thought of problem. Nausea and vomiting are the most common distressing symptom in the postoperative period. Antiemetic drugs play an important role in therapy of post-operative nausea and vomiting (PONV). Though many drugs have been tried as prophylaxis and treatment of PONV, no drug has been proved significantly effective and hence, the present study was undertaken to compare the efficacy and safety of IV metoclopramide and IV Ondansetron as prophylaxis for postoperative nausea and vomiting in lower-segment caesarean section (LSCS) under spinal anaesthesia. Methods: After institutional approval and informed consent 100 ASA I & II patients undergoing non emergent LSCS taken for study. The patients were divided randomly into 2 groups of 50 each. Group I received IV metoclopramide 10mg and Group II received IV. Ondansetron 4mg. Anaesthetic management was standardized. The incidence of vomiting and retching as number of episodes was studied. Nausea was graded depending on the severity and data derived. Results: The mean age, weight and duration of surgery was not significantly different when compared group-1 parturiants with group-2. The mean episodes of emesis, nausea and retching at different postoperative duration were significantly decreased (p<0.05) in Ondansetron group when compared to metoclopramide group as postoperative time progresses. Conclusions: Injection ondansetron 4mg provided decrease in the incidence of PONV than metoclopramide as the side effects with these drugs were minimal.

A Study on Effect of Variation of Thickness on Tensile Properties of Hybrid Polymer Composites (Glassfibre-Carbonfibre-Graphite) and GFRP Composites

Increase in demand of advanced materials to satisfy the requirements of aerospace and automotive industry viz. high modulus to density ratio, leads to the research in composite materials where an attempt is made to study the properties of composite materia ls by composing the different materials together to obtain the desired properties by reducing the weight as much as possible. Here an attempt is made to study the behavior and tensile properties of Hybrid polymer composite material by composing E-glass fibres, carbon fibres and graphite with epoxy resin 5052.By the variation of thickness. Tensile strength of hybrid composite is observed for each thickness and is optimized and compared with the properties of standalone glass fibre reinforced composites for the same variation of thickness. The comparison represents the enhancement of tensile strength and cost effectiveness by the introduction of multiple materials (Hybridomposites)

A Study on Inventory Management in Manufacturing Industry with specific reference to Bangalore

The study evaluates inventory control aspects, including turnover, stock outs, carrying costs, and order fulfilment rates.Commendable aspects of industryof current practices include maintaining adequate stock levels and minimizing excess inventory. However, opportunities for improvement lie in enhancing demand forecasting accuracy and real-time stock monitoring. The study suggests integrating advanced technologies and data analytics to address these gaps. Using the secondary data of the balance sheet we have analysed the inventory turnover, growth of total inventory, current assets on raw materials. Also, we have analysed the ABC analysis of the materials. The result shows that the business has maintained a relatively high percentage of inventories on current assets, indicating its reliance on inventory as a key asset

Mechanochemical feedback mediates tissue bending required for seedling emergence

Tissue bending is vital to plant development, as exemplified by apical hook formation during seedling emergence by bending of the hypocotyl. How tissue bending is coordinated during development remains poorly understood, especially in plants where cells are attached via rigid cell walls. Asymmetric distribution of the plant hormone auxin underlies differential cell elongation during apical hook formation. Yet the underlying mechanism remains unclear. Here, we demonstrate spatial correlation between asymmetric auxin distribution, methylesterified homogalacturonan (HG) pectin, and mechanical properties of the epidermal layer of the hypocotyl in Arabidopsis. Genetic and cell biological approaches show that this mechanochemical asymmetry is essential for differential cell elongation. We show that asymmetric auxin distribution underlies differential HG methylesterification, and conversely changes in HG methylesterification impact the auxin response domain. Our results suggest that a positive feedback loop between auxin distribution and HG methylesterification underpins asymmetric cell wall mechanochemical properties to promote tissue bending and seedling emergence

A review of hyperandrogenism state in polycystic ovarian syndrome

Polycystic ovary syndrome is one of the most prevalent endocrinopathy in premenopausal women. The pathophysiology of PCOS is not clear, however disturbance in the hypothalamic-pituitary-ovarian axis and abnormal steroidogenesis along with genetic and environmental factors act as main contributors to this disorder. The steroidogenic pathway is affected by the overexpression of the CYP11A, CYP17, and CYP19 genes in PCOS, which results in a hyperandrogenic condition. The initial effect of too much androgen in PCOS is impaired folliculogenesis. The most frequent clinical manifestations of hyperandrogenism in women with PCOS include hirsutism, acne, and androgenic alopecia. Women with PCOS may have an excess of androgen during foetal life due to the elevated expression of P450c17a during the whole pregnancy. PCOS is believed to be formed in utero by the influence of androgen excess on gene expression in adolescence and adulthood, which offers more solid evidence that real PCOS can be induced by prenatal androgenization. A prenatal androgen excess-induced epigenetic phenomena is suggested by the current theory of PCOS's developmental genesis. It is currently believed that the many tiny follicles seen in polycystic ovaries and the considerable irregularity in the very early stages of folliculogenesis are associated to the formation of anovulation in PCOS

OPTIMIZATION OF SOLID WASTE MANAGEMENT USING GEOGRAPHIC INFORMATION SYSTEM (GIS) FOR DURG CITY

A rapid urbanization, surging population numbers, limitations of funding, emerging limitations of both energy and raw materials coupled with different increasing industrial, commercial and Social economic development in a durg city. The Durg city area has given rise to an increased generation of various types of wastes. Among these wastes, managing of solid waste is a major problem faced by the Durg city. The Durg city maintaining daily logs of collection and transport of solid waste is time consuming and difficult as it involves large filed data and statistics. 80% of the total cost of solid waste management is being spent on collection and transportation so there is to a need of proper monitoring of the system. This paper attempts to analyze the proposed status of location of municipal bins along with the various secondary routes followed for the solid waste collection of durg city. Then using Arc GIS 10 , a GIS based urban MSW management system is proposed for the study area by proper optimizing the waste collection and transportation routes and reallocating the bins  for efficiency in distance travelled and time taken. Thus Geographical Information System model would reduce the complications in waste management system to some extent and exhibit remedies for the same in the study area