Correlation between serum klotho levels and IGF-1 (as assessed with the Pearson correlation coefficient).

<p>Correlation between serum klotho levels and IGF-1 (as assessed with the Pearson correlation coefficient).</p

Laboratory measurements according to GH status.

<p>OGHD: organic growth hormone deficiency; IGHD: idiopathic growth hormone deficiency.</p><p>*GH sufficient compared to organic and idiopathic GHD.</p><p>**Organic GHD compared to both other groups.</p><p>Laboratory measurements according to GH status.</p

Clinical and anthropometric characteristics according to GH status^$.

<p>GH: growth hormone; GHD: growth hormone deficiency; Δ height-SDS: difference between participants’ height SDS and the genetic target height (height-SDS - MPH^‡-SDS); BA/CA: ratio between bone age and chronological age.</p>

Continuous variables were compared using one way ANOVA; categorical variables (gender, pubertal state) were compared using the Chi-square (χ2) test.

*Organic GHD lower than both Idiopathic GHD and GHS.

**Idiopathic GHD higher than both organic GHD and GHS.

***GHS significantly lower than IGHD.

‡

MPH: Mid-parental height (average of the heights of the parents, plus 6.5 cm for male patients and minus 6.5 cm for females).

Clinical and anthropometric characteristics according to GH status^</a>.</p</sup>