4 research outputs found
Berry v. State, 131 Nev. Adv. Op. No. 96 (Dec. 24, 2015)
The issue before the Court was an appeal from a district court order dismissing a post-conviction petition for writ of habeas corpus. The Court reversed and remanded holding that the district court improperly discounted the declarations in support of the appellantâs petition, which included a confession of another suspect, whom the petitioner implicated as the real perpetrator at trial. The Court held that these declarations were sufficient to merit discovery, and an evidentiary hearing on Petitioner Berryâs gateway actual innocence claim
State v. Merlino, 131 Nev. Adv. Op. No. 65 (Sept. 10, 2015)
The issue before the Court was whether selling stolen property through a retractable sliding tray on a pawn shopâs drive-through window satisfied the element of unlawful entry of a building as defined in the burglary statute. The Court held that when the outer boundary of a building is not self-evident from the shape and contours of the structure itself, courts must apply Californiaâs âreasonable beliefâ test which legally defines the outer boundary to include, âany element that encloses an area into which a reasonable person would believe that a member of the general public could not pass without authorization.
Photopolymerized Cross-Linked ThiolâEne Polyanhydrides: Erosion, Release, and Toxicity Studies
Several
critical aspects of cross-linked polyanhydrides made using
thiolâene polymerization are reported, in particular the erosion,
release, and solution properties, along with their cytotoxicity toward
fibroblast cells. The monomers used to synthesize these polyanhydrides
were 4-pentenoic anhydride and pentaerythritol tetrakisÂ(3-mercaptopropionate).
Techniques used to evaluate the erosion mechanism indicate a complex
situation in which several phenomena, such as hydrolysis rates, local
pH, water diffusion, and solubility, may be influencing the erosion
process. The mass loss profile, the release rate of a hydrophilic
dye, the rate of hydrolysis of the polyanhydride, the hydrolysis product
solubility as a function of pH, average p<i>K</i><sub>a</sub> and its cytotoxicity toward fibroblast cells were all determined.
The solubility of the degradation product is low at pH values less
than 6â7, and the average p<i>K</i><sub>a</sub> was
determined to be âŒ5.3. The cytotoxicity of the polymer and
the degradation product was found to be low, with cell viabilities
of >97% for the various samples studied at concentrations of âŒ1000â1500
ppm. These important parameters help determine the potential of the
thiolâene polyanhydrides in various biomedical applications.
These polyanhydrides can be used as a delivery vehicle, and although
the release profile qualitatively followed the mass loss profile for
a hydrophilic dye, the release rate appears to be by both diffusion
and mass loss mechanisms