635 research outputs found
Classification of Singular Fibres on Rational Elliptic Surfaces in Characteristic Three
We determine and list all possible configurations of singular fibres on
rational elliptic surfaces in characteristic three. In total, we find that 267
distinct configurations exist. This result complements Miranda and Persson's
classification in characteristic zero, and Lang's classification in
characteristic two.Comment: 40 Pages. Minor typos correcte
Magnetic-Field-Induced Antiferromagnetism in Two-Dimensional Hubbard Model: Analysis of CeRhIn
We propose the mechanism for the magnetic-field-induced antiferromagnetic
(AFM) state in a two-dimensional Hubbard model in the vicinity of the AFM
quantum critical point (QCP), using the fluctuation-exchange (FLEX)
approximation by taking the Zeeman energy due to the magnetic field into
account. In the vicinity of the QCP, we find that the AFM correlation
perpendicular to is enhanced, whereas that parallel to is reduced. This
fact means that the finite magnetic field increases , with the AFM order
perpendicular to . The increment in can be understood in terms of the
reduction of both quantum and thermal fluctuations due to the magnetic field,
which is caused by the self-energy effect within the FLEX approximation. The
present study naturally explains the increment in in CeRhIn_5 under the
magnetic field found recently.Comment: 5 page
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Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs
Pluripotent stem cell-derived human primordial germ cell-like cells (hPGCLCs) provide important opportunities to study primordial germ cells (PGCs). We robustly produced CD38+ hPGCLCs [∼43% of FACS-sorted embryoid body (EB) cells] from primed-state induced pluripotent stem cells (iPSCs) after a 72-hour transient incubation in the four chemical inhibitors (4i)-naïve reprogramming medium and showed transcriptional consistency of our hPGCLCs with hPGCLCs generated in previous studies using various and distinct protocols. Both CD38+ hPGCLCs and CD38− EB cells significantly expressed PRDM1 and TFAP2C, although PRDM1 mRNA in CD38− cells lacked the 3′-UTR harboring miRNA binding sites regulating mRNA stability. Genes up-regulated in hPGCLCs were enriched for cell migration genes, and their promoters were enriched for the binding motifs of TFAP2 (which was identified in promoters of T, NANOS3, and SOX17) and the RREB-1 cell adhesion regulator. In EBs, hPGCLCs were identified exclusively in the outermost surface monolayer as dispersed cells or cell aggregates with strong and specific expression of POU5F1/OCT4 protein. Time-lapse live cell imaging revealed active migration of hPGCLCs on Matrigel. Whereas all hPGCLCs strongly expressed the CXCR4 chemotaxis receptor, its ligand CXCL12/SDF1 was not significantly expressed in the whole EBs. Exposure of hPGCLCs to CXCL12/SDF1 induced cell migration genes and antiapoptosis genes. Thus, our study shows that transcriptionally consistent hPGCLCs can be readily produced from hiPSCs after transition of their pluripotency from the primed state using various methods and that hPGCLCs resemble the early-stage PGCs randomly migrating in the midline region of human embryos before initiation of the CXCL12/SDF1-guided chemotaxis
The HIV-1 Gp120/CXCR4 Axis Promotes CCR7 Ligand-Dependent CD4 T Cell Migration: CCR7 Homo- and CCR7/CXCR4 Hetero-Oligomer Formation as a Possible Mechanism for Up-Regulation of Functional CCR7
During human immunodeficiency virus (HIV) infection, enhanced migration of infected cells to lymph nodes leads to efficient propagation of HIV-1. The selective chemokine receptors, including CXCR4 and CCR7, may play a role in this process, yet the viral factors regulating chemokine-dependent T cell migration remain relatively unclear. The functional cooperation between the CXCR4 ligand chemokine CXCL12 and the CCR7 ligand chemokines CCL19 and CCL21 enhances CCR7-dependent T cell motility in vitro as well as cell trafficking into the lymph nodes in vivo. In this study, we report that a recombinant form of a viral CXCR4 ligand, X4-tropic HIV-1 gp120, enhanced the CD4 T cell response to CCR7 ligands in a manner dependent on CXCR4 and CD4, and that this effect was recapitulated by HIV-1 virions. HIV-1 gp120 significantly enhanced CCR7-dependent CD4 T cell migration from the footpad of mice to the draining lymph nodes in in vivo transfer experiments. We also demonstrated that CXCR4 expression is required for stable CCR7 expression on the CD4 T cell surface, whereas CXCR4 signaling facilitated CCR7 ligand binding to the cell surface and increased the level of CCR7 homo-as well as CXCR4/CCR7 hetero-oligomers without affecting CCR7 expression levels. Our findings indicate that HIV-evoked CXCR4 signaling promotes CCR7-dependent CD4 T cell migration by up-regulating CCR7 function, which is likely to be induced by increased formation of CCR7 homo-and CXCR4/CCR7 hetero-oligomers on the surface of CD4 T cells.</p
Anomaly Cancelation in Field Theory and F-theory on a Circle
We study the manifestation of local gauge anomalies of four- and
six-dimensional field theories in the lower-dimensional Kaluza-Klein theory
obtained after circle compactification. We identify a convenient set of
transformations acting on the whole tower of massless and massive states and
investigate their action on the low-energy effective theories in the Coulomb
branch. The maps employ higher-dimensional large gauge transformations and
precisely yield the anomaly cancelation conditions when acting on the one-loop
induced Chern-Simons terms in the three- and five-dimensional effective theory.
The arising symmetries are argued to play a key role in the study of the
M-theory to F-theory limit on Calabi-Yau manifolds. For example, using the fact
that all fully resolved F-theory geometries inducing multiple Abelian gauge
groups or non-Abelian groups admit a certain set of symmetries, we are able to
generally show the cancelation of pure Abelian or pure non-Abelian anomalies in
these models.Comment: 48 pages, 2 figures; v2: typos corrected, comments on circle fluxes
adde
Different mechanism of two-proton emission from proton-rich nuclei Al and Mg
Two-proton relative momentum () and opening angle ()
distributions from the three-body decay of two excited proton-rich nuclei,
namely Al p + p + Na and Mg p
+ p + Ne, have been measured with the projectile fragment separator
(RIPS) at the RIKEN RI Beam Factory. An evident peak at MeV/c as
well as a peak in around 30 are seen in the two-proton
break-up channel from a highly-excited Mg. In contrast, such peaks are
absent for the Al case. It is concluded that the two-proton emission
mechanism of excited Mg is quite different from the Al case, with
the former having a favorable diproton emission component at a highly excited
state and the latter dominated by the sequential decay process
J/Psi and Psi' total cross sections and formation times from data for charmonium suppression in collisions
The recent data for E866 experiment on the x_F dependence for charmonium
suppression in pA collisions at 800 GeV are analyzed using a time- and
energy-dependent preformed charmonium absorption cross section
\sigma_{abs}^\psi(\tau,\sqrt{s}). For \sqrt{s}=10 GeV the initially (\tau=0)
produced premeson has an absorption cross section of \sigma_{pr}~3mb. At the
same energy but for \tau -> \infty one deduces for the total cross sections
\sigma_{tot}^{J/Psi N}=(2.8\pm 0.3)mb, \sigma_{tot}^{J/Psi N}= (10.5\pm 3.6)mb.
The date are compatible with a formation time \tau_{1/2}=0.6 fm/c.Comment: 13 pages of Latex including 2 figures; typos in the abstract are
correcte
Quantum states and linear response in dc and electromagnetic fields for charge current and spin polarization of electrons at Bi/Si interface with giant spin-orbit coupling
An expansion of the nearly free-electron model constructed by Frantzeskakis,
Pons and Grioni [Phys. Rev. B {\bf 82}, 085440 (2010)] describing quantum
states at Bi/Si(111) interface with giant spin-orbit coupling is developed and
applied for the band structure and spin polarization calculation, as well as
for the linear response analysis for charge current and induced spin caused by
dc field and by electromagnetic radiation. It is found that the large
spin-orbit coupling in this system may allow resolving the spin-dependent
properties even at room temperature and at realistic collision rate. The
geometry of the atomic lattice combined with spin-orbit coupling leads to an
anisotropic response both for current and spin components related to the
orientation of the external field. The in-plane dc electric field produces only
the in-plane components of spin in the sample while both the in-plane and
out-of-plane spin components can be excited by normally propagating
electromagnetic wave with different polarizations.Comment: 10 pages, 9 figure
On the order of an automorphism of a smooth hypersurface
In this paper we give an effective criterion as to when a positive integer q
is the order of an automorphism of a smooth hypersurface of dimension n and
degree d, for every d>2, n>1, (n,d)\neq (2,4), and \gcd(q,d)=\gcd(q,d-1)=1.
This allows us to give a complete criterion in the case where q=p is a prime
number. In particular, we show the following result: If X is a smooth
hypersurface of dimension n and degree d admitting an automorphism of prime
order p then p(d-1)^n then X is isomorphic to the Klein
hypersurface, n=2 or n+2 is prime, and p=\Phi_{n+2}(1-d) where \Phi_{n+2} is
the (n+2)-th cyclotomic polynomial. Finally, we provide some applications to
intermediate jacobians of Klein hypersurfaces
Monte Carlo simulations of an impurity band model for III-V diluted magnetic semiconductors
We report the results of a Monte Carlo study of a model of (III,Mn)V diluted
magnetic semiconductors which uses an impurity band description of carriers
coupled to localized Mn spins and is applicable for carrier densities below and
around the metal-insulator transition. In agreement with mean field studies, we
find a transition to a ferromagnetic phase at low temperatures. We compare our
results for the magnetic properties with the mean field approximation, as well
as with experiments, and find favorable qualitative agreement with the latter.
The local Mn magnetization below the Curie temperature is found to be spatially
inhomogeneous, and strongly correlated with the local carrier charge density at
the Mn sites. The model contains fermions and classical spins and hence we
introduce a perturbative Monte Carlo scheme to increase the speed of our
simulations.Comment: 17 pages, 24 figures, 2 table
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