Kaplan–Meier curves of progression-free survival (PFS) according to subgroups.

<p>A comparison of PFS and overall survival (OS) according to (A and B, respectively) pathological (n = 171) and (C and D, respectively) genetic classification (n = 158). Kaplan–Meier curves comparing PFS (E) and OS (F) associated with <i>IDH</i> mutant gliomas harboring CNAs +7q, +8q, −9p, and/or −11p with the PFS and OS of other <i>IDH</i> mutant gliomas (n = 73). Only patients who underwent an initial surgical intervention were included in these analyses. Abbreviations: mut; mutation, wt; wild-type.</p

CNAs frequently detected in <i>IDH</i> mutant gliomas.

<p>A comparison of CNAs found in <i>IDH</i> mutant gliomas (A) with wild-type <i>TP53</i> and (B) mutant <i>TP53</i>. The number of CNAs detected in both <i>IDH</i> mutant gliomas with wild-type and mutant <i>TP53</i> is summarized in a table.</p

Background of patients who underwent initial surgical intervention.

<p>A comparison of patient backgrounds according to histological classification (A) and genetic classification (B). In this table, oligoastrocytomas were classified as oligodendroglial tumor.</p><p>Background of patients who underwent initial surgical intervention.</p

A list of <i>IDH</i> mutant glioma patients with (A) and without (B) +7q, +8q, −9p, and/or −11p according to comparative genomic hybridization (CGH) analysis as well as their prognosis and <i>TP53</i> mutation status.

<p>The genetic type indicates detected the CNAs which are regarded as a favorable CNA (–1p/19q) or unfavorable CNAs (+7q, +8q, −9p, and/or −11p). A repeated number denoted by an asterisk indicates ta single patient who underwent multiple surgeries. Abbreviations: NA, not available.</p><p>A list of <i>IDH</i> mutant glioma patients with (A) and without (B) +7q, +8q, −9p, and/or −11p according to comparative genomic hybridization (CGH) analysis as well as their prognosis and <i>TP53</i> mutation status.</p