TUMOR MARKERS IN BONE MARROW IN PATIENTS WITH PROSTATIC CANCER

We compared prostatic specific acid phosphatase (PAP), prostatic specific antigen (PA) and γ-seminoprotein (γ-SM) levels between bone marrow and serum for the purpose of assessing of the usefulness of these tumor markers in early detection of bone metastasis in cases with prostatic cancer. Thirty-three patients were entered into this study. Of the patients, 20 had prostatic cancer including 11 with bone metastasis, and 13 patients had benign prostatic hypertrophy (BPH) served as controls. It seemed unlikely that bone marrow PAP, PA and γ-SM are more useful than their serum levels for detection of bone metastasis of prostatic cancer. Because correlation between bone marrow and serum levels of each marker was observed not only in cases with prostate cancer accompanied by bone metastasis but also in metastasis-free prostatic cancer and BPH cases, it seems likely that PAP, PA and γ-SM in bone marrow circulate from peripheral blood rather than from bone metastasis of prostatic cancer

景観・樹木に配慮した自然斜面の安定工法に関する基礎的研究

樹木を伐採せずに、かつ景観に配慮したロックボルト、ユニットネット併用による自然斜面の安定工法に関する基礎的な研究を行った。The stabilization technique of natural slope which maintained landscape and trees have been proposed. However, this method’s guidelines of design have not been established, because the mechanism of reinforcement is not clarified. In this paper, the laboratory and the in-situ test were carried out in order to obtain basic data of the “Unit Net” used by this method. As the results, it is clear that not fixing “Unit Net” at the intersection distributes the stress more widely than fixing “Unit Net”. Besides, it is recognized that the distribution of the stress is depended on the location and number of the rock bolt.「第11回岩の力学国内シンポジウム」　日時：平成14年1月24～25日　場所：(財)海外職業訓練協会（千葉県幕張

Gene Knock-Outs of Inositol 1,4,5-Trisphosphate Receptors Types 1 and 2 Result in Perturbation of Cardiogenesis

Rs in cardiogenesis remain unclear.Rs mimicked the phenotype of the AV valve defect that result from the inhibition of calcineurin, and it could be rescued by constitutively active calcineurin.Rs in cardiogenesis in part through the regulation of calcineurin-NFAT signaling