Carrier status of the 37 patients who underwent PGD.

<p>M: prior miscarriage, S: prior stillbirth, L: prior live birth, OR: the cycles of oocyte retrieval, ET: cycles of embryo transfer.</p><p>SA: spontaneous abortion, T: term delivery, IUFD: intrauterine fetal death, EP: ectopic pregnancy, BP: biochemical pregnancy.</p><p>Carrier status of the 37 patients who underwent PGD.</p

Subsequent live birth rate in patients who underwent PGD or conceived naturally.

<p>*Biochemical and ectopic pregnancies were included.</p><p>**A fetus with 21 trisomy was terminated at 18 weeks’ gestation.</p><p>***The cost is speculated to be lower. The cost ranged from $8,000–10,000 U.S. per trial in other hospitals in Japan. A technical charge was not included in the cost because this study was conducted for clinical research.</p><p>Subsequent live birth rate in patients who underwent PGD or conceived naturally.</p

Characteristics of the 89 patients with a history of recurrent pregnancy loss who underwent PGD or conceived naturally.

<p>Characteristics of the 89 patients with a history of recurrent pregnancy loss who underwent PGD or conceived naturally.</p

Carrier status of the 52 patients who conceived naturally.

<p>*Patients whose informed consent could not be obtained,</p><p>M: prior miscarriage, S: prior stillbirth, L: prior live birth, SA: spontaneous abortion, T: term delivery, IUFD: intrauteriine fetal death, EP: ectopic pregnancy, BP: biochemical pregnancy.</p><p>Carrier status of the 52 patients who conceived naturally.</p

Of 156 patients with reciprocal or Robertsonian translocations who received genetic counseling, 67 chose natural conception and 15 were excluded from the study.

<p>The remaining 89 chose PGD and 15 were excluded from the study. All comparisons were performed between the 37 patients of the PGD group who were ≤34 years old and the 52 patients who conceived naturally so that the patients who underwent PGD could be matched for age. The subsequent outcomes of the 126 patients were ascertained from the medical records and by telephone until July 2014.</p