154 research outputs found

    Magnetic conductivity and Chern-Simons Term in Holographic Hydrodynamics of Charged AdS Black Hole

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    We study the effects of the Chern-Simons term in the hydrodynamics of the five-dimensional Reissner-Nordstrom-AdS background. We work out the decoupling problem of the equations of motion and calculate the retarded Green functions explicitly. We then find that the Chern-Simons term induces the magnetic conductivity caused by the anomaly effect. It is increasing function of temperature running from a non-zero value at zero temperature to the twice the value at infinite temperature.Comment: 19 pages, 2 figures; v2 discussion on classification of perturbation fields based on helicity base, third order in dispersion relation and more discussion on magnetic conductivity are added, some typos are corrected and references are added; v3 published versio

    Comparison of Cerebral Blood Volume during Cold and Warm Stimulation in Elderly and Young Subjects

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    Background: Dementia involves a neuronal loss in the primary somatosensory cortex of the parietal lobe, causing dementia patients to perceive pain stimuli hardly. The function of temperature sensation declines. Studies measuring brain blood volume using near-infrared light have reported that patients suffering from dementia have less activation than healthy elderly people. However, the majority of these studies used tests related to cognitive function and the frontal lobe, and few have examined thermal sensation.Objective: The present study aimed to investigate the effect of cold and warm stimulation on cerebral blood volume in elderly and young subjects.Material and Methods: This observational study measured changes in oxygenated hemoglobin concentrations in the frontal cortex during cold and warm stimulation in elderly and young subjects using a near-infrared light device. The mean and standard deviation of the change in oxygenated hemoglobin concentration before and after cold and warm stimulation, as well as the center-of-gravity values, were compared between the young and the elderly.Results: During warm stimulation, the younger subjects showed an increase in blood oxygenated hemoglobin levels; however, the difference was not significant. For the elderly, no change was observed during the task. The center of gravity values was lower in the young compared to the elderly which was similar to the reaction threshold. No significant changes were observed during cold stimulation. Conclusion: Thermal sensation thresholds were impaired in the elderly compared to the young; however, cerebral blood volume changes were unclear

    THE DIGITAL WIDE BAND CHIRP PULSE GENERATOR AND PROCESSOR FOR PI-SAR2

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    BRIEF CONCLUSION This paper shows the digital wide band chirp pulse generator and processor for Pi-SAR2, and the history of its development at NEC. This generator and processor can generate the 150, 300 or 500MHz bandwidth chirp pulse and process the same bandwidth video signal. The offset video method is applied for this component in order to achieve small phase error, instead of I/Q video method for the conventional SAR system. Pi-SAR2 realized 0.3m resolution with the 500 MHz bandwidth by this component. After that, we had developed the experimental model of the digital wide band chirp pulse generator and processor for the airborne and spaceborne SAR in 2005. This model adopted the offset video method for the high performance, instead of the conventional I/Q video method. It had capabilities to generate the 300MHz bandwidth chirp pulse and to process video signals at 720MHz sampling rate for the input with 300MHz bandwidth. For the conventional signal generator by the I/Q video method, it is necessary to generate the In-phase(I) and Quadraturephase(Q) signals and to mix two signals using an analog I/Q modulator. The frequency of output signal from the wide band chirp generator is much higher than that of the conventional narrow one. Therefore mutual timing condition should be strictly required for the generation of two signals (I and Q) and its mixing. Otherwise the phase error of I/Q modulation would be large. On the other hand, it is not necessary to mix I/Q signals for the chirp pulse generation with the offset video method. Therefore there is no phase error of I/Q modulation in this method. This i

    An analysis of a constant current controlled Bi-directional DC-DC converter with digital control

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    This research aims at the development of switching power supply circuits that supply electric power from distributed power sources to electronic devices. A typical switching power supply uses constant voltage control, but in addition to constant voltage control, we propose constant current control enabled by means of digital PWM(pulse width modulation) control and a bidirectional DC-DC converter capable of converting energy in two directions using a single DC-DC converter [1-3]. This paper supposes that the aforementioned technology will be applied to streetlight systems that use solar cells, LEDs and batteries. Experiments on the charging operation using batteries and LEDs, as well as of the discharging operation using solar cells and batteries, were conducted, and this technology was evaluated based on those results.INTELEC 2009 - 2009 International Telecommunications Energy Conference : Incheon, South Korea, 2009.10.18-2009.10.2

    Clearance and Safety of the Radiocontrast Medium Iopamidol in Peritoneal Dialysis Patients

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    Although the characteristics and safety of radiocontrast media in peritoneal dialysis (PD) patients are not yet well defined, their use in PD patients is considered generally safe. In this study, we evaluated clearance and adverse events of iopamidol in PD patients. We measured the iopamidol concentration in the plasma, dialysate, and urine of 11 patients. Iopamidol clearance from patient plasma was delayed with a half-life of 33.3 h, and the elimination ratio was 83.6% for 96 h. We retrospectively investigated adverse events occurring in a total of 50 stable PD patients who underwent a total of 64 angiographic computed tomography (CT) scans. In 64 angiographic CT scans, two cases of adverse events were observed. Our results suggest that iopamidol can be eliminated by regular PD and careful observation for adverse events are necessary for the safe use of radiocontrast media

    Adamantinoma of the Tibia. - Report of a Case with Findings of Ultrastructural and Immunohistochemical Studies,

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    A case of tibial adamantinoma in a one-year and ten-month old girl is reported. She had gait disturbance and her roentogenogram showed a well circumscribed radiolucent area in the tibia. Light microscopic examination showed the epithelial component of nests and pseudoglandular arrays in the loose fibrous connective tissue. We finally diagnsed the tumor as adamantinoma of the tibia based on roentogenographical and histological findings. Moreover, the nature of the neoplastic cells was studied by the immunohistochemical and electron microscopic methods. The adamantinoma is regarded as a unique neoplasm capable of differen - tiating into epithelial elements as well as mesenchymal ones . Detection of epithelial component is important to differentiate from similar disorders. The fibrous dysplasia- like lesion in stroma is interpreted as a part of the spectrum of mesenchymal differentiation

    An Autopsy Case of Oligodendroglioma with Extracranial Metastases - A Statistical Review of Reported Cases -

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    An autopsy case of oligodendroglioma with extracranial metastases through blood vessels and cerebro-spinal fluid in a 44-year-old female is reported. Post-mortem examination revealed that the tumor involved the left frontal region, optic chiasma, cauda equina, spinal cord, subarachinoid space and bone (sternum, spine, ribs). Microscopic appearances showed the features of rapid anaplastic transformation. Glial fibrillary acidic protein (GFAP)-positive neoplastic oligodendrocytes were found in some areas of the honey-comb structure with prominant vascular stromata in recurrent and metastatic lesions. The histogenesis of this tumor may be interpreted as the constant or temporary production of GFAP by neoplastic oligodendrocytes as a sign of reversion to the fetal oligodendroglia without necessarily implying astrocytic hitogenesis. The present case is the second case of oligodendroglioma with extracranial metastases reported in Japan

    An Autopsy Case of Carcinosarcoma of the Esophagus

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    A case of carcinosarcoma, a rare polypoid tumor of the esophagus is presented. The characteristic gross and microscopic features as well as a discussion of the histogenesis of the sarcomatous elements are presented by microscopic, immunohistochemical and electron micronscopic examinations. Immunohistochemically, keratin and EMA (epithelial membrane antigen) were demonstrated in the islands of squamous cell carcinoma within the sarcomatous elements and in the carcinoma in situ at the border of normal mucosa. Vimentin, desmin, actin, myoglobin, factor VIII, S-100 protein, NSE, neuraminidase were not demonstrated in both the carcinomatous and the sarcomatous elements except for a positive reactivity to a-1-antichymotrypsin in the sarcomatous elements at part. It is suggested that the sarcomatous elements are of epithelial origin based on the facts as follows : 1 transition from overlying epithelium or carcinomatous islands to sarcomatous elements existent ; 2 some small tubules were formed within the sarcomatous elements, which showed transition into the sarcomatous elements ; and 3 a part of the sarcomatous elements revealed either positive or weak reactivity to keratin and EMA. Further, weak reactivity to keratin and EMA in the more anaplastic lesion may reflect the lack of tonofilaments and desmosomes in the ultrastructural findings

    Prospective Study of Gefitinib Readministration After Chemotherapy in Patients With Advanced Non-Small-Cell Lung Cancer Who Previously Responded to Gefitinib

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    The present study was designed to prospectively evaluate the clinical efficacy of gefitinib readministration in patients with advanced non-small cell lung cancer who responded well to initial gefitinib, followed by cytotoxic chemotherapy. Twenty subjects were enrolled, and 3 and 6 patients achieved partial response and stable disease, respectively. These findings provide valuable information for the management of previous gefitinib responders. Introduction: Salvage treatment for acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitor in patients with non-small-cell lung cancer is a matter of clinical concern. Several retrospective reports have indicated the usefulness of epidermal growth factor receptor tyrosine kinase inhibitor readministration; however, there have been few prospective studies. Materials and Methods: This study was designed to prospectively evaluate the clinical efficacy of gefitinib readministration in patients with advanced or metastatic non-small-cell lung cancer who responded well to initial gefitinib treatment. The subjects received at least 1 regimen of cytotoxic chemotherapy after progressive disease with the initial gefitinib therapy. Gefitinib administration (250 mg/d, orally) was started after progressive disease with the previous chemotherapeutic regimen. The primary endpoint in the present study was the response rate. Results: Twenty patients were enrolled between April 2007 and May 2011. Three patients achieved partial response, and 6 showed stable disease. Thus, the overall response rate and disease control rate of gefitinib readministration were 15% (95% Cl, 3.21-37.9) and 45% (95% Cl, 23.1-68.5), respectively. Median progression-free survival and overall survival from the start of gefitinib readministration were 2.0 months (95% Cl, 0.9-3.1 months) and 12.0 months (95% Cl, 8.0-16.0 months), respectively. Conclusion: These results suggest that gefitinib readministration may be an option, albeit with a low response rate and short progression-free survival, for patients who responded well to initial gefitinib followed by systemic chemotherapy. These findings provide valuable information for the management of previous gefitinib responders.ArticleCLINICAL LUNG CANCER. 13(6):458-463 (2012)journal articl
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